Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Cambridge scientists develop new method for growing and transplanting artificial bile ducts

Cambridge scientists have developed a new method for growing and transplanting artificial bile ducts that could in future be used to help treat liver disease in children, reducing the need for liver transplantation.

3 Jul 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

A new study has uncovered low rates of referral for palliative care in US patients with end-stage liver disease, although rates have been slowly increasing over time.

29 Jun 2017

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Discovered more than two decades ago, the hormone leptin has been widely hailed as the key regulator of leanness. Yet, the pivotal experiments that probe the function of this protein and unravel the precise mechanism of its action as a guardian against obesity are largely missing.

24 Jun 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Abbott introduces Sekisui CP3000 fully automated coagulation system for accurate test results

Today, Abbott announced that the Sekisui CP3000 coagulation system, a fully automated analyzer that tests bleeding and clotting function in blood, is now available in Europe, the Middle East, and Asia Pacific.

23 Jun 2017

Excess male hormones in PCOS women contribute to metabolic complications, study shows

Scientists from the University of Birmingham have discovered the link between increased male hormones and metabolic complications such as diabetes and fatty liver disease in patients with polycystic ovary syndrome.

23 Jun 2017

ISU entomologist urges summertime precautions against mosquitoes and ticks

Ryan Smith, an assistant professor of entomology at Iowa State University is encouraging Iowans to take precautions this summer when spending time outdoors in areas commonly populated by mosquitoes and ticks, which can transmit West Nile virus and other diseases that can have serious or potentially fatal outcomes.

22 Jun 2017

Popular prostate drug has negative impact on men's overall health, study suggests

Treatment of benign prostatic hyperplasia (BPH) with the commonly prescribed Avodart (Dutsteride) may put men at an increased risk for diabetes, elevated cholesterol levels, non-alcoholic fatty liver disease (NAFLD) and worsening erectile dysfunction.

22 Jun 2017

Researchers bioengineer human liver tissues that mimic natural development

An international team of researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ's developmental processes – greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells.

15 Jun 2017

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Saint Louis University researchers report in Molecular Metabolism new findings that the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries.

14 Jun 2017

Monounsaturated fats promote fatty liver disease, study finds

As the obesity epidemic continues, new data shed light on which nutrients and what quantity of those nutrients promote health or disease.

14 Jun 2017

Study finds link between breastfeeding duration, maternal obesity and NAFLD in adolescents

Infants who were breastfed for less than six months before starting infant formula milk and infants who had mothers who were obese at the start of pregnancy, were much more likely to develop nonalcoholic fatty liver disease (NAFLD) as adolescents, according to a novel study in the Journal of Hepatology.

12 Jun 2017

UNC researchers identify how class of antiviral drugs interacts with HCV

Globally, an estimated 71 million people are living with chronic hepatitis C virus (HCV). Over decades of infection, chronic HCV infection results in progressive damage to the liver and an increased risk for end stage liver disease and liver cancer, making the virus the leading cause of liver-related deaths in the United States today.

9 Jun 2017

SLU scientist discovers cause and potential solution for cancer-related bone pain

In a paper published in the journal Pain, Saint Louis University researcher Daniela Salvemini, Ph.D., reports discovering a key molecular pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market.

8 Jun 2017

Natural sugar may trigger immune system to treat atherosclerosis, study finds

Researchers have long sought ways to harness the body's immune system to treat disease, especially cancer.

7 Jun 2017

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Chronic liver diseases rank as the 12th cause of death worldwide and many of these disorders are associated with unhealthy lifestyles. Conversely, a healthier lifestyle can help prevent or reverse liver disease.

6 Jun 2017

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

Patients who undergo the Fontan operation as children for a complex congenital heart defect are at risk of developing progressive liver fibrosis, a buildup of fibrous deposits, as a result of the circulation created by the surgery, according to a new study.

31 May 2017

New drug offers hope to patients with hepatitis C

Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.

26 May 2017

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

Disruptions in a protein folding process occurring in the brain, known as endoplasmic reticulum (ER) stress, may cause non-alcoholic fatty liver disease, independent of other factors. A research team at the George Washington University published their results in the Journal of Clinical Investigation Insight.

25 May 2017

Liver Disease News and Research

Further Reading

Cambridge scientists develop new method for growing and transplanting artificial bile ducts

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

Scientists find lack of experimental evidence detailing biologic roles of leptin in metabolism

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

Abbott introduces Sekisui CP3000 fully automated coagulation system for accurate test results

Excess male hormones in PCOS women contribute to metabolic complications, study shows

ISU entomologist urges summertime precautions against mosquitoes and ticks

Popular prostate drug has negative impact on men's overall health, study suggests

Researchers bioengineer human liver tissues that mimic natural development

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Monounsaturated fats promote fatty liver disease, study finds

Study finds link between breastfeeding duration, maternal obesity and NAFLD in adolescents

UNC researchers identify how class of antiviral drugs interacts with HCV

SLU scientist discovers cause and potential solution for cancer-related bone pain

Natural sugar may trigger immune system to treat atherosclerosis, study finds

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

New drug offers hope to patients with hepatitis C

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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