Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Antioxidant may prevent development of NAFLD in offspring of obese mothers

In new research published online in The FASEB Journal, scientists show that the antioxidant pyrroloquinoline quinone may prevent the development of nonalcoholic fatty liver disease in offspring.

10 Jan 2017

Epigenetic changes favor development of fatty liver in humans and mice

Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver.

9 Jan 2017

Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus.

4 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Einstein awarded more than $160 million NIH grant in federal fiscal year 2016

Investigators at Albert Einstein College of Medicine were awarded more than $160 million from the National Institutes of Health in federal fiscal year 2016.

28 Dec 2016

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

If you're 65 or older and taking more than four medications, resolve to talk to your doctor about doing a New Year's triage to make sure too many pills aren't making you sick, advises Milta Little, D.O., associate professor of geriatrics at Saint Louis University.

26 Dec 2016

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

A study of unprecedented scale has led researchers to identify four previously unknown genetic risk locations for primary sclerosing cholangitis, a liver disease that lacks effective medical therapy.

20 Dec 2016

Mayo Clinic scientists show how hungry liver cells find energy

In a recent Science Advances article, Mayo Clinic researchers show how hungry human liver cells find energy.

20 Dec 2016

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, as well as reduces body fat in an animal model.

16 Dec 2016

UK to officially authorise clinical use of ground-breaking ‘three-person baby IVF’

The United Kingdom will likely this week become the first country to officially authorise clinical use of ground-breaking mitochondrial donation IVF to enable healthy babies to be born to women carrying deadly mitochondrial disease, which starves major organs of energy.

16 Dec 2016

Scientists develop first functional biological pacemaker from human stem cells

Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy.

15 Dec 2016

Revolutionary approach could save lives of sickest patients waiting for liver transplant

There's new hope for patients with liver disease who are waiting for a donor liver to become available for transplantation.

15 Dec 2016

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.

14 Dec 2016

Researchers discover new pathway that opens door to treat non-alcoholic fatty liver disease

Researchers from the University of South Carolina, Duke University, University of Alabama at Birmingham, and Metabolon Inc. Research Triangle Park have discovered a new pathway in the liver that opens the door to treat non-alcoholic fatty liver disease, a condition that affects up to 25 percent of the population and may lead to cirrhosis and eventually liver cancer or failure, and likely other liver diseases.

9 Dec 2016

Oral cavity bacterium linked to development and progression of esophageal cancer

A type of bacterium usually found in the human mouth, Fusobacterium nucleatum, has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan.

9 Dec 2016

Albert Einstein College of Medicine awarded NIH grant to launch diabetes translation research center

The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $2.9-million grant to launch a new center, one of only 8 in the country, for diabetes translation research.

9 Dec 2016

Factors that impact fertility in men

Starting a family can be a stressful process, and there are things that can affect your plans that you may not have considered. According to the Centers for Disease Control and Prevention (CDC), an estimated 18 percent of men who sought help with a fertility specialist were diagnosed with a male-related infertility.

8 Dec 2016

Brain activity of healthy older adults could help predict risk of falling

Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence.

7 Dec 2016

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

A new technique offers better sensitivity and accuracy in detecting an essential biomarker of cancer and inflammatory diseases.

7 Dec 2016

Liver Disease News and Research

Further Reading

Antioxidant may prevent development of NAFLD in offspring of obese mothers

Epigenetic changes favor development of fatty liver in humans and mice

Natural antioxidant can protect offspring of obese mice from NAFLD, study shows

AAV-based gene therapy to treat liver disorders advances into human testing

Einstein awarded more than $160 million NIH grant in federal fiscal year 2016

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

Mayo Clinic scientists show how hungry liver cells find energy

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

UK to officially authorise clinical use of ground-breaking ‘three-person baby IVF’

Scientists develop first functional biological pacemaker from human stem cells

Revolutionary approach could save lives of sickest patients waiting for liver transplant

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Researchers discover new pathway that opens door to treat non-alcoholic fatty liver disease

Oral cavity bacterium linked to development and progression of esophageal cancer

Albert Einstein College of Medicine awarded NIH grant to launch diabetes translation research center

Factors that impact fertility in men

Brain activity of healthy older adults could help predict risk of falling

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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