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New kidney test better elder mortality predictor

A study at the San Francisco VA Medical Center (SFVAMC) has found that a test of kidney function that measures blood levels of cystatin C -- a protein produced by most cells in the body -- is a far more accurate predictor of mortality risk in elderly people than the current standard kidney function test, which measures levels of the protein creatinine.

20 May 2005

Disease progression model of pancreatic cancer developed

Building on previous work, researchers at the University of Pennsylvania School of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to develop new treatments for this deadly disease.

20 May 2005

Women are particularly vulnerable to the harmful effects of excessive drinking

A brain-scan study in Germany has found evidence that women are particularly vulnerable to the harmful effects of excessive drinking.

17 May 2005

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Oral Hormone Replacement Therapy (HRT) seems to have a beneficial impact on cardiovascular health in hypertensive postmenopausal women, researchers reported at the American Society of Hypertension Twentieth Annual Meeting held in San Francisco.

16 May 2005

Disabling gene defuses rheumatoid arthritis in mice

Scientists studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves from the inflammatory chemicals they secrete.

16 May 2005

Women more vulnerable to chronic drinking than men are

A study in the May issue of Alcoholism: Clinical & Experimental Research addresses this gap in research, using computed tomography (CT) to examine brain atrophy in the brains of alcoholic men and women. The findings support and build upon a prior hypothesis that women develop alcohol-related brain damage more readily than men.

16 May 2005

Botox injections decrease drooling in children with neurologic impairments

Ultrasound-guided Botox injections into the salivary glands decrease drooling in children with neurologic impairments such as cerebral palsy, say researchers from Toronto’s Hospital for Sick Children.

16 May 2005

Surgical technique provides the first permanent solution to treating vocal-cord spasms

The first large, long-term study of patients who had surgery to control vocal-cord spasms showed excellent results in the majority of cases, reports new UCLA research presented May 14 at the 126th Annual Meeting of the American Laryngological Association.

15 May 2005

Commonly used drugs raise the risk of cardiac problems

As many as 15,000 sudden deaths each year in Europe and the U.S., may be caused by drugs commonly prescribed for psychiatric and gut disorders.

11 May 2005

Call for "ring-fenced" funds for research into Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (ME/CFS)

The medical research charity, MERGE (ME Research Group) is calling for the ring fencing of resources for biomedical research into ME/CFS.

11 May 2005

Increased risk of sudden cardiac death from some non-cardiac drugs

Non-cardiac drugs that interfere with the electrical activity controlling the heartbeat are associated with a three-fold risk of sudden cardiac death, according to Dutch research published (Wednesday 11 May) in Europe's leading cardiology journal, the European Heart Journal.

11 May 2005

Obesity appears to worsen and possibly cause asthma

Obesity is a known risk factor for type II diabetes, heart disease and some forms of cancer. Evidence is now mounting that obesity is also a risk factor for asthma.

10 May 2005

Study calls for earlier use of ICDs in patients diagnosed with cardiomyopathy

A study presented today at the Late Breaking Clinical Trials presentations at the Heart Rhythm Society's Annual Scientific Sessions in New Orleans found that implantable cardiac defibrillators (ICD) benefit patients with recently diagnosed cardiomyopathy, a disease that affects the heart muscle's ability to pump and can lead to heart failure.

8 May 2005

Scientists extend the lifespan of mice

Scientists at the University of Washington and their colleagues at other research centers have found a way to significantly extend the lifespan of mice while reducing the impact of the aging process. Their study, which will be published online by the journal Science on May 5, lends more credence to the free-radical theory of aging.

5 May 2005

Neutrophils dictate whether our immune system will permit or prevent bacterial infections

New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists' belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections.

5 May 2005

Cancer hijacks normal wound-healing processes

Scientists have known for the last decade that a link exists between wound healing and cancer. For instance, in a 1994 experiment at the Lawrence Berkeley National Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding.

5 May 2005

Abnormal heart scans predict higher risks for African-Americans and Hispanics

SPECT imaging scans show that abnormalities in blood flow to the muscle of the heart indicate higher cardiovascular disease risk in African-Americans and Hispanics than similar abnormalities in white patients, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Mutated gene causes serious heart disease in newborns

The research group of professor Manfred Kilimann at the Department of Cell and Molecular Biology has elucidated the genetic cause of a severe heart disease in newborn children. This result will be published in the June issue of the American Journal of Human Genetics this week.

3 May 2005

Researchers have successfully induced adult heart-muscle cells to divide and multiply

In the best documented effort to date, researchers from the Howard Hughes Medical Institute at Children's Hospital Boston and Harvard Medical School have successfully induced adult heart-muscle cells to divide and multiply.

3 May 2005

Critical lock and key mechanism found for the assembly of tumor blood vessels

A critical lock and key mechanism that allows the final step in the completion of new blood vessel formation has been identified by a University of California, San Diego (UCSD) School of Medicine team in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply.

3 May 2005