Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

The European Laboratory Research & Innovation Group UK and the British Pharmacological Society, announced today that they have formed a strategic alliance.

17 Dec 2019

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson's disease finds that it is reasonably safe and well tolerated.

17 Dec 2019

Seafood consumption and mercury concentrations in vulnerable coastal Florida population

Mercury contamination of the marine environment is a global public health concern. Human exposure occurs primarily by eating seafood, especially large predatory fish such as swordfish and albacore tuna.

16 Dec 2019

Human genetics evidence predictive of drug development success, study shows

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts.

From PLOS ONE 13 Dec 2019

New software to help researchers study specific information about proteins

What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body?

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Stilla Technologies announces key leadership hires

Stilla Technologies, the provider of pioneering digital PCR solutions for high-precision genetic analysis, today announced three key hires: Khaled Bahi joins as CFO, with Jerome Leclercq named Senior Vice President for Commercial Operations Europe & Asia and Quang Tran named Quality & Regulatory Affairs Director.

11 Dec 2019

Experts say cancer research is making more progress that people think

The focus on a “cure for cancer” is masking progress made in extending lifespan and making cancer manageable in the long-term.

9 Dec 2019

Intellegens and Optibrium announce success in the Open Source Malaria global initiative

Intellegens, an artificial intelligence start-up, and, Optibrium, leading providers of software and services for drug discovery, today announced joint success in the Open Source Malaria global initiative aimed at identifying the best predictive models for antimalarial compounds.

6 Dec 2019

Biosero and RORZE Lifescience collaborate to commercialize Green Button Go Automation Scheduling Software in Asia

Biosero, Inc. announced a new partnership wherein RORZE Lifescience, Inc., a subsidiary of Rorze, Inc., will commercialize Biosero’s Green Button Go Automation Scheduling Software in Asia.

From Biosero Inc. 6 Dec 2019

Coriell scientist awarded grant to explore epigenetic drivers of breast cancer

Shoghag Panjarian, PhD, a research scientist at the Coriell Institute for Medical Research, has been awarded a grant from the W. W. Smith Charitable Trust to support her search for epigenetic factors that contribute to the development and growth of breast cancer.

5 Dec 2019

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

House Speaker Nancy Pelosi's flagship proposal to curb prescription drug prices, the "Lower Drug Costs Now Act" - H.R. 3 - could come up for a vote in the chamber this month.

5 Dec 2019

Georgia State professor selected as National Academy of Inventors Fellow

Jenny Yang, a Regents' Professor of chemistry at Georgia State University and the associate director of the Center for Diagnostics and Therapeutics, has been selected as a National Academy of Inventors (NAI) Fellow, the academy board announced on Tuesday.

5 Dec 2019

ADDF announces new awards through its Diagnostics Accelerator initiative

The Alzheimer's Drug Discovery Foundation announced six new investments totaling $6 million through its Diagnostics Accelerator initiative.

4 Dec 2019

Newly developed cell models can open up new avenues for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which have many benefits over the models currently used by researchers and pharmaceutical companies. The models were developed by Professor Arto Urtti's Ocular Drug Delivery group at the University of Eastern Finland.

4 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Metrion Biosciences Limited, the specialist ion channel CRO and drug discovery company, and LifeArc, a leading UK independent medical research charity, today announced an extension of their neuroscience-focused ion channel drug discovery collaboration, following the success of the initial twelve-month agreement.

From Metrion Biosciences Limited 4 Dec 2019

Scientist earns prestigious award for research into cell suicide

Apoptosis is a form of “cell suicide”, where a cell self-terminates, ideally as planned or programmed, enabling multi-cellular organisms to continue to live, develop and thrive.

4 Dec 2019

Drug Discovery News and Research

Further Reading

Combined datasets can expedite the discovery and development of new cancer drugs

A new book on ovarian cancer

ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

Seafood consumption and mercury concentrations in vulnerable coastal Florida population

Human genetics evidence predictive of drug development success, study shows

New software to help researchers study specific information about proteins

Experimental Alzheimer’s drugs show promise

Stilla Technologies announces key leadership hires

Experts say cancer research is making more progress that people think

Intellegens and Optibrium announce success in the Open Source Malaria global initiative

Biosero and RORZE Lifescience collaborate to commercialize Green Button Go Automation Scheduling Software in Asia

Coriell scientist awarded grant to explore epigenetic drivers of breast cancer

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

Georgia State professor selected as National Academy of Inventors Fellow

ADDF announces new awards through its Diagnostics Accelerator initiative

Newly developed cell models can open up new avenues for ocular drug discovery

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

Metrion and LifeArc extend neuroscience-focused ion channel drug discovery collaboration

Scientist earns prestigious award for research into cell suicide

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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