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Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Researchers uncover novel strategy to program immune system for fighting cancer

Looking to bolster the body's immune system in the fight against infection and cancer, researchers at the University of California San Diego and their colleagues have identified a promising new strategy to program the immune system to meet the pathogen or malignancy in the tissues where they first pose a threat.

11 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

Scientists discover specific mechanism of Zika virus-associated microcephaly

Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex.

11 Dec 2017

Study: Employees with influenza have more lost work time

Employees with laboratory-confirmed influenza have more lost work time- including absences and reduced productivity while at work- compared to those with other types of acute respiratory illness (ARI), reports a study in the December Journal of Occupational and Environmental Medicine.

11 Dec 2017

TPU researchers create 3D-printed models of children's hearts

Scientists from Tomsk Polytechnic University are creating 3D-printed models of children's hearts. They are printed based on magnetic resonance imaging of real patients. These models are used as simulators for cardiac surgeons to plan and pre-work forthcoming operations.

11 Dec 2017

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

Canola oil linked to worsening of Alzheimer’s

Canola oil has been marketed as a healthy cooking oil choice because of the low levels of saturated fats that is seen in it. Now a new study has revealed that consumption of canola oil could be linked to worsening of memory functions and learning ability in patients with Alzheimer’s disease.

11 Dec 2017

Salk scientists unravel mystery about how the spinal cord deals with different information

We think of our brain as masterminding all of our actions, but a surprising amount of information related to movement gets processed by our spinal cord.

8 Dec 2017

Scientists discover how axons in developing visual system stabilize their connections

Scientists at Tokyo Tech have made an important discovery concerning the development of layer-specific axonal connections in the developing visual system of Drosophila flies.

8 Dec 2017

University of Adelaide receives $23.2 million for preterm birth research

The University of Adelaide has been awarded $23.2 million for new research tackling some of the world's most significant health problems, including one of the biggest killers of children: preterm birth.

8 Dec 2017

Parental lifespan genes could pave way for new therapeutic targets to prolong life

A large-scale international study led by the University of Exeter Medical School has discovered new genes linked to parents' lifespan - which could one day be targeted to help prolong human life.

8 Dec 2017

Large-scale study expands number of genetic markers linked to exceptional longevity

A new large-scale international study expands the number of genetic markers now known to be associated with exceptional longevity.

7 Dec 2017

Malaria parasite employs active strategy to deceive the immune system

Global efforts to eradicate malaria are crucially dependent on scientists' ability to outsmart the malaria parasite. And Plasmodium falciparum is notoriously clever: It is quick to develop resistance against medications and has such a complex life cycle that blocking it effectively with a vaccine has thus far proved elusive.

7 Dec 2017

Study links canola oil consumption with worsened memory, learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health.

7 Dec 2017

Research findings offer path for drug discovery to treat hyperaldosteronism

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute, in collaboration with researchers at Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health, identifies a mechanism that explains the development of hyperaldosteronism.

7 Dec 2017

New tests offer better chance for more accurate detection of Lyme disease

New tests to detect early Lyme disease - which is increasing beyond the summer months -could replace existing tests that often do not clearly identify the infection before health problems occur.

7 Dec 2017

UA researcher awarded $2.3 million NIH grant to develop new treatments for depression

A University of Arizona College of Medicine-Phoenix researcher has received a $2.3 million grant from the National Institutes of Health to develop new treatments for depression.

7 Dec 2017