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New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

Study sheds light on biological mechanisms that drive rare pediatric neurogenetic disorders

Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino acid supplement might offer a targeted therapy.

22 Feb 2018

Epigenetic changes due to normal aging process linked to cancer risk

Some scientists have hypothesized that tumor-promoting changes in cells during cancer development--particularly an epigenetic change involving DNA methylation--arise from rogue cells escaping a natural cell deterioration process called senescence.

22 Feb 2018

Beetroot may reduce kidney failure risk after heart x-ray, research reveals

Beetroot may reduce the risk of kidney failure in patients having a heart x-ray, according to research led by Queen Mary University of London.

22 Feb 2018

Study sheds light on how glial cells control the function of nerve cells

Research has uncovered how glial cells could modulate the activity of nerve cells. The study suggests that glial cells modulate neurotransmitter release by increasing the acidity of the immediate extracellular environment.

22 Feb 2018

3D Signatures reports positive results of new Telo-HL test for Hodgkin's lymphoma

3D Signatures Inc. is pleased to announce that a preliminary third-party analysis of the trial data for Telo-HL, 3DS' test in development for Hodgkin's lymphoma (HL), shows that the Company's TeloViewTM platform is able to distinguish, with a high degree of statistical significance, multiple differences between a patient group that responds to standard ABVD chemotherapy, and a group that relapses or is refractory to treatment within the first 12 months.

22 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Scientists reveal development of improved medicine to fight addiction

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue.

21 Feb 2018

Liquefied brain tissue after stroke may harm surviving brain, UA study finds

Scientists have known for years that the brain liquefies after a stroke. If cut off from blood and oxygen for a long enough period, a portion of the brain will die, slowly morphing from a hard, rubbery substance into liquid goop.

21 Feb 2018

Pioneering study may pave way for effective painkillers to treat neuropathic pain

A pioneering international study, carried out by the University of Granada, Harvard University, the University of California, Los Angeles, the University of Florida, Laval University and the Jackson Laboratory has conducted an in-depth analysis of the molecular differences between the most common symptoms associated with neuropathic pain.

21 Feb 2018

Research project aims to find new ways to identify and treat most aggressive brain cancers

A large European research collaboration is bringing new technology to bear to combat two of the most aggressive brain cancers.

21 Feb 2018

KNAUER joins UN Global Compact initiative for responsible corporate governance

The UN Global Compact is the world's largest and most important initiative for responsible corporate governance, involving more than 12,800 companies and organizations from more than 160 countries, 454 of them from Germany.

From KNAUER Wissenschaftliche Geräte GmbH 21 Feb 2018

Study reveals biological relevance of sex in effects of D-galactose induced aging

A research study by the Universitat Autònoma de Barcelona in collaboration with the University of La Laguna demonstrates in mice the biological relevance of sex in the effects of accelerated ageing caused by a chronic treatment of D-galactose, a sugar found abundantly in milk and to a lesser extent in fruits and vegetables.

20 Feb 2018

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development.

20 Feb 2018

Computerized tissue-imaging may help predict early recurrence of lung cancer

Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease.

20 Feb 2018

Gout medication may help improve heart function in adult patients

Researchers at the University of Cincinnati College of Medicine have shown that probenecid, a drug long used to treat gout, may be able to improve heart function in adult patients who experience heart failure.

20 Feb 2018

Immune history influences person's response to flu vaccine

New research on why the influenza vaccine was only modestly effective in recent years shows that immune history with the flu influences a person's response to the vaccine.

20 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018

Liquid biopsies could be used as new predictive marker for metastatic TNBC

A clinically relevant "liquid biopsy" test can be used to profile cancer genomes from blood and predict survival outcomes for patients with metastatic triple negative breast cancer, according to new research published by a multi-institutional team of researchers with The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

19 Feb 2018

Study sheds light on biology that guides behavior across different stages of life

Put 50 newborn worms in 50 separate containers, and they'll all start looking for food at roughly the same time. Like members of other species, microscopic C. elegans roundworms tend to act like other individuals their own age.

19 Feb 2018