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Gedeon Richter and Forest Labs' cariprazine Phase III trials on schizophrenia meet primary endpoint

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive top-line results in 2 Phase III clinical trials of cariprazine (RGH-188) for the treatment of acute exacerbation of schizophrenia.

28 Feb 2012

Examining HIV/AIDS in Zambian prisons

In this post in PSI's "Healthy Living" blog, Mannasseh Phiri, PSI's country representative in Zambia, examines HIV/AIDS in Zambian prisons. Phiri reports the findings of a survey recently conducted by the IN BUT FREE (IBF) Prisons Project "to determine the extent and magnitude of the HIV and AIDS epidemic in Zambia's prisons."

28 Feb 2012

Rapid influenza diagnostic tests highly accurate in children than in adults

A new study conducted by researchers from McGill University, the Research Institute of the McGill University Health Centre (RI MUHC), and Sainte-Justine University Hospital Research Centre, Montreal, has put the accuracy of rapid influenza diagnostic tests (RIDTs) under the microscope.

28 Feb 2012

Actuarial value, health disparities draw attention as part of health law implementation

The Department of Health and Human Services offered a bulletin last week to provide guidance on how insurers should calculate actuarial value. Also, some health policy experts are beginning to question whether the health law's quality provisions might exacerbate the nation's health disparities.

28 Feb 2012

States, governors have different thoughts on insurance exchanges, impact of health law

States are lagging in the creation of health insurance exchanges, the supermarkets where millions of consumers are supposed to buy subsidized private coverage under President Obama's health care overhaul.

28 Feb 2012

Study finds traces of bacteria listeria in ready-to-eat fish products in Vancouver

A University of British Columbia study has found traces of the bacteria listeria in ready-to-eat fish products sold in Metro Vancouver, Canada.

28 Feb 2012

New approaches may increase effectiveness of SCS for severe back pain

New approaches to electrical stimulation—using an implanted device with three columns of electrodes—may increase the effectiveness of spinal cord stimulation (SCS) for severe back pain, suggests a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

28 Feb 2012

Ambient assisted-living technology supports active ageing

'When I am less worried, I do not think about the fact that I'm alone': the words of an older Swedish person who participated in a recent trial of European technology that supports active ageing. Loneliness from being disconnected from friends and family, fears about health and safety and worries about security are some of the many burdens of old age. EU-funded researchers are proving how technology can alleviate the problems.

28 Feb 2012

Childhood adversity may lead to epigenetic changes in glucocorticoid receptor gene

In a look at how major stressors during childhood can change a person's biological risk for psychiatric disorders, researchers at Butler Hospital have discovered a genetic alteration at the root of the association.

28 Feb 2012

The high cost of cancer care

Forty years after the National Cancer Act launched the "war on cancer," the battle is not just finding cures and better treatments but also being able to afford them. New drugs often cost $100,000 or more a year. Patients are being put on them sooner in the course of their illness and for a longer time -; sometimes for the rest of their lives.

28 Feb 2012

NTU's Complexity Programme aims to establish Singapore as Asian hub

Asia will receive a boost in the field of complexity science through a dedicated programme by Nanyang Technological University (NTU).

28 Feb 2012

Older women with recurrent pain more likely to develop depression, obesity

Women age 50 and older who experience worsening pain with aging also have a higher risk for depression, obesity and declining physical function, according to research reported in The Journal of Pain, the peer-review publication of the American Pain Society.

28 Feb 2012

Study finds subtle cognitive deficits in women treated with CMF chemotherapy

Dutch investigators have reported that women who received CMF chemotherapy (a combination regimen including the drugs cyclophosphamide, methotrexate, and 5-fluorouracil) for breast cancer between 1976 and 1995 scored worse on cognitive tests than women who never had cancer.

28 Feb 2012

Vascular Magnetics to advance development of new drug delivery system for PAD

Vascular Magnetics, the first start-up company spun off by The Children's Hospital of Philadelphia, has raised $7 million to advance development of an innovative drug delivery system using magnetically targeted nanoparticles to treat peripheral artery disease.

28 Feb 2012

Aurora-A protein blocks proper functioning of tumor-suppressor p73

A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists reports in the current Cancer Cell.

28 Feb 2012

Diets low in omega-3 fatty acids linked with memory problems

A diet lacking in omega-3 fatty acids, nutrients commonly found in fish, may cause your brain to age faster and lose some of its memory and thinking abilities, according to a study published in the February 28, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2012

UT Southwestern's chairman of pharmacology wins 2012 Rolf Luft Award

Dr. David Mangelsdorf, chairman of pharmacology at UT Southwestern Medical Center, has been awarded the 2012 Rolf Luft Award for research that has advanced understanding of nuclear receptor pathways.

28 Feb 2012

JAM study highlights emerging problem in addiction therapy

A Journal of Addiction Medicine (JAM) study was cited in a recent Center for Substance Abuse Research (CESAR) series highlighting an emerging problem in addiction therapy: the diversion and misuse of the medication buprenorphine.

28 Feb 2012

Research identifies factors in long-term transplant survival

Heart transplant patients who receive new organs before the age of 55 and get them at hospitals that perform at least nine heart transplants a year are significantly more likely than other people to survive at least 10 years after their operations, new Johns Hopkins research suggests.

28 Feb 2012

Biogen Idec, Samsung Biologics establish joint venture to develop and market biosimilars

Samsung Biologics and Biogen Idec announced today that the companies have established their joint venture, Samsung Bioepis Co., Ltd., to develop, manufacture and market biosimilars in keeping with their agreement announced in December.

28 Feb 2012