Laboratory News and Research

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JAX professor receives HFSP grant for 3D genome studies of memory, learning and epilepsy

Jackson Laboratory Professor Yijun Ruan, Ph.D., a leader in the study of the three-dimensional organization of the human genome, has received a three-year grant totaling $1,050,000 from the international Human Frontier Science Program to explore the fundamental mechanics involved in memory and learning as well as epilepsy.

28 Mar 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, will highlight a variety of basic research and population studies at the annual meeting of the American Association for Cancer Research at the Walter E. Washington Convention Center in Washington, D.C., April 1 to 5.

28 Mar 2017

Researchers develop two-pronged approach to personalize breast cancer treatment

The goal of cancer therapy is to destroy the tumor or stop it from growing and spreading to other parts of the body.

28 Mar 2017

New study explores biomechanics of head injury in pediatric patients

The biomechanics of head injury in youths (5 to 18 years of age) have been poorly understood. A new study reported in the Journal of Neurosurgery: Pediatrics set out to determine what biomechanical characteristics predispose youths with concussions to experience transient or persistent postconcussion symptoms.

28 Mar 2017

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists from Tomsk Polytechnic University together with their colleagues from St. Petersburg and London have elaborated a new approach to deliver anti-viral RNAi to target cells against H1N1 influenza virus infection.

28 Mar 2017

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully developed a humanized mouse model showing that so-called NK cells that directly attacking tumors, can survive and maintain function in vivo.

28 Mar 2017

Aircuity helps build energy efficient facilities at Texas Children’s Hospital

Texas Children’s Hospital is an internationally recognized full-care pediatric hospital located in the Texas Medical Center in Houston.

28 Mar 2017

Public-private collaboration to develop more accurate methods of tracking cancer progression

Columbia University Medical Center and NewYork-Presbyterian, in coordination with the Foundation for the National Institutes of Health Biomarkers Consortium, is launching a three-year research collaboration to develop new methods for analyzing digital images that track a patient's response to cancer therapy.

28 Mar 2017

Researchers map key Zika virus protein to accelerate search for cure

A study published today shows how Indiana University scientists are speeding the path to new treatments for the Zika virus, an infectious disease linked to birth defects in infants in South and Central America and the United States.

28 Mar 2017

Research highlights threat of Zika virus to donated blood supplies in the U.S

Investigators have shown that certain screening methods that detect the genetic material of Zika virus can be used to ensure that donated blood supplies remain free of the virus.

28 Mar 2017

Study shows decreasing telomere length may contribute to onset of age-related diseases

Mouse models of human disease have made it possible to gain important insights into many conditions. However, many diseases remain for which no mouse model exists, and large proportion of human diseases without mouse models are associated with aging.

28 Mar 2017

Kent state researchers use DNA origami to create ‘nano cage’ for deeper study of cancer cell growth

According to the American Cancer Society, there will be an estimated 1,688,780 new cancer cases diagnosed and 600,920 cancer deaths in the U.S. in 2017.

28 Mar 2017

Treatment with microRNA re-insulates ravaged nerves, restores limb mobility in mouse models of MS

Scientists partially re-insulated ravaged nerves in mouse models of multiple sclerosis (MS) and restored limb mobility by treating the animals with a small non-coding RNA called a microRNA.

27 Mar 2017

Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

27 Mar 2017

Lund researchers develop porous ‘spaghetti’ to grow cells more naturally

The usual way of cultivating cells is to use a flat laboratory dish of glass. However, inside a human body, the cells do not grow on a flat surface, but rather in three dimensions. This has lead researchers at Lund University in Sweden to develop a porous "spaghetti" of tissue-friendly polymers with cavities in which the cells can develop in a more natural way.

27 Mar 2017

First national survey reveals high burden of iodine deficiency among Israelis

62% of school-age children and 85% of pregnant women in Israel have low iodine intakes, according to the country's first national iodine survey. Government funding and legislation, and a government-regulated program of salt or food iodization, are essential to reducing the deficiency, which poses a high risk of impaired neurological development.

27 Mar 2017

Scientists crack crystal structure of entire ZIKV NS5 protein

Zika virus (ZIKV), which causes Zika virus disease, is spread to people primarily through the bite of an infected Aedes aegypti or Aedes albopictus mosquito. An infected pregnant woman can pass ZIKV to her fetus during pregnancy or around the time of birth. Sex is yet another way for infected persons to transmit ZIKV to others.

27 Mar 2017

Scientists call for better basic-clinical genomic research collaborations

In the era of genome sequencing, it's time to update the old "bench-to-bedside" shorthand for how basic research discoveries inform clinical practice, researchers from The Jackson Laboratory, National Human Genome Research Institute and institutions across the U.S. declare in a Leading Edge commentary in Cell.

27 Mar 2017

Researchers use classroom to understand neurodynamics of real-world social interactions

When going to the movies with a group of friends, one small action can make a big difference when it comes to being on the same page after the movie: eye contact. A simple conversation before the movie sets you up to be more in sync with your friends after the movie.

27 Mar 2017

Laboratory News and Research

JAX professor receives HFSP grant for 3D genome studies of memory, learning and epilepsy

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

Researchers develop two-pronged approach to personalize breast cancer treatment

New study explores biomechanics of head injury in pediatric patients

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists develop humanized mouse model for analyzing functions of NK cells in vivo

Aircuity helps build energy efficient facilities at Texas Children’s Hospital

Public-private collaboration to develop more accurate methods of tracking cancer progression

Researchers map key Zika virus protein to accelerate search for cure

Research highlights threat of Zika virus to donated blood supplies in the U.S

Study shows decreasing telomere length may contribute to onset of age-related diseases

Kent state researchers use DNA origami to create ‘nano cage’ for deeper study of cancer cell growth

Treatment with microRNA re-insulates ravaged nerves, restores limb mobility in mouse models of MS

Study shows how epigenetic randomness helps cancer cells proliferate

Lund researchers develop porous ‘spaghetti’ to grow cells more naturally

First national survey reveals high burden of iodine deficiency among Israelis

Scientists crack crystal structure of entire ZIKV NS5 protein

Scientists call for better basic-clinical genomic research collaborations

Researchers use classroom to understand neurodynamics of real-world social interactions

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