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Poniard Pharmaceuticals reports net loss of $13.2M for fourth-quarter 2009

Poniard Pharmaceuticals, Inc., a biopharmaceutical company focused on innovative oncology therapies, today reported financial results for the fourth quarter and year ended December 31, 2009.

8 Mar 2010

Scientists succeed in mapping entire network of DNA-binding transcription factors

In a significant leap forward in the understanding of how specific types of tissue are determined to develop in mammals, an international team of scientists has succeeded in mapping the entire network of DNA-binding transcription factors and their interactions. This global network, indicating which factors can combine to determine cell fate, will be published in the March 5 issue of the journal Cell.

6 Mar 2010

Research group performs randomized study to evaluate efficacy of ICCBco in treatment of lung lesions

To evaluate efficacy of Calculus Bovis compound preparation (ICCBco) in the treatment of lung lesions in portal hypertensive rabbits with schistosomiasis as the experimental animal model, a research group in China performed a randomized, double-blind, controlled trial to observe pathological changes and pathological effect mechanism of expression of fibronectin and laminin in the lung tissue of portal hypertensive rabbits with schistosomiasis.

6 Mar 2010

Abt Associates receives two new contracts to evaluate effectiveness of H1N1 vaccine

The Centers for Disease Control and Prevention has awarded Abt Associates two new contracts to evaluate the effectiveness of the H1N1 vaccine among health care workers and children under the age of 18.

6 Mar 2010

Postoperative complications more likely to occur at low-volume institutions

The frequency of post-operative complications following surgery for liver cancer is associated with a hospital having a low volume of liver surgery. Investigators at The Cancer Institute of New Jersey (CINJ) are presenting that finding at the 63rd Annual Society of Surgical Oncology Symposium taking place this week in St. Louis. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

6 Mar 2010

Humanetics' BIO 300 medical radiation countermeasure drug candidate issued U.S. patent

In an announcement today, Humanetics Corporation reported that its BIO 300 medical radiation countermeasure drug candidate has been issued a U.S. patent. The patent is assigned to the United States of America with Humanetics as the designated licensee.

5 Mar 2010

Varicose veins may signal potential dangerous blood clots

March is DVT Awareness Month and Vein Clinics of America encourages people with varicose veins, particularly those that have become painful and inflamed, to visit a vein specialist.

5 Mar 2010

FDA's PADAC meeting to review pirfenidone NDA: InterMune posts briefing documents

InterMune, Inc. announced today that the U.S. Food and Drug Administration (FDA) has posted briefing documents for the March 9 Pulmonary-Allergy Drugs Advisory Committee (PADAC) meeting to review the New Drug Application (NDA) for pirfenidone, InterMune's investigational drug candidate for the treatment of patients with idiopathic pulmonary fibrosis (IPF) to reduce decline in lung function. The proposed trade name for pirfenidone is Esbriet®.

5 Mar 2010

UC researchers find CT scan screening of non-smoking women is cost-effective

Researchers at the University of Cincinnati have found that it is cost-effective to do CT scan screening of non-smoking women, ages 25-54, who come to the emergency room for the first time with a collapsed lung in order to diagnose and treat those with lymphangioleiomyomatosis, or LAM.

5 Mar 2010

Men should discuss risks, benefits with doctor before undergoing prostate-cancer screening

Men who undergo prostate-cancer screening should discuss with a doctor the uncertainties, risks and benefits of the test before it is performed, says Edward Partridge, M.D., president-elect of the American Cancer Society National Board of Directors and director of the University of Alabama at Birmingham Comprehensive Cancer Center.

5 Mar 2010

Endothelial cells can produce copious amounts of adult stem cells: Study

In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks.

5 Mar 2010

TransMedics closes $36M financing round

TransMedics, Inc., a leading medical device company focusing on delivering the next standard of care for solid organ transplantation worldwide, announced today the closing of a $36 million financing round. The financing was lead by Foundation Capital and Kleiner Perkins Caufield & Byers (KPCB) and also included investments by Flagship Ventures and by several existing investors.

