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Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

A synthetic viral vector and a novel surgical approach developed at Mass Eye and Ear has enabled efficient gene transfer into the inner ear of nonhuman primates, a research team working towards the development of effective treatments for hearing loss and vestibular disorders has reported.

15 Mar 2022

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Stand Up To Cancer and Zentalis Pharmaceuticals, Inc. today announced that Zentalis will contribute $1 million to the SU2C Catalyst program to support research that investigates the use of certain small molecule inhibitors for treating a variety of cancer types.

15 Mar 2022

Disability-free life expectancy improving even for people with common chronic conditions

The number of healthy years a person lives is, on average, increasing even for people with common chronic conditions, according to a new study publishing March 15th in PLOS Medicine by Holly Bennett of Newcastle University, UK, and colleagues.

15 Mar 2022

Spray-on technology using customized gold nanoparticles could help treat heart disease

Could a spritz of super-tiny particles of gold and peptides on a damaged heart potentially provide minimally invasive, on-the-spot repair?

15 Mar 2022

Orally-active senolytics can boost a key beneficial protein in mice and humans

Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases.

15 Mar 2022

Study takes a new approach to looking at de novo genetic variants in autism

About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA contributes to the development of ASD has been more of a mystery.

15 Mar 2022

Recovery of consciousness may take weeks for most COVID patients on respirators

Most patients with severe COVID who are put on ventilators regain consciousness after removal of respiratory support, but recovery may take weeks after the period of mechanical ventilation has ended, according to a new study by investigators at Weill Cornell Medicine, Columbia University Vagelos College of Physicians and Surgeons, Harvard Medical School, NewYork-Presbyterian and Massachusetts General Hospital.

15 Mar 2022

New way to deliver potential HIV vaccine using mRNA technology

Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.

15 Mar 2022

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study led by Johns Hopkins Kimmel Cancer Center researchers suggests.

15 Mar 2022

Routine mammograms may provide clues for heart disease risk in postmenopausal women

Routine mammograms may provide key insights for cardiovascular disease. Detection of breast arterial calcifications on breast mammograms was associated with a higher risk of cardiovascular disease in postmenopausal women, according to new research published today in Circulation: Cardiovascular Imaging, a peer-reviewed journal of the American Heart Association journal.

15 Mar 2022

Mason scientists receive DOD funding for breast cancer prevention and treatment research

George Mason University College of Science announced a $1.57 million dollar grant from the Department of Defense to fund a transformative approach for breast cancer treatment developed by scientists in Mason's Center for Drug Discovery for Rare Diseases.

15 Mar 2022

Researchers identify a potential new test for early diagnosis of Lyme disease

For scientists and clinicians alike, one of the Holy Grails for successfully treating and curing Lyme disease is developing tests that identify the disease sooner, show when people are cured of infection, and can diagnose reinfection.

15 Mar 2022

Study shows genetic link between endometriosis and ovarian cancer subtypes

University of Queensland researchers have demonstrated a genetic link between endometriosis and ovarian cancer subtypes enabling them to identify potential drug targets for therapy and increasing the understanding of both diseases.

15 Mar 2022

High doses of antibiotic may safely and effectively treat TB meningitis

A Johns Hopkins Children's Center-led study in animals suggests that high doses of a widely used antibiotic called rifampin may safely treat and reduce the duration of treatment for the deadliest form of tuberculosis that affects the brain, potentially improving survival rates for patients and decreasing the likelihood of lasting adverse effects of the disease.

15 Mar 2022

Small airways disease is a potential long-lasting effect of COVID-19, study says

Disease of the small airways in the lungs is a potential long-lasting effect of COVID-19, according to a new study published in the journal Radiology.

15 Mar 2022

Cognitive decline found to be the key factor in predicting life expectancy for Alzheimer's patients

Cognitive decline is the biggest factor in determining how long patients with Alzheimer's disease will live after being diagnosed, according to a new study from researchers at UT Southwestern.

15 Mar 2022

‘An Arm and a Leg’: Need an expensive drug? Here’s what you need to know

Lillian Karabaic teaches personal finance to millennials through a podcast and community called Oh My Dollar! — and she needs an expensive drug to treat a chronic condition.

15 Mar 2022

Study results in three new co-amorphous drug systems with great anti-COVID-19 potential

Researchers demonstrated that the bioavailability of matrine-type alkaloids could be prolonged by employing a co-former, resveratrol.

15 Mar 2022

Rat study shows how several brain regions work together to acquire a skill and replicate it

Learning a complex skilled movement like tying your shoes or playing an instrument takes practice. After repeating the same movements over and over, people often develop a formulaic way of performing the task, and may not even have to think about it anymore.

14 Mar 2022

Research finds many undetected cancer cases due to the COVID-19 pandemic

Research in the March 2022 issue of JNCCN-;Journal of the National Comprehensive Cancer Network examined data from the Ontario Cancer Registry from September 25, 2016 through September 26, 2020, to determine the impact of the COVID-19 pandemic on the number of new cancer cases detected.

14 Mar 2022

Medicine News and Research

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Disability-free life expectancy improving even for people with common chronic conditions

Spray-on technology using customized gold nanoparticles could help treat heart disease

Orally-active senolytics can boost a key beneficial protein in mice and humans

Study takes a new approach to looking at de novo genetic variants in autism

Recovery of consciousness may take weeks for most COVID patients on respirators

New way to deliver potential HIV vaccine using mRNA technology

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Routine mammograms may provide clues for heart disease risk in postmenopausal women

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Researchers identify a potential new test for early diagnosis of Lyme disease

Study shows genetic link between endometriosis and ovarian cancer subtypes

High doses of antibiotic may safely and effectively treat TB meningitis

Small airways disease is a potential long-lasting effect of COVID-19, study says

Cognitive decline found to be the key factor in predicting life expectancy for Alzheimer's patients

‘An Arm and a Leg’: Need an expensive drug? Here’s what you need to know

Study results in three new co-amorphous drug systems with great anti-COVID-19 potential

Rat study shows how several brain regions work together to acquire a skill and replicate it

Research finds many undetected cancer cases due to the COVID-19 pandemic

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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