Lungs News and Research

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Research findings on pediatric ILD published online in PED

An insightful and in-depth presentation of the most up-to-date clinical and research findings and historical perspectives on pediatric interstitial lung disease is presented in a special issue published online ahead of print in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc.

26 May 2010

Visually-guided laser-balloon catheter stops abnormal electrical pulses in patients with irregular heartbeats

A new treatment known as a visually-guided laser-balloon catheter successfully interrupted abnormal electrical pulses in patients and pigs with intermittent, irregular heartbeats, in a study reported in Circulation: Arrhythmia and Electrophysiology, a journal of the American Heart Association.

26 May 2010

Anaheim Regional Medical Center uses Arctic Sun cooling device to protect a patient from brain damage

A day after delivering her fourth child at Anaheim Regional Medical Center in Anaheim, California last December, 34-year-old Brynn Ervin suffered a cardiac arrest, the result of massive blood clots lodged in the main arteries that take blood to her lungs. Desperate to save the life of the young mother, the cardiac arrest team performed 95 minutes of CPR.

25 May 2010

Clovis Oncology, Avila Therapeutics announce development agreement for NSCLC EMSI program

Clovis Oncology, Inc., a biopharmaceutical company focused on acquiring, developing and commercializing innovative anti-cancer agents, and Avila Therapeutics, Inc., a biotechnology company designing targeted covalent drugs, announced today an agreement for the development and commercialization of Avila's epidermal growth factor receptor (EGFR) mutant-selective inhibitor (EMSI) program, currently in pre-clinical development for the treatment of non-small cell lung cancer (NSCLC).

25 May 2010

USPTO issues composition of matter patent for Transave's ARIKACE

Transave Inc. today announced that the United States Patent and Trademark Office has issued an important composition of matter patent (U.S. Patent No. 7,718,189) for liposomal aminoglycoside formulations including its lead compound, ARIKACE™ (liposomal amikacin for inhalation). The company expects that the patent will provide exclusivity for ARIKACE until October 1, 2026.

25 May 2010

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

Researchers at Mount Sinai School of Medicine for the first time have determined that bone marrow cells play a critical role in fighting respiratory viruses, making the bone marrow a potential therapeutic target, especially in people with compromised immune systems. They have found that during infections of the respiratory tract, cells produced by the bone marrow are instructed by proteins to migrate to the lungs to help fight infection. The data are published in the current issue of Cell Host & Microbe.

25 May 2010

New research finding may change direction of vaccine research for M. tuberculosis

Scientists at NYU Langone Medical Center have discovered that the strategy of "immune evasion" common to many viruses, bacteria and parasites, is uncommon to M. tuberculosis where the antigens remain strikingly unchanged and homogenous. The study published in Nature Genetics on May 23, 2010, suggests that M. tuberculosis antigens do not mutate because they hope to be recognized by the body's immune system- perhaps because the host immune mechanism that leads to the typical lung destruction and cough can contribute to the spread of the disease.

25 May 2010

Positive results from Phase 2 clinical trial for STA-9090 in Stage IIIB and Stage IV patients with NSCLC

Synta Pharmaceuticals Corp. today announced that clinical activity seen in the first stage of its trial for STA-9090 in Stage IIIB and Stage IV patients with non-small cell lung cancer, support advancing to the second stage of the trial. This result was achieved in the first pre-defined patient cohort to complete enrollment.

25 May 2010

Reducing consumption of sugary drinks can lower blood pressure: Research

Research led by Liwei Chen, MD, PhD, Assistant Professor of Public Health at LSU Health Sciences Center New Orleans, has found that there is an association between sugary drinks and blood pressure and that by cutting daily consumption of sugary drinks by just one serving a day, people can lower their blood pressure.

25 May 2010

Beta-blocker medications provide new hope for patients with COPD: Study

Patients with chronic obstructive pulmonary disease may have fewer respiratory flare-ups and longer survival if they take beta-blocker medications, according to a report in the May 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

25 May 2010

Underestimated cancer risks related to radon exposure

A report recently released by the President's Cancer Panel focuses on underestimated cancer risks related to environmental contaminants and other harmful exposures, including radon.

24 May 2010

Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Bristol-Myers Squibb Company today announced positive results from a randomized Phase 2 study evaluating ipilimumab in combination with standard chemotherapy in previously untreated patients with advanced non-small cell lung cancer.

