Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Scientists identify new way to target bottleneck for cancer cell growth

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.

23 Jul 2019

Researchers publish review on serial femtosecond crystallography

Researchers from the Moscow Institute of Physics and Technology have published a review on serial femtosecond crystallography, one of the most promising methods for analyzing the tertiary structure of proteins.

22 Jul 2019

Eisai presents new research evaluating correlation of Abeta in plasma and CSF with automated protein assay system

Eisai Co.,Ltd. announced its latest research on evaluation about correlation of amyloid beta (Abeta) in plasma and in cerebrospinal fluid (CSF) by high precision measurement with the newly developed automated protein assay system, jointly developed with Sysmex Corporation, using full automated immunoassay system HISCLTM series for creating the simplified diagnosis of Alzheimer's disease with blood was presented at the Alzheimer's Association International Conference held in Los Angeles, California, United States, from July 14 to 18, 2019.

From Eisai 19 Jul 2019

IT Faces the Digital Pathology Data Tsunami

Digital pathology is the viewing, analyzing, and managing of digitalized pathology slides with computer technology.

From Huron Digital Pathology 17 Jul 2019

Researchers open the door to a new era of medicinal chemistry

Progress in the pharmaceutical industry depends largely on the achievements and advances in medicinal chemistry.

14 Jul 2019

Olympus Europe and Cytosurge join hands to accelerate drug development, single cell research

Olympus Europe and Cytosurge have partnered in order to accelerate common innovation of next-generation tools for single cell experiments and to expand the distribution of the versatile FluidFM BOT single cell research tool.

From Evident Corporation - Life Sciences 10 Jul 2019

Researchers develop new technique to enhance infection-fighting potential of natural chemicals

Researchers in Japan have identified multiple promising new drug candidates to treat antibiotic-resistant infections, including the superbug MRSA (methicillin-resistant Staphylococcus aureus).

8 Jul 2019

New alliance will focus on the structural visualization of novel druggable sites

PhoreMost has entered into an alliance with CCBT in India for the structural visualization of novel druggable sites across multiple targets.

From PhoreMost 8 Jul 2019

Computer-generated flu vaccine enters clinical trials in the US

A seasonal flu vaccine that has been developed entirely by artificial intelligence on a computer is set to be tested in clinical trials in the US.

4 Jul 2019

Advances in artificial intelligence could shed light on aging process

There are two kinds of age: chronological age, w hich is the number of years one has lived, and biological age, which is influenced by our genes, lifestyle, behavior, the environment and other factors.

4 Jul 2019

Hesperos' multi-organ model correctly determine cardiotoxic mechanisms

Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo.

4 Jul 2019

Dundee and Bukwang Pharm announce partnership to develop new drug for Parkinson's

The University of Dundee's Drug Discovery Unit has announced a multi-million-pound partnership with Korea-based Bukwang Pharmaceutical Company in a bid to develop a new drug treatment for Parkinson's disease.

3 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

3D breast tumor models may improve drug discovery and testing

Dr. Hossein Tavana, an associate professor of biomedical engineering at The University of Akron, has received a grant of $1.13 million from the prestigious National Cancer Institute to further develop 3D tumor models of triple-negative breast cancer -- which may improve drug testing and lead to the discovery of new, more effective anticancer drugs.

2 Jul 2019