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New drug shows promise to treat women with estrogen positive metastatic breast cancer

Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease.

31 Aug 2017

Experimental drug isolated from tick saliva may hold promise for reducing HIV-linked heart disease risk

Scientists may have found a clue to why people living with HIV have double the likelihood of developing heart disease.

30 Aug 2017

New discovery reveals gut bacteria and human cells speak the same chemical language

We have a symbiotic relationship with the trillions of bacteria that live in our bodies--they help us, we help them. It turns out that they even speak the same language.

30 Aug 2017

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

Cancer cells obtained from a blood test may be able to predict how early-stage lung cancer patients will fare, a team from the University of Michigan has shown.

30 Aug 2017

HHMI scientists expand access to new resource for studying pediatric cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

30 Aug 2017

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Rugby players from Aviva Premiership Rugby and Greene King IPA Championship are to take part in a major study led by the University of Birmingham as part of its work to develop a ground-breaking pitch-side test to diagnose concussion and brain injury.

30 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

Study links psoriasis severity to increased risk of death

The more the surface area of the body is covered by psoriasis, the greater the risk of death for the patient suffering from the condition, according to a new analysis by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Aug 2017

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

Age-related memory loss may be reversed by boosting blood levels of osteocalcin, a hormone produced by bone cells, according to mouse studies led by Columbia University Medical Center researchers.

29 Aug 2017

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Is telomere length associated with the cognitive response to a lifestyle intervention? Supporting evidence from the FINGER trial.

29 Aug 2017

SBP scientist receives DoD award to identify new and efficacious treatments for pancreatic cancer

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce that the Department of Defense (DoD) has awarded Cosimo Commisso, Ph.D., a Career Development Award to identify new and efficacious treatments for pancreatic cancer.

29 Aug 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

The long-term use of over-the-counter (OTC) anti-inflammatory drugs can inhibit muscle growth in young, healthy individuals engaging in weight training, according to a new study from Karolinska Institutet, reporting on the effects of ibuprofen on the skeletal muscles and published in Acta Physiologica.

28 Aug 2017

Substitution of gasoline for ethanol in dual-fuel vehicles increases level of polluting nanoparticles

When ethanol prices at the pump rise for whatever reason, it becomes economically advantageous for drivers of dual-fuel vehicles to fill up with gasoline.

28 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

Vision research using donated human tissue could help millions suffering from diabetic eye disease

When Coleen Anegon's husband, Tim, received a liver donation as a patient at the University of Michigan in 2014, she immediately felt indebted to the donor who gave him the gift of life.

26 Aug 2017

Distinguishing biothreat look-alikes could aid biological surveillance

Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.

26 Aug 2017

Rutgers University leadership creates great strides in breakthrough scientific research

Less than a decade ago, the U.S. Department of Defense established the Armed Forces Institute of Regenerative Medicine I with a multimillion dollar grant to focus research centered on regenerative medicine for the treatment of battlefield injuries and selected Rutgers University-New Brunswick to lead the civilian research program.

26 Aug 2017

Women with history of pre-eclampsia more likely to face atherosclerosis decades after pregnancy

A new study has found that a condition that threatens the lives of some pregnant women and the fetus may continue to put the mother at risk later in life.

26 Aug 2017

Laboratory News and Research

New drug shows promise to treat women with estrogen positive metastatic breast cancer

Experimental drug isolated from tick saliva may hold promise for reducing HIV-linked heart disease risk

New discovery reveals gut bacteria and human cells speak the same chemical language

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

HHMI scientists expand access to new resource for studying pediatric cancers

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Study links psoriasis severity to increased risk of death

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

SBP scientist receives DoD award to identify new and efficacious treatments for pancreatic cancer

Research reveals LEGO-like stacking of protein complexes

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

Substitution of gasoline for ethanol in dual-fuel vehicles increases level of polluting nanoparticles

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

Vision research using donated human tissue could help millions suffering from diabetic eye disease

Distinguishing biothreat look-alikes could aid biological surveillance

Rutgers University leadership creates great strides in breakthrough scientific research

Women with history of pre-eclampsia more likely to face atherosclerosis decades after pregnancy

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