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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.

31 May 2014

Genetic changes can predict which patient will benefit from chemotherapy before bladder cancer surgery

Three genetic changes can predict whether a patient will benefit from chemotherapy before surgery to remove bladder cancer, according to new findings presented by Fox Chase Cancer Center researchers during the 50th Annual Meeting of the American Society of Clinical Oncology.

31 May 2014

DNA-binding fluorescent dyes evaluate cytotoxicity in real-time during screening

High throughput screening of compounds in live cells is a powerful approach for discovering new drugs, but the potential for cell toxicity must be considered.

31 May 2014

Inovio Pharmaceuticals’ reverse stock split to become effective on June 5, 2014

Inovio Pharmaceuticals, Inc. today announced that its previously announced 1-for-4 reverse stock split shall become effective at 5 P.M., Thursday, June 5, 2014, and trading of the Company's common stock on a post-reverse split basis shall commence on Friday, June 6, 2014.

30 May 2014

EKF, GILUPI report data on circulating tumour cell DNA enrichment, mutation detection

EKF and GILUPI, announce results from collaborative work using GILUPI CellCollector and EKF Molecular’s PointMan DNA Enrichment technology.

From EKF Diagnostics 30 May 2014

Gene regulation responsible for normal breast tissue may also play role in cancer development

About one in eight women in the United States will contract breast cancer in her lifetime. Now new research from Tel Aviv University-affiliated researchers, in collaboration with Johns Hopkins University, has provided another tool to help women, clinicians, and scientists searching for a cure to the one of the most widespread yet incurable diseases on the planet.

30 May 2014

Researchers uncover previously unidentified genes responsible for keloid scarring

Researchers at Henry Ford Hospital in Detroit have uncovered previously unidentified genes that may be responsible for keloid scarring, a discovery that could unlock the mystery of keloid development and provide insight for more effective treatment.

30 May 2014

Findings have important implications for improving war wound healing

War wounds that heal successfully frequently contain different microbial species from those that heal poorly, according to a paper published ahead of print in the Journal of Clinical Microbiology.

30 May 2014

New insights into egg selection may have broad implications for women's health, fertility

A woman's supply of eggs is a precious commodity because only a few hundred mature eggs can be produced throughout her lifetime and each must be as free as possible from genetic damage.

30 May 2014

New research shows how misfolded proteins are precisely selected for degradation

It's almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood.

30 May 2014

Female mice deprived of dietary zinc before conception experience fertility problems

Female mice deprived of dietary zinc for a relatively short time before conception experienced fertility and pregnancy problems and had smaller, less-developed fetuses than mice that ingested zinc during the same times, according to researchers in Penn State's College of Agricultural Sciences.

30 May 2014

Study reveals how BTK mutation triggers drug resistance in CLL patients

A multi-institutional team of researchers has pinpointed exactly what goes wrong when chronic lymphocytic leukemia (CLL) patients develop resistance to ibrutinib, a highly effective, precisely targeted anti-cancer drug.

29 May 2014

Researchers create initial catalog of human proteome, identify 193 novel proteins

Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human "proteome," or all of the proteins in the human body.

29 May 2014

State highlights: Mental health funding in Kansas; EHR problems claim CEO's job; 'litany of woes' at IHS

A selection of health policy stories from Arkansas, Florida, Georgia, Kansas, Michigan, Montana, Ohio, and Wyoming.

29 May 2014

UT Southwestern researchers identify protein critical to the spread of deadly cancer cells

UT Southwestern Medical Center cancer researchers have identified a protein critical to the spread of deadly cancer cells and determined how it works, paving the way for potential use in diagnosis and eventually possible therapeutic drugs to halt or slow the spread of cancer.

29 May 2014

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

A multicenter team of researchers report that a commercial test designed to rule out the presence of genetic biomarkers of prostate cancer may be accurate enough to exclude the need for repeat prostate biopsies in many — if not most — men.

29 May 2014

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

29 May 2014

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

The overall number and nature of mutations—rather than the presence of any single mutation—influences an individual's risk of developing schizophrenia, as well as its severity, according to a discovery by Columbia University Medical Center researchers published in the latest issue of Neuron.

29 May 2014

Researchers find link between aging and chemicals in environment

Why are some 75-year-olds downright spry while others can barely get around? Part of the explanation, say researchers writing in the Cell Press journal Trends in Molecular Medicine on May 28, is differences from one person to the next in exposure to harmful substances in the environment, chemicals such as benzene, cigarette smoke, and even stress.

29 May 2014

Polyplus-transfection introduces FectoPRO transfection reagent

Polyplus-transfection SA, a privately-held company specializing in the development of innovative solutions for transfection, today announces the launch of FectoPRO, the latest optimised transfection reagent in their product portfolio. FectoPRO has been designed for high yields in medium and large-scale production of proteins and antibodies in mammalian cells.

28 May 2014

DNA News and Research

Further Reading

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

Genetic changes can predict which patient will benefit from chemotherapy before bladder cancer surgery

DNA-binding fluorescent dyes evaluate cytotoxicity in real-time during screening

Inovio Pharmaceuticals’ reverse stock split to become effective on June 5, 2014

EKF, GILUPI report data on circulating tumour cell DNA enrichment, mutation detection

Gene regulation responsible for normal breast tissue may also play role in cancer development

Researchers uncover previously unidentified genes responsible for keloid scarring

Findings have important implications for improving war wound healing

New insights into egg selection may have broad implications for women's health, fertility

New research shows how misfolded proteins are precisely selected for degradation

Female mice deprived of dietary zinc before conception experience fertility problems

Study reveals how BTK mutation triggers drug resistance in CLL patients

Researchers create initial catalog of human proteome, identify 193 novel proteins

State highlights: Mental health funding in Kansas; EHR problems claim CEO's job; 'litany of woes' at IHS

UT Southwestern researchers identify protein critical to the spread of deadly cancer cells

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

Researchers find link between aging and chemicals in environment

Polyplus-transfection introduces FectoPRO transfection reagent

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