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Patient adherence an essential factor for successful tuberculosis treatment

Nearly 2 million people die from tuberculosis each year, mainly in the poorest countries. The pathogen, Koch's bacillus, can pass easily by aerial infection from one individual to another. The spread of the disease, favoured by the Aids epidemic and the appearance of multi-resistant strains, has led WHO to make tuberculosis control one of the world's main health priorities.

27 Mar 2007

Cells use 'noise' to make cell-fate decisions

Electrical noise, like the crackle heard on AM radio when lightning strikes nearby, is a nuisance that wreaks havoc on electronic devices. But within cells, a similar kind of biochemical "noise" is beneficial, helping cells transform from one state to another, according to a new study led by a UT Southwestern Medical Center researcher.

25 Mar 2007

Viral protein is an effective preventative against infection

For parents, eight million cases of acute middle-ear infections every year adds up to a lot of sleepless nights and trips to the pediatrician.

25 Mar 2007

AACR's Sixth Annual Landon Awards recognize Richard Kolodner, Douglas Lowy and John Schiller

Scientists whose discoveries have led to fundamental advances in the science and treatment of cancer are the recipients of two prestigious international prizes offered by the Kirk A. and Dorothy P. Landon Foundation and the American Association for Cancer Research.

22 Mar 2007

Trojan horse approach designed to defeats drug-resistant bacteria

A new antimicrobial approach can kill bacteria in laboratory experiments and eliminate life-threatening infections in mice by interfering with a key bacterial nutrient, according to research led by a University of Washington scientist.

19 Mar 2007

FDA clears Xpert EV test for meningitis

The U.S. Food and Drug Administration (FDA) has cleared for marketing a test that uses molecular biology to quickly detect the presence of viral meningitis.

19 Mar 2007

FDA approves Soliris (eculizumab), first treatment for paroxysmal nocturnal hemoglobinuria

The U.S. Food and Drug Administration (FDA) has approved Soliris (eculizumab), the first product for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare type of blood disorder that can lead to disability and premature death.

19 Mar 2007

15,595 meningitis cases this season in Africa

Two months into the dry season in the African "Meningitis Belt", 15,595 cases including 1,670 deaths have been reported to the World Health Organization (WHO) from four countries: Burkina Faso, the Democratic Republic of the Congo, Sudan and Uganda.

19 Mar 2007

Scientists decipher a signaling pathway crucially involved in Crohn's disease and ulcerative colitis

Inflammatory bowel diseases, such as Crohn's disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms.

15 Mar 2007

Aging boosts chances that a family line will be long-lived

Scientists have puzzled over just why organisms evolved aging as a strategy, and now there appears to be an answer. Allowing one individual to carry all the cellular damage inflicted over time, rather than dividing it between two organisms during reproduction, increases the chances that the individual's line will continue to reproduce for many generations to come, a new study indicates.

13 Mar 2007

New method for identifying viruses and bacteria that cause common infections in children

Infectious disease specialists at UT Southwestern Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of the most common acute infections in children.

13 Mar 2007

Antifungal drug kills tuberculosis bug

Scientists hoping to find new treatments for one of the world's most deadly infectious diseases say drugs used to treat common fungal infections may provide the answer.

From The University of Manchester 12 Mar 2007

Quick diagnosis test for streptococcal strains

A streptococcal infection may initially cause nothing more than a relatively harmless sore throat. It can, however, also lead to potentially fatal disease or lifelong disability.

8 Mar 2007

Bold proposal to restructure drug development patents

Weill Cornell Medical College scientist Dr. Carl Nathan has issued a bold call for reforming the pharmaceutical development and patent systems in order to increase the number of vaccines and drugs available to combat neglected diseases that are ravaging the world's poor.

8 Mar 2007

Children under stress develop more fevers

Children whose parents and families are under ongoing stress have more fevers with illness than other children. Published this month in the Archives of Pediatric and Adolescent Medicine, the study also shows the unanticipated conclusion that children's natural killer cell function, part of the body's innate immune system, increases under chronic stress, unlike adults, whose function is decreased.

6 Mar 2007

Clean hands save patient lives

Experts on patient safety are urging countries in Latin America and the Caribbean to join a global effort to improve hand hygiene and related practices in hospitals and health care facilities to help reduce the growing number of deaths and illnesses due to health care-associated infections.

5 Mar 2007

Stress increases acne in teens

The largest study ever conducted on acne and stress reveals that teenagers who were under high levels of stress were 23 percent more likely to have increased acne severity, according to researchers from Wake Forest University School of Medicine and colleagues.

5 Mar 2007