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Pearl Therapeutics presents data supporting development of PT003 combination bronchodilator product

Pearl Therapeutics Inc., a company developing clinically differentiated double and triple combination therapies for the treatment of highly prevalent chronic respiratory diseases, presented results from four studies that provide support for further development of PT003, the company's fixed dose combination of glycopyrrolate and formoterol delivered via a pressurized hydrofluoroalkane metered dose inhaler (HFA-MDI).

19 May 2010

Low blood phosphorus levels associated with high death rates in African AIDS patients: Research

Low blood phosphorus levels are associated with high death rates in the initial weeks of antiretroviral therapy (ART) in AIDS patients in sub-Saharan Africa, according to new research conducted by University of Alabama at Birmingham researchers at the UAB-affiliated Centre for Infectious Disease Research in Zambia.

19 May 2010

CIHR experts discuss rising consumption of cigarettes among women

Often marketed as symbols of independence, freedom and pleasure for women, cigarettes are highly addictive, expensive and detrimental to the health of smokers and those who share their environment. By 2025, the World Health Organization predicts that 20% of women will smoke, compared to 12% today. In Canada, over 17,000 women die from smoking related causes each year.

19 May 2010

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

Cancer Research UK scientists have discovered sophisticated 'watchman' cells in humans that can instruct the immune system to destroy foreign invaders like viruses and cancer cells, according to research published in The Journal of Experimental Medicine.

19 May 2010

NAC therapy shows promise for patients with mild IPF

A new therapy shows promise for patients with mild idiopathic pulmonary fibrosis. According to researchers in Japan, inhaled N-acetylcysteine monotherapy preserves more lung function in some idiopathic pulmonary fibrosis patients than no therapy.

19 May 2010

Oncolytics announces publication of Phase Ia/Ib U.K. clinical trial results of REOLYSIN for cancer

Oncolytics Biotech Inc. announced today that a paper entitled "Two-Stage Phase I Dose-Escalation Study of Intratumoural Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers," has been published in the online version of the journal Clinical Cancer Research.

19 May 2010

Immunetics receives $2.8M contract as part of NHLBI's REDS-II project

Immunetics, Inc. has been selected to receive a $2.8 million contract as part of the National Heart, Lung, and Blood Institute's Retrovirus Epidemiology Donor Study-II project, a long term epidemiologic study of blood safety involving HIV and other infectious and non-infectious complications of blood transfusion.

18 May 2010

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

Human stem cells administered intravenously can restore alveolar epithelial tissue to a normal function in a novel ex vivo perfused human lung after E. coli endotoxin-induced acute lung injury, according to research from the University of California San Francisco.

18 May 2010

High school student studies effects of repeated x-rays in HMV children admitted for pneumonia

You expect to find leading experts in the fields of pulmonary, critical care and sleep medicine presenting their research at the annual ATS International Conference-physicians and professors, basic scientists, fellows and post-docs, certainly. High school students? Not so much.

18 May 2010

Study confirms genetic overlap for susceptibility to COPD and lung cancer

New research shows genes that make smokers more likely to develop chronic obstructive pulmonary disease (COPD), or emphysema, are also closely linked to an increased likelihood of developing lung cancer, according to studies presented today at the American Thoracic Society's annual meeting.

18 May 2010

Cancer Research UK launches new cancer centre in Leeds

LEEDS today joins a unique chain of Cancer Research UK Centres that are being launched across the UK.

18 May 2010

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

The data from the initial clinical studies with KB001, a novel antibody fragment against PcrV on Pseudomonas aeruginosa (Pa) bioengineered by KaloBios Pharmaceuticals, Inc. and partnered with sanofi pasteur, demonstrated promising therapeutic activity in the prevention of serious lung infection in mechanically ventilated patients colonized with the bacterium and in limiting potentially damaging inflammation in patients with cystic fibrosis, where Pa plays an important role in the disease.

