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Using hearts from hepatitis C-positive donors presents an opportunity to expand donor pool

Patients who were transplanted with hearts from hepatitis C-positive donors had comparable outcomes after one year to patients who received hearts from donors that didn't have the disease, according to a Vanderbilt University Medical Center study published in JAMA Cardiology.

22 Dec 2019

UTHealth scientist receives NIH grants for liver injury research

Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston.

21 Dec 2019

Triple transplant patients encourage people to register as organ and tissue donors

Four University of Chicago Medicine patients who received rare triple-organ transplants came together publicly for the first time to encourage people to register as organ and tissue donors, hoping to raise awareness about giving the gift of life during a holiday season focused on giving.

20 Dec 2019

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

The number of people who need renal replacement therapy is increasing

The ERA-EDTA Registry collects data on renal replacement therapy from the national and regional renal registries in Europe and from countries bordering the Mediterranean. For the 2017 Annual Report, data sets from 53 national or regional renal registries in 37 countries were compiled. A total population of 694,024,000 people was analyzed.

19 Dec 2019

Routine cardiac stress test turns into lifesaving gift

Erika Hosey, a cardiovascular technician at University Hospitals Ahuja Medical Center, ended the year by giving a life-changing gift to a patient in need. While performing a routine cardiac stress test, she drummed up a conversation. She learned that her patient, Denise Butvin, had kidney disease and needed transplant surgery.

19 Dec 2019

Science has not been able to create a substitute for human blood

Science has been able to create and employ a number of medical marvels, such as the artificial heart and synthetic insulin. But not a substitute for human blood.

19 Dec 2019

Scientists evaluate HIV/AIDS, diabetes and organ transplant drugs as possible therapies for Alzheimer's

More than ever before, Alzheimer's researchers understand that a variety of approaches will be needed - most likely used in combination - for effective treatment of the disease.

18 Dec 2019

Brazilian researchers create hepatic organoids by 3D bioprinting

Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.

17 Dec 2019

Researchers identify protein that is key for successful viral DNA uncoating

Viruses have been part of animals and humans for eons. When viruses invade a cell, they can infiltrate the nucleus with their genome and become part of the genome of the infected organism. Viruses transfer their genes between various organisms, as well as between tissues containing well differentiated cells inside a living creature. But how they uncoat their well-packed genes and release them to cause infection is largely unknown.

17 Dec 2019

Stroke drug improves stem cell therapy in rat spinal cord injury models

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations.

17 Dec 2019

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.

11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Transplant patient finds out his DNA has been replaced by that of his donor

A bone marrow transplant recipient later found out that the DNA in his blood and semen had been replaced by that of his donor.

10 Dec 2019

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia that has relapsed.

10 Dec 2019

In campaign to stop teen vaping, states turn to tried-and-true remedy: taxes

Kathleen Hambleton once used to spend $100 a week on Marlboro Reds.

10 Dec 2019

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations.

9 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma, easing concerns that these patients are at heightened risk for severe immune-related complications.

9 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

Transplant News and Research

Using hearts from hepatitis C-positive donors presents an opportunity to expand donor pool

UTHealth scientist receives NIH grants for liver injury research

Triple transplant patients encourage people to register as organ and tissue donors

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

The number of people who need renal replacement therapy is increasing

Routine cardiac stress test turns into lifesaving gift

Science has not been able to create a substitute for human blood

Scientists evaluate HIV/AIDS, diabetes and organ transplant drugs as possible therapies for Alzheimer's

Brazilian researchers create hepatic organoids by 3D bioprinting

Researchers identify protein that is key for successful viral DNA uncoating

Stroke drug improves stem cell therapy in rat spinal cord injury models

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Transplant patient finds out his DNA has been replaced by that of his donor

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

In campaign to stop teen vaping, states turn to tried-and-true remedy: taxes

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

Important biomarker may help in determining prognosis of brain cancer patients

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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