Antibodies News and Research

RSS

Does the duration between SARS-CoV-2 infection and vaccination affect immunity?

In a recent study posted to the medRxiv* preprint server, researchers at Oregon Health & Science University assessed the impact of the duration between coronavirus disease 2019 (COVID-19) infection and vaccination on immunity against infection.

8 Jan 2023

Pan-vaccine antigen strategy confers protection against cross-clade SARS-CoV-2 variants, including vaccine-resistant Omicron variants

Researchers developed a novel pan-vaccine antigen (Span)-based subunit vaccine against COVID-19.

6 Jan 2023

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Researchers investigated the reasons for the rapid advent of SARS-CoV-2 XBB.1.5, a sublineage of the Omicron recombinant mutant XBB in the USA.

6 Jan 2023

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Integral Molecular, the industry leader in antibody discovery for membrane proteins, has published the targeting mechanism enabling best-in-class specificity of its Claudin 6 (CLDN6) antibody CTIM-76 being developed for cancer therapy with Context Therapeutics.

6 Jan 2023

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

A recent study published in the journal Circulation examines the immunological picture in this scenario, looking for clues to the etiology of this rare and potentially serious complication.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Researchers conducted a multicenter, cross-sectional seroprevalence study in emergency departments of five hospitals in North Rhine-Westphalia, Germany, between August and September 2022. They assessed point seroprevalence and neutralization activity against Wu01, BA.4/5, and BQ.1.1.

5 Jan 2023

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

Researchers presented a microbody recombinant decoy protein with high affinity to angiotensin-converting enzyme 2 (ACE2) as an option for coronavirus disease 2019 (COVID-19) treatment.

5 Jan 2023

Public health agencies try to restore trust as they fight misinformation

By the summer of 2021, Phil Maytubby, deputy CEO of the health department here, was concerned to see the numbers of people getting vaccinated against covid-19 slipping after an initially robust response.

4 Jan 2023

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Researchers evaluated the seroprevalence and durability of antibodies against SARS-CoV-2 nucleocapsid protein among pregnant individuals and investigated transplacental antibody transfer.

3 Jan 2023

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

Researchers collaborated with community partners to monitor SARS-CoV-2 infections among domestic and free-ranging animals with known susceptibility to the virus and proximity to humans in Ohio, United States.

3 Jan 2023

What is the global state of SARS-CoV-2 seroprevalence in children?

Researchers conducted a systematic review to assess global pediatric SARS-CoV-2 seroprevalence.

3 Jan 2023

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

Researchers longitudinally evaluated humoral immune responses to the second and third doses of COVID-19 mRNA vaccines among individuals with and without prior history of SARS-CoV-2 infections.

3 Jan 2023

What is the impact of COVID-19 on the human genetic architecture?

Researchers recently described the second update on the study of human genetic architecture with respect to the effect of coronavirus disease 2019 (COVID-19).

3 Jan 2023

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

A new study in the journal Viruses examines the phenomenon of breakthrough infections due to the evasion of T-cell immunity by the Omicron BA.4/BA.5 subvariants, showing this to be due to spike gene mutations.

2 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

Antibodies News and Research

Does the duration between SARS-CoV-2 infection and vaccination affect immunity?

Pan-vaccine antigen strategy confers protection against cross-clade SARS-CoV-2 variants, including vaccine-resistant Omicron variants

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

Public health agencies try to restore trust as they fight misinformation

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

What is the global state of SARS-CoV-2 seroprevalence in children?

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

What is the impact of COVID-19 on the human genetic architecture?

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

Underlying genetic cause for MIS-C complications after COVID-19 identified

New method records gene activity patterns and presence of proteins across tissues

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Exploring T cell responses during COVID-19 breakthrough infection

Scientists explore synthesis of griffithsin in cell-free systems

How to make hybridoma-based antibody discovery more efficient eBook

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

Latest Life Science News