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Study shows that PCCs can reverse blood thinning effects of XARELTO in healthy subjects

Janssen Research & Development, LLC announced today results of an open label, single-center, parallel group study showing that a type of medication called prothrombin complex concentrates can reverse the blood thinning effects of XARELTO (rivaroxaban) in healthy subjects.

2 Jul 2013

Tel-Aviv research shows physicians delay diagnosis of cervical spondylotic myelopathy

Researchers from The Tel-Aviv Medical Center found delays in diagnosis of cervical spondylotic myelopathy (CSM) averaging 2 years in 42 patients who eventually underwent surgery. This is an important finding, because previous studies have shown that early diagnosis and treatment of CSM lead to better outcomes.

2 Jul 2013

Janssen receives complete response letter from FDA for XARELTO sNDA

Janssen Research & Development, LLC today announced the U.S. Food and Drug Administration has issued a complete response letter for the supplemental New Drug Application for XARELTO (rivaroxaban) to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

28 Jun 2013

UH Eye Institute to use Argus II Retinal Prosthesis System to treat patients with RP

University Hospitals Eye Institute will be one of the first medical centers in the United States to offer the Argus II Retinal Prosthesis System.

28 Jun 2013

Orthopedic care: an interview with Dereesa Purtell Reid, CEO of Hoag Orthopedic Institute

Similar to other surgical procedures, orthopaedic surgery continues to progress toward more minimally invasive surgical techniques, with shorter inpatient length of stays and new opportunities for some procedures to shift to the outpatient care setting.

27 Jun 2013

Researchers study possible alternative medications to treat cancer-related pain

Researchers at the Brain and Spine Institute at John Theurer Cancer Center at HackensackUMC, one of the nation's 50 best hospitals for cancer, are studying a possible alternative to side effect-ridden opioid-based medications to treat cancer-related pain.

27 Jun 2013

Researchers use neuroimaging abnormalities to detect timing of abusive head trauma in infants

Researchers at Penn State College of Medicine and Penn State Milton S. Hershey Medical Center (Hershey, Pennsylvania) have categorized the appearance and evolution of abnormalities on neuroimages that represent abusive head trauma (AHT) in infants.

26 Jun 2013

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Investigators from the Centers for Disease Control and Prevention describe pathologic findings from 40 case reports of fungal infection in patients who had been given contaminated epidural, paraspinal, or intra-articular (into joints) steroid injections and correlate these findings with clinical and laboratory data.

26 Jun 2013

Caspase-2 protein contributes to cognitive decline associated with Alzheimer's disease

Researchers at Columbia University Medical Center have demonstrated that a protein called caspase-2 is a key regulator of a signaling pathway that leads to cognitive decline in Alzheimer's disease.

26 Jun 2013

Researchers examine effect of ADHD in children recovering from mild traumatic brain injury

Researchers at Children's Hospital of Pittsburgh, the University of Pittsburgh, and the University of Chicago have found that children with attention deficit hyperactivity disorder are more likely to demonstrate a moderate disability after sustaining a mild traumatic brain injury than children without ADHD.

26 Jun 2013

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient's own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

20 Jun 2013

Smoking before surgery can lead to morbidity and complications for neurosurgical procedures

The effects of long-term cigarette smoking on morbidity and mortality have long been known. In a more immediate sense, smoking in the days and weeks before surgery can lead to morbidity and complications for many surgical procedures.

19 Jun 2013

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.

19 Jun 2013

MRI screening of aortic atherosclerosis can predict risk of heart attacks and other CVDs

Magnetic resonance imaging (MRI) of aortic atherosclerosis can predict the risk of heart attacks and other cardiovascular events in otherwise healthy individuals, researchers at UT Southwestern Medical Center have found.

19 Jun 2013

UHCMC physicians design new procedure to clear blocked carotid arteries, prevent stroke

Physicians at University Hospitals Case Medical Center enrolled their first patients in the ROADSTER Study, a global, multicenter clinical trial evaluating a novel, less-invasive procedure to help clear blockages in carotid arteries and prevent strokes.

19 Jun 2013

Professor Moshe Shoham recognized with Thomas A. Edison Patent Award

Mazor Robotics Ltd., a developer of innovative surgical robots and complementary products, today announced that Professor Moshe Shoham was awarded the Thomas A. Edison Patent Award from the American Society of Mechanical Engineers.

18 Jun 2013

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

A treatment known as whole body vibration therapy significantly increases bone strength among adolescents with cerebral palsy, a new clinical trial from New Zealand shows. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Two MRI measurements of abdominal aorta associated with future cardiovascular events

In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta - the amount of plaque in the vessel and the thickness of its wall - are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

18 Jun 2013

Celgene International Sàr presents PALACE 3 phase III results of apremilast in psoriatic arthritis at EULAR

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ: CELG), today announced results from PALACE 3, the Company's third phase III study in psoriatic arthritis (PsA), at EULAR, the European Congress of Rheumatology annual meeting in Madrid, Spain.

15 Jun 2013

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

Stem cells have long been touted as the next big thing. Well just maybe, it is here. According to Dr. Dennis Lox, some patients with a disorder of the bone called avascular necrosis (AVN), have turned to stem cell therapy for aid.

15 Jun 2013

Spine News and Research

Study shows that PCCs can reverse blood thinning effects of XARELTO in healthy subjects

Tel-Aviv research shows physicians delay diagnosis of cervical spondylotic myelopathy

Janssen receives complete response letter from FDA for XARELTO sNDA

UH Eye Institute to use Argus II Retinal Prosthesis System to treat patients with RP

Orthopedic care: an interview with Dereesa Purtell Reid, CEO of Hoag Orthopedic Institute

Researchers study possible alternative medications to treat cancer-related pain

Researchers use neuroimaging abnormalities to detect timing of abusive head trauma in infants

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Caspase-2 protein contributes to cognitive decline associated with Alzheimer's disease

Researchers examine effect of ADHD in children recovering from mild traumatic brain injury

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

Smoking before surgery can lead to morbidity and complications for neurosurgical procedures

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

MRI screening of aortic atherosclerosis can predict risk of heart attacks and other CVDs

UHCMC physicians design new procedure to clear blocked carotid arteries, prevent stroke

Professor Moshe Shoham recognized with Thomas A. Edison Patent Award

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

Two MRI measurements of abdominal aorta associated with future cardiovascular events

Celgene International Sàr presents PALACE 3 phase III results of apremilast in psoriatic arthritis at EULAR

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

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Automating research - solutions and best practices

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