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FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

New study finds dramatic reorganization of the gut caused by weight loss surgery

Obesity, already a global epidemic, is on the rise. Over one-third of the U.S. population is currently afflicted, according to the Centers for Disease Control and the monetary costs alone are approaching $150 billion dollars annually.

26 May 2017

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

Botulinum neurotoxin is probably best known to Americans as BOTOX, a cosmetic medicine, rather than as a cause of potentially dangerous foodborne illnesses.

26 May 2017

New NMR machine at TSRI’s Florida campus will help advance drug development process

The Nuclear Magnetic Resonance facility at the Florida campus of The Scripps Research Institute is becoming one of the most advanced in South Florida, thanks to a new $600,000 grant from the National Institutes of Health.

26 May 2017

Gray matter density increases during transition from childhood to young adulthood, study reveals

For years, the common narrative in human developmental neuroimaging has been that gray matter in the brain - the tissue found in regions of the brain responsible for muscle control, sensory perception such as seeing and hearing, memory, emotions, speech, decision making, and self-control -- declines in adolescence, a finding derived mainly from studies of gray matter volume and cortical thickness (the thickness of the outer layers of brain that contain gray matter).

26 May 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Scientists identify genetic risk factor for equine squamous cell carcinoma

Squamous cell carcinoma (SCC) is the most common cancer found in equine eyes and the second most common tumor of the horse overall. Thanks to a recent genetic study led by UC Davis, horse owners can now identify horses at risk for ocular SCC and make informed breeding decisions.

25 May 2017

Mettler Toledo GWP verification helps pharmaceutical company decide on weighing equipment

For more than 200 years, the German-based company Klosterfrau Healthcare Group has been developing, manufacturing and selling pharmaceutical products. Its portfolio combines traditional remedies with modern drug therapies and encompasses more than 30 brands and nearly 220 over-the-counter products.

25 May 2017

Study finds wearable fitness trackers accurately measure heart rate but not energy expenditure

According to a study published online in the Journal of Personalized Medicine, fitness activity trackers measure heart rates precisely but not the number of calories burned.

25 May 2017

High quality microplate readers built to last decades by German manufacturer BMG Labtech

From the outset BMG LABTECH’s mission was to develop microplate readers guaranteed to provide optimum performance for years. BMG LABTECH has continued this philosophy while continuing to remain at the forefront of microplate reading, always introducing innovative and unique technologies. All microplate readers are built to be extremely reliable and robust over decades, some of BMG LABTECH’s very first products are still in use across the globe.

25 May 2017

Near real-time genomic sequencing reveals how Zika virus entered into the U.S.

A new study by a multi-national research team, including scientists from the U.S. Army Medical Research Institute of Infectious Diseases, explains how Zika virus entered the United States last year and how it might re-enter the country this year.

25 May 2017

Molecule discovered in worm spit could offer solution for non-healing wounds

Every day 12 Australian diabetics have a limb amputated because of a non-healing wound. Globally, it's one every 30 seconds.

25 May 2017

Yearlong study creates detailed map of microbial colonization in a newly opened hospital

A 12-month study mapping bacterial diversity within a hospital -; with a focus on the flow of microbes between patients, staff and surfaces -; should help hospitals worldwide better understand how to encourage beneficial microbial interactions and decrease potentially harmful contact.

24 May 2017

Drug-related cues increase craving, dopamine release in the brain of recreational cocaine users

Even among non-dependent cocaine users, cues associated with consumption of the drug lead to dopamine release in an area of the brain thought to promote compulsive use, according to researchers at McGill University.

24 May 2017

Isolera™ Dalton 200 intelligent sampling device released by Biotage

Isolera™ Dalton 2000 is seamlessly integrated with Isolera™ Spektra flash purification system via the Isolera™ Dalton Nanolink unit, an intelligent sampling device which handles all fluids and synchronization between the two instruments.

From Biotage Sweden AB 24 May 2017

New test could help physicians identify appropriate treatment for people with gonorrhea

Researchers from UCLA have developed a laboratory test that helps physicians determine which people with gonorrhea may be more treatable with an antibiotic that has not been recommended since 2007 because of concerns that the resistance to the drug was growing.

24 May 2017

Moderate chocolate intake linked to lower risk of atrial fibrillation

A new study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with researchers at the Harvard T.H. Chan School of Public Health and the Aalborg University and Institute of Cancer Epidemiology in Denmark, found that consuming moderate amounts of chocolate was associated with significantly lower risk of being diagnosed with atrial fibrillation, a common and potentially life threatening type of irregular heartbeat.

24 May 2017

UCLA scientists develop chemical reaction that could yield new fuels and pharmaceuticals

When scientists develop the chemical formulas for new products such as fuels and medications, they often must first create molecules that haven't previously existed.

24 May 2017

Multi-protein biomarker blood test to detect breast cancer can potentially reduce use of biopsy

A new study published in Clinical Breast Cancer demonstrates that Videssa® Breast, a multi-protein biomarker blood test to detect breast cancer, can help inform better decision-making after abnormal mammogram or other breast imaging results and potentially reduce use of biopsy by up to 67 percent.

24 May 2017

Research suggests potential of stem cells to improve tendon healing

New research published online in The FASEB Journal suggests that tendon stem (TSCs) may be able to significantly improve tendon healing by regulating inflammation, which contributes to scar-like tendon healing and chronic matrix degradation.

23 May 2017

Laboratory News and Research

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

New study finds dramatic reorganization of the gut caused by weight loss surgery

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

New NMR machine at TSRI’s Florida campus will help advance drug development process

Gray matter density increases during transition from childhood to young adulthood, study reveals

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

Scientists identify genetic risk factor for equine squamous cell carcinoma

Mettler Toledo GWP verification helps pharmaceutical company decide on weighing equipment

Study finds wearable fitness trackers accurately measure heart rate but not energy expenditure

High quality microplate readers built to last decades by German manufacturer BMG Labtech

Near real-time genomic sequencing reveals how Zika virus entered into the U.S.

Molecule discovered in worm spit could offer solution for non-healing wounds

Yearlong study creates detailed map of microbial colonization in a newly opened hospital

Drug-related cues increase craving, dopamine release in the brain of recreational cocaine users

Isolera™ Dalton 200 intelligent sampling device released by Biotage

New test could help physicians identify appropriate treatment for people with gonorrhea

Moderate chocolate intake linked to lower risk of atrial fibrillation

UCLA scientists develop chemical reaction that could yield new fuels and pharmaceuticals

Multi-protein biomarker blood test to detect breast cancer can potentially reduce use of biopsy

Research suggests potential of stem cells to improve tendon healing

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