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$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies, a study led by Dana-Farber Cancer Institute researchers suggests.

8 Dec 2019

Genetic features of AML in older patients can predict outcomes after stem cell transplant

For older patients with acute myeloid leukemia, the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the 61st American Society of Hematology (ASH) Annual Meeting.

8 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

Pilot clinical trial tests new treatment for type 1 diabetes

Type 1 diabetes is a chronic condition in which the body's own immune system attacks and destroys beta cells in the pancreas. Once the beta cells are destroyed, the pancreas can no longer produce insulin. Currently, there is no cure for T1D and treatment focuses on managing blood sugar levels.

6 Dec 2019

Preoperative rehabilitation program for older adults leads to better outcomes

Older adults who "train" for a major operation by exercising, eating a healthy diet, and practicing stress reduction techniques preoperatively have shorter hospital stays and are more likely to return to their own homes afterward rather than another facility, compared with similar patients who do not participate in preoperative rehabilitation, according to research findings.

5 Dec 2019

$Nerve signaling pathway crucial to healing fractures, study shows$

Nerve signaling pathway crucial to healing fractures, study shows

Sticks and stones may break one's bones, but healing them requires the production of a protein signal that stimulates the generation, growth and spread of vital nerve cells, or neurons, throughout the injured area.

5 Dec 2019

No differences found in survival, acute rejection in patients receiving lungs from increased-risk donors

Cleveland Clinic researchers have found that using lungs from donors who are considered high risk for certain infectious diseases compared to standard risk donors results in similar one-year survival for recipients. In addition, researchers saw no difference in rejection or graft (donor lung) survival after one year in patients receiving lungs from increased-risk donors.

5 Dec 2019

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

Investigators in the Blood and Marrow Transplant Program at Rutgers Cancer Institute of New Jersey compared outcomes for patients having undergone allogeneic stem cell transplant when post-transplant cyclophosphamide (PCy, a type of chemotherapy) was added as part of standard treatment to prevent disease through an immune response (immunoprophylaxis) than if this standard treatment was given alone.

5 Dec 2019

New dialysis approach provides high levels of satisfaction for kidney patients

A new study reports high levels of patient satisfaction with a minimally invasive approach to creating vascular access for kidney patients who require hemodialysis.

5 Dec 2019

California surprise-billing law protects patients but aggravates many doctors

More than two years after California's surprise-billing law took effect, there's one thing on which consumer advocates, doctors and insurers all agree: The law has been effective at protecting many people from bills they might have been saddled with from doctors who aren't in their insurance network.

5 Dec 2019

New program receives national recognition for treating hypertrophic cardiomyopathy

When Kayla Green was first diagnosed with hypertrophic cardiomyopathy, she felt vindicated.

4 Dec 2019

A major step toward preventing GvHD in patients receiving bone marrow transplants

A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use.

4 Dec 2019

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Jacob Scott, M.D., Ph.D., a physician researcher from Cleveland Clinic's Department of Translational Hematology and Oncology Research, recently received a $2.8 million grant from the National Cancer Institute, part of the National Institutes of Health, to study how ecological and evolutionary mechanisms contribute to lung cancer development and progression, and how the interplay between these mechanisms may provide novel treatment insights.

4 Dec 2019

Study highlights the need to adhere to more uniform diagnostic criteria for rare lymphoma

In what is believed to be one of the largest studies of a rare disorder known as primary cutaneous gamma delta T-cell lymphoma, Rutgers Cancer Institute of New Jersey investigators and other collaborators examined characteristics, treatment patterns and outcomes of the disease, and determined accurate diagnosis of the disease requires ongoing analysis.

4 Dec 2019

Transplant News and Research

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

Genetic features of AML in older patients can predict outcomes after stem cell transplant

New startup aims to prevent reperfusion-related organ damage after liver transplant

Pilot clinical trial tests new treatment for type 1 diabetes

Preoperative rehabilitation program for older adults leads to better outcomes

Nerve signaling pathway crucial to healing fractures, study shows

No differences found in survival, acute rejection in patients receiving lungs from increased-risk donors

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

New dialysis approach provides high levels of satisfaction for kidney patients

California surprise-billing law protects patients but aggravates many doctors

New program receives national recognition for treating hypertrophic cardiomyopathy

A major step toward preventing GvHD in patients receiving bone marrow transplants

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Study highlights the need to adhere to more uniform diagnostic criteria for rare lymphoma

Healthcare heroes can come from unexpected places

Transplant patients diagnosed with prostate cancer may not need to delay transplantation

UIC researchers receive $2.9 million to study sleep apnea and chronic kidney disease

New treatment approach could improve outcomes for people with cystic fibrosis

Doctors bring dead donor heart back to life in US first

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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