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Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, asthma, cancer, diabetes, heart disease and even mental illness.

24 Oct 2016

TSRI scientists discover reason for lack of successful HCV vaccine design

Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute have discovered one reason why success has so far been elusive.

24 Oct 2016

Novel approach could help counter Influenza A virus in immune-compromised patients

To infect its victims, influenza A heads for the lungs, where it latches onto sialic acid on the surface of cells.

24 Oct 2016

Adult brain cells may be vulnerable to Zika infection, new study suggests

Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.

24 Oct 2016

Choline deficiency in sows during pregnancy impacts nutrient composition of milk

Choline is an essential nutrient that is used by the body in a number of ways. However, nearly 90 percent of adults do not get the recommended amount in their diets.

24 Oct 2016

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells.

24 Oct 2016

Researchers identify negative role of oxidation in new blood cells

Oxygen in the air is well known to cause damaging rust on cars through a process known as oxidation.

24 Oct 2016

Danish researchers develop new method to study distribution of tracer in tumours

A Danish research team is behind a new method for studying how a tracer is distributed in a cancer tumour via its extensive vascular network.

24 Oct 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

Myriad Genetics and ION Solutions partner to provide accurate, comprehensive hereditary cancer tests

Myriad Genetics, Inc., a global leader in personalized medicine, and ION Solutions, a part of AmerisourceBergen, and the largest physician services organization specializing in the support of community oncology, announced today that they have entered into a relationship to deliver quality hereditary cancer test results and services to ION member practices.

24 Oct 2016

Systec to showcase comprehensive range of autoclaves at MEDICA 2016

Once again, Systec GmbH, the leading manufacturer of autoclaves, including laboratory autoclaves, media preparators, and plate pourers for liquid media and microbiological culture media, will be presenting the highlights of its comprehensive product range at this year’s Medica.

24 Oct 2016

FDA approves new fully automated blood analyzer for high-volume transfusion labs

Ortho Clinical Diagnostics, a global leader of in vitro diagnostics, today announced that ORTHO VISION Max, a fully automated blood analyzer for high-volume transfusion medicine laboratories, received 510(k) clearance, signifying its conformity with U.S. Food and Drug Administration regulation.

24 Oct 2016

PSH model of care provides better outcomes and decreases length of hospital stay

Decreasing the number of tests, blood transfusions and length of time in the hospital, while improving patients' pain management and communication with physicians were the results of implementing the Perioperative Surgical Home (PSH) model of care at TEAMHealth Anesthesia at Tampa General Hospital in Tampa, Fla., according to a study presented at the ANESTHESIOLOGY® 2016 annual meeting.

24 Oct 2016

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Researchers at the Medical University of South Carolina Hollings Cancer Center have discovered a mechanism that confers resistance to drugs used to treat certain types of acute myeloid leukemia (AML).

24 Oct 2016

Novel approach may speed up development of new drugs against skin disease

In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them.

21 Oct 2016

Rare neurological syndromes linked to variations in ATAD3A gene

A team of scientists from a number of institutions around the world, including Baylor College of Medicine, has discovered that rare neurological syndromes for which there was no cause can be the result of variations in the gene ATAD3A.

21 Oct 2016

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer.

21 Oct 2016

URI researchers design smart gloves to measure tremors and rigidity in Parkinson's patients

Prescribing a medication plan for a patient with Parkinson's disease is a big challenge for doctors, but now a University of Rhode Island biomedical engineering professor and his students are making great strides in solving that problem with their groundbreaking research.

21 Oct 2016

Scientists suggest potential approach of lowering tau levels to thwart Alzheimer's disease

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer's disease, according to scientists at Baylor College of Medicine, Texas Children's Hospital and Johns Hopkins University School of Medicine.

21 Oct 2016

Cedars-Sinai receives FDA approval to examine safety of combination stem cell-gene therapy in ALS patients

Cedars-Sinai regenerative medicine investigators have received approval from the U.S. Food and Drug Administration to test a combination stem cell-gene therapy they developed to stall the progression of amyotrophic lateral sclerosis, a neurological disease that causes progressive paralysis and ultimately death.

21 Oct 2016

Laboratory News and Research

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

TSRI scientists discover reason for lack of successful HCV vaccine design

Novel approach could help counter Influenza A virus in immune-compromised patients

Adult brain cells may be vulnerable to Zika infection, new study suggests

Choline deficiency in sows during pregnancy impacts nutrient composition of milk

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

Researchers identify negative role of oxidation in new blood cells

Danish researchers develop new method to study distribution of tracer in tumours

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Myriad Genetics and ION Solutions partner to provide accurate, comprehensive hereditary cancer tests

Systec to showcase comprehensive range of autoclaves at MEDICA 2016

FDA approves new fully automated blood analyzer for high-volume transfusion labs

PSH model of care provides better outcomes and decreases length of hospital stay

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Novel approach may speed up development of new drugs against skin disease

Rare neurological syndromes linked to variations in ATAD3A gene

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

URI researchers design smart gloves to measure tremors and rigidity in Parkinson's patients

Scientists suggest potential approach of lowering tau levels to thwart Alzheimer's disease

Cedars-Sinai receives FDA approval to examine safety of combination stem cell-gene therapy in ALS patients

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