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The glow points the way: coupled enzyme test helps in the search for the right biocatalyst

The chemical industry is going biological: the use of biocatalysts, called enzymes, allows many products to be prepared very efficiently, economically, and in an environmentally safe manner.

From The University of Manchester 14 Dec 2005

Chlamydia loves lipid droplets

Invasive bacterial pathogens, the Chlamydiae know us very, very well. The Chlamydiae learned to parasitize eukaryotic cells half a billion years ago by reprogramming cellular functions from within.

13 Dec 2005

Streptococcus mutans copes without pathway

Leave it to the bacteria that cause tooth decay to be able to live without something all cells were thought to require.

13 Dec 2005

A colonization factor links Vibrio cholerae environmental survival and human infection

Opening a new door to an effective vaccine and therapy for a disease that strikes thousands annually, researchers at Dartmouth Medical School discovered that the bacteria that causes the intestinal disease Cholera spreads in the environment in much the same way it infects humans.

13 Dec 2005

Antibacterial coatings on hip and knee implants cut infection rates

Putting antibacterial coatings on hip and knee implants and biomedical devices such as catheters could cut infection rates following surgery and significantly reduce health care costs and improve quality of life for patients, researchers at the University of South Australia have found.

13 Dec 2005

Finding how water channels - aquaporins - open and close may lead to new drugs

Living organisms are dependent on being able to adjust the water content in their cells. This is achieved by regulating the flow of water through the cell membrane.

12 Dec 2005

Hospital "super super bug" stronger than MRSA

According to reports eleven patients at a British hospital have acquired a superbug said to be stronger than MRSA.

11 Dec 2005

New type of sulfite reductase

Biswarup Mukhopadhyay and Eric Johnson from the Virginia Bioinformatics Institute at Virginia Tech have discovered a novel enzyme that represents an ancient detoxification system and provides a clue to the development of early metabolism on earth.

7 Dec 2005

Garvan scientists explain stress and sickness

Garvan Institute scientists have discovered how a hormone, known as neuropeptide Y (NPY), can prevent our immune system functioning properly, paving the way for two new major opportunities for therapeutic intervention.

7 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Bacterial DNA and IVF contamination risk on New Scientist

Some children conceived by a common method of IVF could be carrying chunks of bacterial DNA in their chromosomes, according to a study in mice. The researchers who conducted the work say that such accidental genetic modification would be very rare, but they argue that fertility doctors should take more precautions to exclude it.

30 Nov 2005

Cranberry flavoured toothpaste may help stop decay

According to researchers cranberries, well-known for their ability to help thwart urinary tract infections, may also help prevent tooth decay and cavities.

28 Nov 2005

Cranberry juice protects teeth against cavities

Families gathered around the Thanksgiving dinner table might consider giving thanks for the bacteria-busting ability of cranberry juice, say dental researchers who have discovered that the beverage holds important clues for preventing cavities.

26 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence

By using pathogenic fungi as model systems for understanding fungal diseases, two groups of researchers are reporting new work that offers insight into how carbon dioxide (CO2) governs the morphogenic changes that allow pathogenic fungi to survive in different environments and invade the human body

21 Nov 2005

Study of how bacteria change their metabolic networks

Bacteria feel pressures to evolve antibiotic resistance and other new abilities in response to a changing environment, and they react by 'stealing' genetic information from other better-adapted types of bacteria, according to research published in Nature Genetics.

20 Nov 2005

Study reveals how T cells analyze and react to the signals of infection at the immunological synapse

The immune system is highly complex. The cast of characters alone required to marshal an immune response to a foreign invader can number in the millions as the body's soldiers, T cells, are called into action.

20 Nov 2005

Six gene variants predict heart muscle damage after cardiac surgery

Duke University Medical Center researchers have found that patients with six specific variants of genes involved in the body's immune response are significantly more likely to suffer damage of heart tissue after cardiac surgery.

16 Nov 2005