Transplant News and Research

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Researchers successfully transplant fully functional mini livers into rats

Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats.

2 Jun 2020

Ruxolitinib shows promise in severe COVID-19

An anti-inflammatory drug Ruxolitinib has shown promising results in the treatment of severe coronavirus disease COVID-19. The study titled, “Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial,” was published as a pre-proof for the Journal of Allergy and Clinical Immunology.

31 May 2020

New review analyzes appropriateness of off-pathway cancer care

Clinical oncology pathways are an important tool, helping cancer care providers and their patients to zero in on the most appropriate care plan.

30 May 2020

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

While breakthrough treatments have emerged for several cancers over the last two decades, driving striking improvements in survival and other clinical outcomes, too little is known about the risk of therapy-related hematologic cancers following targeted and immunotherapeutic approaches.

29 May 2020

Combination therapy does not show superior efficacy in newly diagnosed myeloma

The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not show superior efficacy in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care--bortezomib, lenalidomide, and dexamethasone (VRd).

29 May 2020

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by researchers at The University of Texas MD Anderson Cancer Center.

28 May 2020

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

Type 2 diabetes (T2D) affects American Indians and Alaska Natives at approximately three times the rate of white Americans and is closely linked to the disproportionately high rates of cardiovascular diseases such as heart attacks and strokes, according to the American Heart Association Scientific Statement "Cardiovascular Health in American Indians and Alaska Natives," published today in the Association's flagship journal Circulation.

28 May 2020

Scientists use microneedle patches to extract the skin’s interstitial fluid

The interstitial fluid is a major component of the liquid environment in the body and fills the spaces between the body's cells.

27 May 2020

Study finds very low level of SARS-CoV-2 in two San Francisco Bay areas

A new study published on the preprint server medRxiv in May 2020 reports a very low prevalence of antibodies in two separate populations living in the San Francisco Bay Area.

26 May 2020

Five important things to know about the new opt out organ donation law

From 20 May 2020, all adults in England are automatically considered potential organ donors following the introduction of the Organ Donation (Deemed Consent) Bill.

26 May 2020

Kidney transplants: Volume of services correlated with quality of treatment outcomes

In complex operations, is there a correlation between the volume of service provided per hospital and the quality of the treatment outcome? This question is addressed in eight commissions on minimum volumes that the Federal Joint Committee has issued to the Institute for Quality and Efficiency in Health Care.

22 May 2020

Study to examine how stem cell transplant patients react to COVID-19 infection

A new study will look at how patients, who receive stem cell transplants for blood cancers and blood disorders, react to COVID-19 infection during their recovery.

22 May 2020

Mount Sinai venture to develop and scale distribution of COVID antibody test kits

Mount Sinai Health System ("Mount Sinai") and Renalytix AI today announced the formation of Kantaro Biosciences, LLC ("Kantaro"), a Mount Sinai venture, to develop and scale production and distribution of a test kit based on the Mount Sinai-developed high-performance serologic assay for SARS-CoV-2 antibodies.

20 May 2020

Prellis Externalized Human Immune System produces human antibodies against SARS-Cov2

Prellis Biologics, Inc. today announced that it has generated 300 human IgG antibodies that bind to either the S1 or S2 spike protein of the SARS-CoV2-Wuhan strain of the novel coronavirus.

20 May 2020

MGH researchers identify potential molecular targets for ALD drug development

Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant.

19 May 2020

Fewer traffic collisions during shutdown means longer waits for organ donations

On Day Two of the San Francisco Bay Area's stay-at-home orders in March, Nohemi Jimenez got into her car in San Pablo, California, waved goodbye to her 3-year-old son and drove to her regular Wednesday dialysis appointment.

19 May 2020

Oxford Immunotec releases the T-SPOT® Discovery™ SARS-CoV-2 kit

Oxford Immunotec Global PLC, a global, high-growth diagnostics company, today announces the release of the T-SPOT Discovery SARS-CoV-2 test kit.

19 May 2020

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Takeda Pharmaceutical Company Limited today announced that the company will present data from its expanding oncology pipeline and established product portfolio at two upcoming virtual scientific congresses: the 56th Annual Meeting of the American Society of Clinical Oncology, May 29-31 and the 25th Virtual Congress of the European Hematology Association, June 11-14.

18 May 2020

COVID-19 patients at high risk for developing complications associated with blood clots

When researchers from the University of Colorado Anschutz Medical Campus, Aurora, used a combination of two specific blood-clotting tests, they found critically ill patients infected with Coronavirus Disease 2019 (COVID-19) who were at high risk for developing renal failure, venous blood clots, and other complications associated with blood clots, such as stroke.

15 May 2020

University of Greenwich develops compounds that can fight COVID-19 killer

Covid-19 treatment that could potentially also help protect cancer and organ transplant patients is being developed at the University of Greenwich.

15 May 2020

Transplant News and Research

Researchers successfully transplant fully functional mini livers into rats

Ruxolitinib shows promise in severe COVID-19

New review analyzes appropriateness of off-pathway cancer care

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

Scientists use microneedle patches to extract the skin’s interstitial fluid

Study finds very low level of SARS-CoV-2 in two San Francisco Bay areas

Five important things to know about the new opt out organ donation law

Kidney transplants: Volume of services correlated with quality of treatment outcomes

Study to examine how stem cell transplant patients react to COVID-19 infection

Mount Sinai venture to develop and scale distribution of COVID antibody test kits

Prellis Externalized Human Immune System produces human antibodies against SARS-Cov2

MGH researchers identify potential molecular targets for ALD drug development

Fewer traffic collisions during shutdown means longer waits for organ donations

Oxford Immunotec releases the T-SPOT® Discovery™ SARS-CoV-2 kit

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

COVID-19 patients at high risk for developing complications associated with blood clots

University of Greenwich develops compounds that can fight COVID-19 killer

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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