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Human Genome Sciences reports results of phase 2b trial of Albuferon

Human Genome Sciences has reported results at Week 12 following the completion of therapy (SVR12) in a Phase 2b clinical trial of Albuferon(R) (albinterferon alfa-2b) in combination with ribavirin in patients with genotype 1 chronic hepatitis C who are naive to interferon alpha-based treatment regimens.

16 Apr 2007

deCODE launches novel DNA-based reference laboratory test for assessing inherited risk of type 2 diabetes

deCODE genetics has announced the launch of deCODE T2, a novel DNA-based reference laboratory test for the first common and well-validated genetic risk factor for type 2 diabetes (T2D).

16 Apr 2007

Mapping rhesus macaque genome helps illuminate what makes us human

Researchers have sequenced the genome of the relatively ancient rhesus macaque ( Macaca mulatta ), providing perspective into how humans are genetically different from our primate relatives.

15 Apr 2007

People with two copies of a particular gene have a 70% higher risk of being obese

Scientists have identified the most clear genetic link yet to obesity in the general population as part of a major study of diseases funded by the Wellcome Trust, the UK's largest medical research charity.

15 Apr 2007

Macaque genome analysis will improve scientists' ability to identify human genes involved in diseases

Cornell experts in computational biology and bioinformatics have made key contributions to the analysis of the genome of the rhesus macaque, better known as the rhesus monkey.

15 Apr 2007

LaeA gene shown to be an ideal prospect for new ways to fight infection

For the growing number of people with diminished immune systems - cancer patients, transplant recipients, those with HIV/AIDS - infection by a ubiquitous mold known as Aspergillus fumigatus can be a death sentence.

15 Apr 2007

Understanding of primate evolution advanced

The completed DNA sequence of the rhesus macaque ,an Old World monkey, has advanced understanding of primate evolution and will enhance medical research in neuroscience, behavioral biology, reproductive physiology, endocrinology, heart and blood vessel disease and immunodeficiency, said scientists at the Baylor College of Medicine (BCM) Human Genome Sequencing Center who led the effort.

15 Apr 2007

First successful attempt to determine the structure of RfaH transcription factor

The results of a new study suggest that bacteria that cause diseases like bubonic plague and serious gastric illness can turn the genes that make them infectious on or off.

15 Apr 2007

Analysis of Rhesus monkey genome provides new clues to primate biology

An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes.

12 Apr 2007

Study identifies clearest link yet to obesity risk

12 Apr 2007

Massive gene screening points way to more effective chemotherapy

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

12 Apr 2007

Transgenomic signs contract with OSI Pharmaceuticals for cancer genetic analysis

Transgenomic has announced that it has signed a contract with OSI Pharmaceuticals to complete an analysis of specific cancer pathway genes.

11 Apr 2007

Genetic mutation that prevents sperm production found

Up to 15 percent of couples of childbearing age struggle with the heartache of infertility.

11 Apr 2007

Vitiligo gene linked to other autoimmune diseases

In a study appearing in the March 22 New England Journal of Medicine, scientists supported by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have discovered a connection between a specific gene and the inflammatory skin condition vitiligo, as well as a possible host of autoimmune diseases.

11 Apr 2007

Scientists decode genome of Streptococcus sanguinis

Virginia Commonwealth University researchers have decoded the genome of a bacteria normally present in the healthy human mouth that can cause a deadly heart infection if it enters the bloodstream.

7 Apr 2007

Geometry of viruses

A mathematician at the University of York has been awarded a Research Leadership Award of more than ,700,000 by the Leverhulme Trust to study the geometry of viruses.

4 Apr 2007

Researchers identify 221 genes possibly related to addiction vulnerability

Scientists supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, have for the first time identified genes that might increase a person's ability to abstain from smoking.

4 Apr 2007

New blood test to rapidly detect levels of radiation exposure

In the event of a nuclear or radiological catastrophe -- such as a nuclear accident or a "dirty bomb" -- thousands of people would be exposed to radiation, with no way of quickly determining how much of the deadly substance has seeped inside their bodies.

4 Apr 2007

Rabies vaccine approach against HIV shows promise

Rabies, a relentless, ancient scourge, may hold a key to defeating another implacable foe: HIV. Scientists at Jefferson Medical College in Philadelphia have used a drastically weakened rabies virus to ferry HIV-related proteins into animals, in essence, vaccinating them against an AIDS-like disease.

3 Apr 2007

Chromosomal microarray analysis accurately detects abnormalities in individual chromosomes

Two years and more than 2,000 samples after researchers at Baylor College of Medicine started to use a new gene-chip technology called chromosomal microarray analysis to look for potential genetic abnormalities in children, they find that it is remarkably sensitive in detecting abnormalities in individual chromosomes, according to a report that appears online today in the journal Public Library of Science ONE.

2 Apr 2007