21 May 2010

Updates on Micromet's BiTE antibody development programs to be made at two medical conferences

Micromet, Inc., a biopharmaceutical company focused on the development and commercialization of next-generation antibodies for the treatment of cancer, today announced that updates on several of its BiTE antibody development programs will be made at two upcoming medical conferences.

21 May 2010

ArQule announces presentations on ARQ 197 c-Met inhibitor at 2010 ASCO

ArQule, Inc. today announced that the following presentations of clinical data for ARQ 197, a selective inhibitor of the c-Met receptor tyrosine kinase, will take place at the 2010 American Society of Clinical Oncology (ASCO) Annual Meeting, which will be held June 4-8, 2010 in Chicago, Illinois.

21 May 2010

Washington State Department of Health shows smoking inside homes drops by 61% since 2000

New research released today by the Washington State Department of Health shows the number of people smoking inside homes in our state has declined by 61 percent since 2000. The drop is more than double the overall decline in adult smoking during the same period.

21 May 2010

Combination of reovirus and carboplatin/paclitaxel shows promising anticancer activity in SCCHN

Oncolytics Biotech Inc. announced today that abstracts covering clinical research with reovirus (REOLYSIN(R)) are available on the American Society of Clinical Oncology website at www.asco.org, and on the Oncolytics website at www.oncolyticsbiotech.com.

21 May 2010

Cancer Institute of New Jersey investigators target autophagy

In an effort to improve current anticancer treatments, investigators at The Cancer Institute of New Jersey (CINJ) have been targeting a process known as autophagy, in which cancer cells eat themselves as a measure of self preservation under chemotherapy and radiation stress, thus prolonging tumor cell survival and inducing resistance to therapy.

21 May 2010

New data highlighting Pfizer's approach to cancer drug development to be presented at ASCO meeting

Pfizer Oncology will present new data highlighting the company's focused approach to cancer drug development through the identification and validation of molecular targets. These results will be presented at the 46th Annual American Society of Clinical Oncology meeting in Chicago from June 4-8.

21 May 2010

Data from three Phase II clinical trials of PS-targeting antibody to be presented at 2010 ASCO Annual Meeting

Peregrine Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing innovative monoclonal antibodies for the treatment of cancer and viral infections, will present data from three Phase II clinical trials highlighting the clinical potential of its unique phosphatidylserine -targeting antibody bavituximab for the treatment of solid tumors.

21 May 2010

Vitamin D plays much wider role in people's life

Vitamin D is the sunshine vitamin - we make it when our skin is exposed to UV rays. In a perfect world everyone would eat fresh, organic foods, get outside, and enjoy a little sunshine all year round. But with today's busy lifestyles and concerns about skin cancer many people are vitamin D deficient and don't know it.

21 May 2010

Lungs News and Research

Research findings on pediatric ILD published online in PED

Visually-guided laser-balloon catheter stops abnormal electrical pulses in patients with irregular heartbeats

Anaheim Regional Medical Center uses Arctic Sun cooling device to protect a patient from brain damage

Clovis Oncology, Avila Therapeutics announce development agreement for NSCLC EMSI program

USPTO issues composition of matter patent for Transave's ARIKACE

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

New research finding may change direction of vaccine research for M. tuberculosis

Positive results from Phase 2 clinical trial for STA-9090 in Stage IIIB and Stage IV patients with NSCLC

Reducing consumption of sugary drinks can lower blood pressure: Research

Beta-blocker medications provide new hope for patients with COPD: Study

Underestimated cancer risks related to radon exposure

Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Updates on Micromet's BiTE antibody development programs to be made at two medical conferences

ArQule announces presentations on ARQ 197 c-Met inhibitor at 2010 ASCO

Washington State Department of Health shows smoking inside homes drops by 61% since 2000

Combination of reovirus and carboplatin/paclitaxel shows promising anticancer activity in SCCHN

Cancer Institute of New Jersey investigators target autophagy

New data highlighting Pfizer's approach to cancer drug development to be presented at ASCO meeting

Data from three Phase II clinical trials of PS-targeting antibody to be presented at 2010 ASCO Annual Meeting

Vitamin D plays much wider role in people's life

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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