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Study reveals molecular mechanism behind new DOT1L-related disorder

A study from the laboratory of Dr. Hugo J. Bellen, a distinguished service professor at Baylor College of Medicine and a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, has discovered that gain-of-function variants in the DOT1L gene cause a new disorder.

13 Oct 2023

Scientists unravel secrets about the formation of DNA's building blocks

An international team has uncovered details about the formation of DNA's building blocks, paving the way for potential medical and therapeutic applications.

12 Oct 2023

Engineered bacteria deliver synthetic targets to solid tumors

For several years, researchers have been successfully using chimeric antigen receptor (CAR) T cells to target specific antigens found on blood cells as a cure for patients with leukemia and lymphoma.

12 Oct 2023

New study finds host strategy to cope with sleeping sickness

A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology found a new strategy by the host to cope with Trypanosoma brucei infection.

12 Oct 2023

New clinical trial shows simple way to save thousands of units of blood every year

A world-first clinical trial published in JAMA could provide an easy way to save tens of thousands of units of blood every year in Canada and much more worldwide.

12 Oct 2023

Study reassures patients on safety of widely prescribed hypertension drug amlodipine

A new paper in the journal Function, published by Oxford Univetrsity Press, finds that a widely prescribed drug for treating hypertension, amlodipine, is not dangerous for patients, despite recent concerns from researchers and clinicians that taking amlodipine may have risks.

12 Oct 2023

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to four researchers from the Texas Tech University Health Sciences Center (TTUHSC).

12 Oct 2023

Ensuring raw material quality in drug production and manufacturing

In this interview, Thermo Fisher Scientific discusses how to ensure the high quality of raw material in the drug production and manufacturing pipeline.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Oct 2023

Accelerating drug discovery with analytical R&D solutions

In this interview, Thermo Fisher Scientific discusses how to accelerate drug discovery through analytical R&D.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Oct 2023

New drug molecule restores lost nerve-muscle connections, enhances strength

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found.

11 Oct 2023

AI helps neurosurgeons identify brain tumor types on the spot

What type of brain tumor does this patient have? AI technology helps to determine this as early as during surgery, within 1.5 hours. This process normally takes a week.

11 Oct 2023

Advancing neurotoxicity research with INTEGRA pipettes

INTEGRA Biosciences has awarded 31 EVOLVE manual pipettes, GRIPTIPS® pipette tips worth US $1000, and lab accessories to the bioanalytical company DNTOX as part of its recent ‘INTEGRA supports start-ups’ competition, which ran until April 2023.

From INTEGRA Biosciences 10 Oct 2023

New magnetoelectric material bridges gap in severed nerve, restores function

Researchers have long recognized the therapeutic potential of using magnetoelectrics ⎯ materials that can turn magnetic fields into electric fields ⎯ to stimulate neural tissue in a minimally invasive way and help treat neurological disorders or nerve damage.

10 Oct 2023

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Non-melanoma skin cancer (NMSC) is causing a greater number of global deaths than melanoma, the more serious form of skin cancer, a new study presented today at the European Academy of Dermatology and Venerology (EADV) Congress 2023 has found.

10 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

IU Cancer Center awarded grant to train next generation of cancer drug discovery researchers

The Indiana University Melvin and Bren Simon Comprehensive Cancer Center was awarded a prestigious grant to train the next generation of cancer drug discovery and development researchers.

10 Oct 2023

SARS-CoV-2 RNA found in ocular tissues at autopsy, despite minimal inflammation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), infects tissues throughout the human body, including the eye.

10 Oct 2023

Study provides evidence for combination therapy as first-line treatment for relapsed ITP

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, conducted a multicenter comprehensive retrospective analysis to assess the effectiveness and safety of primary single-agent and combination therapies in treating adult patients with relapsed immune thrombocytopenia (ITP).

9 Oct 2023

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

New forum launched to support behavioral research in laboratory animals

COST Action TEATIME have launched a new public forum for those wishing to delve deeper into scientific matters relating behavioral research in laboratory animals.

9 Oct 2023