Metabolome News and Research

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Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

6 Sep 2018

Investigators identify group of blood metabolites that could help detect autism

Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder

6 Sep 2018

Researchers make discovery about yeast metabolism that could help drug developers

Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

6 Sep 2018

Study yields new insights into why the system needs sleep

Sleep is essential for brain functionality and overall health but understanding how sleep delivers its beneficial effects remains largely unknown. In an article publishing on August 9 in the open access journal PLOS Biology, Shanaz Diessler and Maxime Jan at the University of Lausanne and the SIB Swiss Institute of Bioinformatics (Switzerland), sleep researchers are exploring new and unbiased approaches that can take sleep to a systems level.

10 Aug 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

New computational method identifies molecular signatures that distinguish individuals

EMBL researchers have designed a computational method to jointly analyze multiple types of molecular data from patients in order to identify molecular signatures that distinguish individuals.

21 Jun 2018

Rural and urban microbiota differ from a young age, finds new study

A new study has shown that differences in the human gut microbiome between people living in rural versus urban areas of Nigeria begin at a very young age.

7 Jun 2018

Breakthrough research could pave way for personalized obesity treatments

Research by scientists at King's College London into the role the gut plays in processing and distributing fat could pave the way for the development of personalized treatments for obesity and other chronic diseases within the next decade.

28 May 2018

UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping "'omics" data onto whole organs.

20 Oct 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

Researchers highlight role of micro-guests in pathologic processes

We host more microbiota than our own cells. These micro-guests produce metabolites that are only beginning to be appreciated as important factors in pathologic processes, from chronic inflammatory diseases to preterm birth.

1 Aug 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

New study finds dramatic reorganization of the gut caused by weight loss surgery

Obesity, already a global epidemic, is on the rise. Over one-third of the U.S. population is currently afflicted, according to the Centers for Disease Control and the monetary costs alone are approaching $150 billion dollars annually.

26 May 2017

Decoding the Exposome Through Breath Biomarkers

The human exposome is probably best defined as “everything that is not the genome.” This is a bit tongue in cheek, but basically, the exposome is comprised of all of the chemicals in your body from the environment, food, consumer products, their metabolites, the endogenous “housekeeping” chemicals, the cellular wastes from energy production, as well as all of the messenger compounds and life supporting chemicals.

From Pittcon 24 Feb 2017

NMR and metabolic phenotyping

In this interview, Dr Harmut Schafer introduces the work being done at the Phenome Center in Birmingham, on metabolic phenotyping using NMR.

From Bruker BioSpin - NMR, EPR and Imaging 31 Jan 2017

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages.

From Bruker BioSpin - NMR, EPR and Imaging 17 Jan 2017

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota (bacteria in the uterine cavity) play an important role in determining whether women are able to get pregnant via in vitro fertilization (IVF), according to a new study published in the American Journal of Obstetrics and Gynecology.

6 Dec 2016

New Baylor study aims to investigate antibiotic effect in children with ASD

Over the Thanksgiving holiday in 2012, John Rodakis, a father of a child with autism, observed his son's condition dramatically improve while taking a common antibiotic.

1 Dec 2016

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Scientists from Tohoku University's Tohoku Medical Megabank Organization have published research about genetic diversity and metabolome in Scientific Reports.

1 Sep 2016

UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States.

31 Aug 2016

Metabolome News and Research

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Investigators identify group of blood metabolites that could help detect autism

Researchers make discovery about yeast metabolism that could help drug developers

Study yields new insights into why the system needs sleep

Study identifies constellation of metabolites linked to ME/CFS

New computational method identifies molecular signatures that distinguish individuals

Rural and urban microbiota differ from a young age, finds new study

Breakthrough research could pave way for personalized obesity treatments

UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

Analytical Science in Precision Medicine

Researchers highlight role of micro-guests in pathologic processes

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

New study finds dramatic reorganization of the gut caused by weight loss surgery

Decoding the Exposome Through Breath Biomarkers

NMR and metabolic phenotyping

Metabolomics and NMR

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

New Baylor study aims to investigate antibiotic effect in children with ASD

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

UTHealth scientists discover powerful predictors of congestive heart failure

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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