5 Mar 2010

bioTheranostics launches CancerTYPE ID database and KRAS mutational testing

bioTheranostics, a bioMerieux company that discovers, develops and commercializes innovative molecular diagnostic tests in oncology, announces the launch of an expanded tumor-type database for its flagship product, CancerTYPE ID®, and the launch of KRAS mutational testing.

5 Mar 2010

Leading experts to discuss latest pharmacogenomic research at European Lung Cancer Conference

Rapid advances in drug development, genetics and multidisciplinary treatment have brought the field of oncology to a critical moment, says Dr. Rafael Rosell from the Catalan Institute of Oncology in Badalona, Spain, co-chair of the second European Lung Cancer Conference (ELCC), which will be held in Geneva, Switzerland from 28 April to 1 May 2010.

4 Mar 2010

Using high-resolution CT-scans to screen for LAM is cost-effective in non-smoking women

Researchers at the University of Cincinnati have found that using high-resolution CT-scans to screen for lymphangioleiomyomatosis, or LAM, is cost-effective in non-smoking women between 25 and 54 who come to the emergency room for the first time with a collapsed lung.

4 Mar 2010

Philadelphia FRESH project: Door to door smoking cessation treatment for smokers with young children

In underserved areas like North Philadelphia, existing research shows a nearly 10 percent higher smoking rate than in the general population, with a lower quit rate to boot. The consequences of this public health problem are magnified for new mothers that smoke, as they also expose their babies to the ill effects of second-hand smoke.

4 Mar 2010

Cryoablation kills breast tumors in mice

Freezing a cancer kills it in its place, and also appears to generate an immune response that helps stop the cancer's spread, leading to improved survival rates over surgery, according to a new study in mice from researchers at the University of Michigan Comprehensive Cancer Center.

4 Mar 2010

Abbott enters into agreement with GSK to develop molecular diagnostic test for skin cancer treatment

Abbott announced today that it has entered into an agreement with GlaxoSmithKline (GSK) to develop a molecular diagnostic test intended for use as an aid in selecting patients who may benefit from a skin cancer treatment in development by GSK.

4 Mar 2010

St. Jude Medical publishes clinical results of HOMEOSTASIS trial

St. Jude Medical, Inc. today announced publication of clinical results in the Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS) trial.

4 Mar 2010

Biomoda and Amigenics collaborate to advance treatments for lung and other cancer

Biomoda, Inc. (www.biomoda.com) and Advanced Medical Imaging and Genetics (www.amigenics.com), an innovative medical clinic specializing in prevention and early detection of disease, announced their intent to collaborate on a variety of projects to advance technology for the early detection of lung and other cancer.

4 Mar 2010

Lungs News and Research

Poniard Pharmaceuticals reports net loss of $13.2M for fourth-quarter 2009

Scientists succeed in mapping entire network of DNA-binding transcription factors

Research group performs randomized study to evaluate efficacy of ICCBco in treatment of lung lesions

Abt Associates receives two new contracts to evaluate effectiveness of H1N1 vaccine

Postoperative complications more likely to occur at low-volume institutions

Humanetics' BIO 300 medical radiation countermeasure drug candidate issued U.S. patent

Varicose veins may signal potential dangerous blood clots

FDA's PADAC meeting to review pirfenidone NDA: InterMune posts briefing documents

UC researchers find CT scan screening of non-smoking women is cost-effective

Men should discuss risks, benefits with doctor before undergoing prostate-cancer screening

Endothelial cells can produce copious amounts of adult stem cells: Study

TransMedics closes $36M financing round

bioTheranostics launches CancerTYPE ID database and KRAS mutational testing

Leading experts to discuss latest pharmacogenomic research at European Lung Cancer Conference

Using high-resolution CT-scans to screen for LAM is cost-effective in non-smoking women

Philadelphia FRESH project: Door to door smoking cessation treatment for smokers with young children

Cryoablation kills breast tumors in mice

Abbott enters into agreement with GSK to develop molecular diagnostic test for skin cancer treatment

St. Jude Medical publishes clinical results of HOMEOSTASIS trial

Biomoda and Amigenics collaborate to advance treatments for lung and other cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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