Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

IDT launches high quality, ready-to-use custom oligo pools

Continuing its mission to advance biological research worldwide, Integrated DNA Technologies has launched oPools Oligo Pools – ready-to-use pools of high quality DNA oligonucleotides (oligos) up to 350 nucleotides in length.

From Integrated DNA Technologies 16 Aug 2019

Ziath launches new YouTube channel to share its expertise with laboratories

Ziath is launching a new YouTube channel that will house informative videos previewing the latest innovations in the field of drug discovery and bio-banking sample management for the first time as the company seeks to share its expertise and knowledge with laboratories worldwide.

From Ziath Ltd 16 Aug 2019

Scientists take first step towards digital map of the ion channels in the brain

Researchers have mapped the molecular workings of voltage-gated potassium ion channels within the brain.

16 Aug 2019

Porvair Sciences introduces 5 new deep well microplates

Porvair Sciences has extended its sample storage and collection range with the introduction of 5 new deep well microplates.

From Porvair Sciences Limited 13 Aug 2019

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

UMB startup releases cutting-edge software platform for pharmaceutical researchers

Pumas-AI, a new University of Maryland, Baltimore startup company established by University of Maryland School of Pharmacy faculty members Vijay Ivaturi, PhD, assistant professor, and Joga Gobburu, PhD, MBA, professor, has released its first, cutting-edge software platform for pharmaceutical researchers and clinicians.

9 Aug 2019

New 3D-cardiac tissue platform can predict how heart responds to drugs

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans.

7 Aug 2019

Thermo Fisher Scientific unveils new Krios solution at Microscopy and Microanalysis 2019

Today at Microscopy and Microanalysis 2019, Thermo Fisher Scientific unveiled a new Krios solution designed to break down the barriers to cryo-EM adoption through improved ease-of-use, faster results and the most compact 300kV cryo-EM microscope design on the market.

From Thermo Fisher Scientific – Electron Microscopy Solutions 6 Aug 2019

Sanofi exercises option to advance innovative Bispecific Small Molecule project

Exscientia, the world-leading Artificial Intelligence (AI)-driven drug discovery company, today announced that Sanofi has exercised its option to progress an innovative Bispecific Small molecule project it discovered as part of its new modality collaboration.

From Sanofi 6 Aug 2019

Automating cryo-EM sample preparation

SPT Labtech has today announced the introduction of chameleon, an industry-enabling sample-preparation system for cryo-EM.

From SPT Labtech 6 Aug 2019

Sheffield academic receives funding to protect brain cells affected by Parkinson's

A Sheffield academic has been awarded £100,000 of funding by the Virtual Biotech Programme - the drug development arm of charity Parkinson's UK - to develop a new treatment that could protect brain cells affected by Parkinson's disease, potentially slowing, or stopping its progression for the first time.

6 Aug 2019

New blinking eye-on-a-chip can be used for disease modeling and drug testing

People who spend eight or more hours a day staring at a computer screen may notice their eyes becoming tired or dry, and, if those conditions are severe enough, they may eventually develop dry eye disease.

5 Aug 2019

Scientists use AI to recognize patterns in breast cancer

Scientists have used artificial intelligence to recognize patterns in breast cancer - and uncovered five new types of the disease each matched to different personalized treatments.

2 Aug 2019

Researchers reveal undiscovered hot spots on surface of bacteria's critical enzyme

Researchers reveal previously undiscovered hot spots on the surface of bacteria's critical enzyme, which could guide novel approaches to antibiotic design.

2 Aug 2019

New leukemia treatment developed from common wild flower

Researchers have discovered how to turn a compound from a common wildflower called Feverfew into a new treatment for leukemia.

1 Aug 2019

New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria

Researchers have discovered a weak spot in the cell wall of pathogenic bacteria that could lead to the development of new antibiotics.

1 Aug 2019

NemaMetrix raises $5 million USD funding to expand its Precisome platform

NemaMetrix, an Oregon-based company that provides phenotyping and functional analysis using C. elegans nematodes, today announced it has closed a $5 million USD funding round to expand its Precisome platform: a tool for in vivo testing for early drug discovery, agribio, and precision medicine.

From InVivo Biosystems 30 Jul 2019

Porvair Sciences extends ultra-clean deep well plate range

Porvair Sciences has extended its sample storage and collection range with the introduction of 5 new deep well microplates.

From Porvair Sciences Limited 23 Jul 2019

Researchers develop new compound to block therapeutic target in aggressive blood cancer

Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer.

23 Jul 2019