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Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Building on earlier clinical trials, UCLA researchers have confirmed that the "breakthrough" drug palbociclib when used in combination with the traditional hormonal therapy letrozole delays progression of advanced breast cancer significantly and without the harsh side effects seen in some women prescribed letrozole alone.

18 Nov 2016

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

When HIV attacks a T cell, it attaches itself to the cell's surface and launches a "harpoon" to create an opening to enter and infect the cells.

18 Nov 2016

Male brains appear to consume more energy than women when multitasking

It has long been known to science that women find it easier than men to multitask and switch between tasks.

17 Nov 2016

New microscopy technique grabs images faster than typical lab cameras

A new Rice University technique grabs images of chemical processes that happen faster than most laboratory cameras are able to capture them.

17 Nov 2016

Scientists map reorganization of genetic material in cells using 3-D imaging technique

Scientists have mapped the reorganization of genetic material that takes place when a stem cell matures into a nerve cell.

17 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

The virus that causes hepatitis C protects itself by blocking signals that call up immune defenses in liver cells, according to University of Washington researchers and colleagues reporting Nov. 14 in Nature Medicine.

17 Nov 2016

Supercomputer models play key role in finding new drug candidates to combat antibiotic resistance

Supercomputer simulations at the Department of Energy's Oak Ridge National Laboratory have played a key role in discovering a new class of drug candidates that hold promise to combat antibiotic resistance.

17 Nov 2016

New mouse model by FDA's scientists provides platform for improving understanding of Zika virus pathology

A new mouse model developed by scientists at the U.S. Food and Drug Administration may help in exploring the potential activity of Zika virus vaccines and therapeutics.

17 Nov 2016

Novel technology could speed up diagnosis and improve monitoring of COPD

This technology is now being taken forward commercially through the recently formed spin-out company PulmonIR Ltd.

17 Nov 2016

Exposure to allergens during pregnancy alters the brain makeup of fetuses and newborn rats

A new study in rats could begin to explain why allergies during pregnancy are linked to higher risks for attention-deficit hyperactivity disorder and autism in children.

17 Nov 2016

Exposure to e-cigarette vapor destroys large number of mouth cells

A large number of mouth cells exposed to e-cigarette vapor in the laboratory die within a few days, according to a study conducted by Université Laval researchers and published in the latest issue of Journal of Cellular Physiology.

16 Nov 2016

Suppressed vaginal immune response makes women more susceptible to RNA viruses

Scientists at the Gladstone Institutes discovered that the vaginal immune system is suppressed in response to RNA viruses, such as Zika.

16 Nov 2016

High-fat diet may have negative impact on maturation of the brain

Junk food is a burgeoning problem for modern society: we literally have too much on our plate. Fatty and unhealthy foods are especially popular with young children and adolescents. They are often the cheapest and most convenient eating option.

16 Nov 2016

Food restriction may be potential treatment strategy for certain types of cancers, research suggests

Could limiting food intake be a valid treatment strategy for certain types of cancers? New research in The FASEB Journal suggests "maybe."

16 Nov 2016

How toxic is your stress?

The term “stress” originates not in our minds or bodies, but from physics. It is the internal forces generated in an object in response to an external load. In the 1950s, Hans Selye adopted the term to characterize how living organisms change...

16 Nov 2016

FDA approves new assay for diagnosis of IBD

Inova Diagnostics, a worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, is pleased to announce the US Food and Drug Administration clearance of QUANTA Lite Calprotectin Extended Range, an assay which aids in the diagnosis of Inflammatory Bowel Disease (IBD), and can help differentiate IBD from Irritable Bowel Syndrome (IBS).

16 Nov 2016

Phage therapy may be solution to treating antibiotic-resistant bacterial infections

Phage therapy may be a solution to treating infections caused by antibiotic-resistant bacteria. Since 2013, researchers at the University of Helsinki in Finland have collected bacteriophages to combat antibiotic-resistant bacterial strains, and hope to start clinical phage therapy trials in the near future.

16 Nov 2016

Study: Fungal asthma in UK greatly exceeds prior estimates

Experts are warning of a significant increase in the number of people in the UK who are living with invasive and serious fungal diseases that affect the lungs, bloodstream and brain and can sometimes lead to death.

16 Nov 2016

Scientists develop wearable terahertz scanner for noninvasive inspections of medical, drug delivery equipment

Scientists at Tokyo Institute of Technology have developed a portable and wearable terahertz scanning device made using arrays of carbon nanotubes, for non-invasive inspection of three-dimensional objects without requiring bulky peripheral optical components.

16 Nov 2016

Laboratory News and Research

Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

Male brains appear to consume more energy than women when multitasking

New microscopy technique grabs images faster than typical lab cameras

Scientists map reorganization of genetic material in cells using 3-D imaging technique

BAG3 protein plays protective role by limiting reperfusion injury to the heart

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

Supercomputer models play key role in finding new drug candidates to combat antibiotic resistance

New mouse model by FDA's scientists provides platform for improving understanding of Zika virus pathology

Novel technology could speed up diagnosis and improve monitoring of COPD

Exposure to allergens during pregnancy alters the brain makeup of fetuses and newborn rats

Exposure to e-cigarette vapor destroys large number of mouth cells

Suppressed vaginal immune response makes women more susceptible to RNA viruses

High-fat diet may have negative impact on maturation of the brain

Food restriction may be potential treatment strategy for certain types of cancers, research suggests

How toxic is your stress?

FDA approves new assay for diagnosis of IBD

Phage therapy may be solution to treating antibiotic-resistant bacterial infections

Study: Fungal asthma in UK greatly exceeds prior estimates

Scientists develop wearable terahertz scanner for noninvasive inspections of medical, drug delivery equipment

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