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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Research uncovers how complex protein pivotal in cancer development is activated

New research has uncovered how a complex protein pivotal in the development of cancer, viral infection and autoimmune diseases is activated.

10 Jul 2014

Exeter scientists find health benefits in rotten egg gas

It may smell of flatulence and have a reputation for being highly toxic, but when used in the right tiny dosage, hydrogen sulfide is now being being found to offer potential health benefits in a range of issues, from diabetes to stroke, heart attacks and dementia. A new compound (AP39), designed and made at the University of Exeter, could hold the key to future therapies, by targeting delivery of very small amounts of the substance to the right (or key) places inside cells.

10 Jul 2014

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize.

10 Jul 2014

New gene therapy may be effective for fighting fungal infections in cancer patients

Sleeping Beauty and fungal infections - not two items one would normally associate together, but for immunocompromised cancer patients they may prove to be a helpful combination.

9 Jul 2014

Samples from Chobani yogurt contain most virulent form of fungus

Samples isolated from Chobani yogurt that was voluntarily recalled in September 2013 have been found to contain the most virulent form of a fungus called Mucor circinelloides, which is associated with infections in immune-compromised people.

8 Jul 2014

High-resolution, high-throughput pre-implantation genetic screening microarray launched by OGT

Oxford Gene Technology (OGT), The Molecular Genetics Company, has announced the launch of a new high-resolution, high-throughput pre-implantation genetic screening (PGS) microarray aimed at improving embryo screening for in vitro fertilisation (IVF). The CytoSure™ Embryo Screen Array offers eight arrays of 60,000 spots for high-resolution genome-wide aneuploidy and copy number detection in pre-implantation embryos.

From Oxford Gene Technology 8 Jul 2014

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells.

8 Jul 2014

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Researchers from Case Western Reserve University School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either protect against, or contribute to Alzheimer's disease risk.

8 Jul 2014

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself - but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted.

8 Jul 2014

AutoGenomics, Genomas sign agreement to develop DNA-guided diagnostic systems

AutoGenomics, Inc, a leader in automated microarray technology for molecular diagnostics, and Genomas, a biomedical company enabling DNA-guided medicine for personal healthcare, announced today that they have signed an agreement to jointly develop genetic tests and DNA-guided diagnostic systems for optimal selection of statins and for improved delivery of statin therapy for the treatment of cardiovascular disease, obesity and diabetes.

7 Jul 2014

Research on intestinal microbiota overturns vision of human gut ecosystem

An international research team within the MetaHIT consortium coordinated by INRA and involving teams from CEA, CNRS and Université d'Evry, has developed a new method to analyse the global genome, or the metagenome of the intestinal microbiota.

7 Jul 2014

Scientists develop chip for detection of RNA strand of dengue fever virus

Scientists at the Center for Research and Advanced Studies (Cinvestav) in Mexico developed a chip (also known as cDNA microarray) that allows detection of the RNA strand of the dengue fever virus.

7 Jul 2014

Researchers map unknown microorganisms in human intestinal flora

Researchers from DTU Systems Biology have mapped 500 previously unknown microorganisms in human intestinal flora as well as 800 also unknown bacterial viruses (also called bacteriophages) which attack intestinal bacteria.

7 Jul 2014

Transcription factor IRF4 plays key role in brown fat's thermogenic process

The body contains two types of fat cells, easily distinguished by color: White and brown. While white fat serves to store excess calories until they're needed by the body, brown adipocytes actually burn fat by turning it into heat.

4 Jul 2014

Plasmonic biosensors: A key asset in personalised medicine

A new type of high-sensitivity and low-cost sensors, called plasmonic biosensors, could ultimately become a key asset in personalised medicine by helping to diagnose diseases at an early stage.

4 Jul 2014

Scientists find unexpected degree of complexity in transcriptional enhancers’ interactions

Contrary to what was thought, sequences of DNA called enhancers - which control a gene's output - find their targets long before they are activated during embryonic development, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

4 Jul 2014

Researchers discover new way by which metabolism is linked to regulation of DNA

A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer.

4 Jul 2014

Computer simulations show how two knots on DNA strand can interchange positions

Physicists of Johannes Gutenberg University Mainz and the Graduate School of Excellence "Materials Science in Mainz" (MAINZ) have been able with the aid of computer simulations to confirm and explain a mechanism by which two knots on a DNA strand can interchange their positions.

4 Jul 2014

genOway to provide EUCOMM conditional knockout mouse models to study human diseases

genOway, the biotechnology company dedicated to the development of genetically modified animal models, the Wellcome Trust Sanger Institute (UK) and Helmholtz Zentrum München (Germany), members of the EUCOMM Program (European Conditional Mouse Mutagenesis Program) and its successor program EUCOMMTOOLS (EUCOMM: Tools for functional annotation of the mouse genome) announce today the signing of a license enabling genOway to provide industry scientists with conditional knockout (KO) models developed by EUCOMM.

3 Jul 2014

Findings provide new insights into the basic biology of stem cells

A team of researchers from the University of California, San Diego School of Medicine, Oregon Health & Science University and Salk Institute for Biological Studies has shown for the first time that stem cells created using different methods produce differing cells.

3 Jul 2014

DNA News and Research

Further Reading

Research uncovers how complex protein pivotal in cancer development is activated

Exeter scientists find health benefits in rotten egg gas

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

New gene therapy may be effective for fighting fungal infections in cancer patients

Samples from Chobani yogurt contain most virulent form of fungus

High-resolution, high-throughput pre-implantation genetic screening microarray launched by OGT

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

AutoGenomics, Genomas sign agreement to develop DNA-guided diagnostic systems

Research on intestinal microbiota overturns vision of human gut ecosystem

Scientists develop chip for detection of RNA strand of dengue fever virus

Researchers map unknown microorganisms in human intestinal flora

Transcription factor IRF4 plays key role in brown fat's thermogenic process

Plasmonic biosensors: A key asset in personalised medicine

Scientists find unexpected degree of complexity in transcriptional enhancers’ interactions

Researchers discover new way by which metabolism is linked to regulation of DNA

Computer simulations show how two knots on DNA strand can interchange positions

genOway to provide EUCOMM conditional knockout mouse models to study human diseases

Findings provide new insights into the basic biology of stem cells

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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