Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

PhRMA Foundation to focus on value-driven health care in U.S.

The PhRMA Foundation has announced a shift in mission that will focus on building a better system of value assessment in U.S. health care – empowering patients and improving health outcomes and efficiencies – while helping shape a new era of multidisciplinary research and drug development, based strongly in the use of advanced technology and data.

22 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Researchers identify new TB enzyme target to help fight deadly infection

Researchers have found a crucial enzyme in tuberculosis (TB) to target, allowing the development of new treatments to help fight against the disease's drug resistance.

18 Oct 2019

Insilico Medicine presents experimentally validated model for drug discovery at NeurIPS 2019

Insilico Medicine, a biotechnology company developing an end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, is proud to present its paper "A Prior of a Googol Gaussians: a Tensor Ring Induced Prior for Generative Models" at the 33rd Conference on Neural Information Processing Systems (NeurIPS).

16 Oct 2019

New initiative aims to use artificial intelligence to identify early drug candidates

Insilico Medicine, in collaboration with ChemDiv, Inc., launched a drug discovery initiative that aims to use the power of artificial intelligence for screening chemistry space with newly designed compounds.

16 Oct 2019

Widely available drug could reduce deaths in traumatic brain injury patients, major study shows

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study published in The Lancet.

15 Oct 2019

CANDO drug discovery platform focuses on finding new medications for mental illnesses

An estimated 46.6 million U.S. adults struggle with mental illnesses, such as anxiety disorder, according to the National Institute of Mental Health. About half of millennials and 75% of Gen-Zers report having quit jobs for mental health reasons.

15 Oct 2019

How Is Ophthalmology Changing To Meet New Challenges?

Ophthalmology, a highly dynamic space in vision loss and age-related eye diseases with approximately 1.3 billion people living with vision impairment.

From Santen Pharmaceutical Co., Ltd. 15 Oct 2019

Porvair Sciences to showcase new range of microplates at Lab Innovations 2019

Porvair Sciences will showcase its recently extended ranges of ultra-clean deep well and assay microplates for the first time in Europe at the forthcoming Lab Innovations 2019 exhibition.

From Porvair Sciences Limited 14 Oct 2019

Optibrium introduces Augmented Chemistry services to advance drug discovery projects

Optibrium, a developer of software for drug discovery, today announced the introduction of its Augmented Chemistry services, which provide collaborators with novel artificial intelligence technologies to supplement their skills and experience, enabling them to make more effective decisions and advance their drug discovery projects.

From Optibrium Ltd. 10 Oct 2019

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

Insilico Medicine, a company developing an end-to-end drug discovery pipeline utilizing the latest advances in deep learning, has entered into a two-program research collaboration agreement with Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd..

9 Oct 2019

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Thousands of new chemical structures are tested in hopes of discovering a single drug meant to treat a single disease. Of the 5,000 to 10,000 that are prepared, only about 250 of those make it to the pre-clinical stage, and potentially as few as five make it to clinical trials in humans.

8 Oct 2019

Regional chromatography industry meeting in Berlin Zehlendorf was a great success

More than 50 users, technology visionaries and laboratory experts met on Monday, September 30, 2019 for a regional chromatography industry meeting in Berlin Zehlendorf to discuss opportunities and challenges of this analytical laboratory technology.

8 Oct 2019

New protein painting technology could transform drug discovery process

George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind.

8 Oct 2019

New mechanism that controls DNA repair identified

Deoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer.

2 Oct 2019

Using cloning technology to prevent esophageal cancer

Researchers at the University of Houston have replicated the genetic mechanism underlying the transformation of benign esophageal cells into a malignant tumor.

2 Oct 2019

Using AI to transform drug discovery in a big way

According to the National Cancer Institute, approximately 38 percent of men and women will be diagnosed with cancer at some point in their lives.

1 Oct 2019

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

A modern chemotherapy drug is more effective for men with advanced prostate cancer than a second targeted hormone therapy in patients who have stopped responding to treatment, a major clinical trial shows.

30 Sep 2019

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal.

30 Sep 2019

RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

At a time when the previously untapped drug discovery opportunity promised within RNA opens up, the 2nd RNA- Targeted Drug Discovery Summit returns to reunite the leading minds from large pharma, innovative biotech and KOLs of academia to overcome unique discovery and development challenges associated with novel RNA targeted small molecule therapeutics and achieve their seemingly limitless potential.

From RNA-Targeted Drug Discovery Summit 30 Sep 2019

Drug Discovery News and Research

Further Reading

PhRMA Foundation to focus on value-driven health care in U.S.

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

Researchers identify new TB enzyme target to help fight deadly infection

Insilico Medicine presents experimentally validated model for drug discovery at NeurIPS 2019

New initiative aims to use artificial intelligence to identify early drug candidates

Widely available drug could reduce deaths in traumatic brain injury patients, major study shows

CANDO drug discovery platform focuses on finding new medications for mental illnesses

How Is Ophthalmology Changing To Meet New Challenges?

Porvair Sciences to showcase new range of microplates at Lab Innovations 2019

Optibrium introduces Augmented Chemistry services to advance drug discovery projects

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Regional chromatography industry meeting in Berlin Zehlendorf was a great success

New protein painting technology could transform drug discovery process

New mechanism that controls DNA repair identified

Using cloning technology to prevent esophageal cancer

Using AI to transform drug discovery in a big way

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

ELRIG Drug Discovery: Poster Sessions eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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