18 May 2010

UMPIRE trial of Red Heart Pill launched to combat cardiovascular problems

Researchers will be exploring whether a new, very low cost, one-a-day combined 'polypill' could reduce the risk of heart attacks, strokes and other cardiovascular problems across the world, in a major new international trial that launches today.

18 May 2010

Apnex HGNS System shows promising results in people suffering from OSA

Apnex Medical announced today that preliminary data from a first-in-man clinical study showed significant improvements in sleep for people suffering from obstructive sleep apnea. The Apnex HGNS™ System, developed by the St. Paul-based company, is a device designed to treat OSA, which is a serious life-threatening illness characterized by fragmented sleep and excessive day-time sleepiness.

18 May 2010

FibroGen's FG-3019 human monoclonal antibody against CTGF reverses progression of lung fibrosis

FibroGen, Inc. today announced that administration of investigational therapy FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), reversed the process of fibrosis in a preclinical model of radiation-induced lung fibrosis, a finding that has implications for treating multiple types of fibrotic disease.

18 May 2010

WaferGen Biosystems first-quarter revenues increase to $389,785

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genome analysis systems, today reported performance results for the first quarter ended March 31, 2010.

17 May 2010

Mpex Pharmaceuticals presents Phase 2b trial results of Aeroquin for cystic fibrosis at ATS Annual Meeting

Mpex Pharmaceuticals, Inc. today announced the presentation of data from its Phase 2b clinical trial with Aeroquin™ (a proprietary aerosol formulation of levofloxacin, MP-376) in cystic fibrosis (CF) at the American Thoracic Society (ATS) Annual Meeting in New Orleans.

17 May 2010

FDA grants NeoPharm's IL13-PE38QQR orphan-drug designation for treatment of IPF

NeoPharm, Inc., announced today that the Office of Orphan Products Development of the United States Food and Drug Administration (FDA) has granted orphan-drug designation for IL13-PE38QQR (IL13-PE) for the treatment of Idiopathic Pulmonary Fibrosis (IPF).

17 May 2010

Polypill to be tested in new heart disease trial

17 May 2010

High fat diet linked to exacerbation of asthma

In a new study researchers have found a connection between exacerbation of bronchial asthma and high calorie burgers and fries. Diet and lifestyle have been linked to asthma for some time now but this is the first real evidence. With the advent of unhealthy diets the incidence and prevalence of asthma is on the rise. In 2007, about 34.1 million Americans had asthma, according to the American Academy of Allergy, Asthma and Immunology. From 1980 through 1994, the prevalence of asthma increased by 75 percent.

17 May 2010

Lungs News and Research

Pearl Therapeutics presents data supporting development of PT003 combination bronchodilator product

Low blood phosphorus levels associated with high death rates in African AIDS patients: Research

CIHR experts discuss rising consumption of cigarettes among women

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

NAC therapy shows promise for patients with mild IPF

Oncolytics announces publication of Phase Ia/Ib U.K. clinical trial results of REOLYSIN for cancer

Immunetics receives $2.8M contract as part of NHLBI's REDS-II project

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

High school student studies effects of repeated x-rays in HMV children admitted for pneumonia

Study confirms genetic overlap for susceptibility to COPD and lung cancer

Cancer Research UK launches new cancer centre in Leeds

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

UMPIRE trial of Red Heart Pill launched to combat cardiovascular problems

Apnex HGNS System shows promising results in people suffering from OSA

FibroGen's FG-3019 human monoclonal antibody against CTGF reverses progression of lung fibrosis

WaferGen Biosystems first-quarter revenues increase to $389,785

Mpex Pharmaceuticals presents Phase 2b trial results of Aeroquin for cystic fibrosis at ATS Annual Meeting

FDA grants NeoPharm's IL13-PE38QQR orphan-drug designation for treatment of IPF

Polypill to be tested in new heart disease trial

High fat diet linked to exacerbation of asthma

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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