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Implementation of value-driven outcomes tool in health care system can lead to lower costs, better quality

Implementing an analytic tool that allocates clinical care costs and quality measures to individual patient encounters was associated with significant improvements in value of care for 3 designated outcomes—total joint replacement, laboratory testing among medical inpatients, and sepsis management, according to a study appearing in the September 13 issue of JAMA.

14 Sep 2016

Belief about nicotine in cigarette may influence brain signals linked to cravings

Craving relief may depend more on the belief of satisfaction than actual relief, according to scientists at the Virginia Tech Carilion Research Institute and the Center for BrainHealth at The University of Texas at Dallas.

14 Sep 2016

Discovery of immune antibody could lead to development of improved influenza vaccines

Dana-Farber Cancer Institute investigators report they have discovered a type of immune antibody that can rapidly evolve to neutralize a wide array of influenza virus strains - including those the body hasn't yet encountered.

14 Sep 2016

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system.

14 Sep 2016

Study finds South Africans living with HIV more resilient despite chronic pain

When one thinks about chronic conditions that are commonly painful, HIV doesn't typically spring to mind. However, more than 50% of HIV-positive individuals experience a painful condition like headache, chest pain or neuropathy, and that pain is frequently experienced as moderate to severe in intensity.

14 Sep 2016

IRB Barcelona researchers reveal new strategy to obtain barrel-shaped amyloid-beta aggregates

Researchers at IRB Barcelona describe for the first time how to prepare a specific type of aggregate of the amyloid-beta protein with the ability to perforate the cell membrane.

14 Sep 2016

Researchers discover network of neural regions involved in spread of seizures

A flurry of coordinated activity in a brain-spanning network of neurons may sound like the formation of a brilliant new idea, but it is actually the description of a seizure. Understanding why and how this synchronization spreads would be a critical tool in treating severe epilepsy.

13 Sep 2016

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

For the 25 percent of type-2 diabetes patients who suffer from numbness and extreme nerve pain in their feet, a new dermatological treatment being tested by Northwestern Medicine scientists could potentially help prevent and maybe even reverse the neuropathy.

13 Sep 2016

Stiff, hypoxic regions of tumors trigger cancer progression

When Hippocrates first described cancer around 400 B.C., he referred to the disease's telltale tumors as "karkinos" -- the Greek word for crab.

13 Sep 2016

ATR inhibitors show improved survival and effectiveness in animal models of cancer

Tumours are an accumulation of cells that divide without control, accumulating hundreds of chromosomal alterations and mutations in their DNA.

13 Sep 2016

New scoring system may help expand pool of available kidneys in two ways

With over 120,000 patients in the United States waiting for a kidney transplant, scientists and physicians are constantly looking to expand the pool of available organs through increasing donation and optimizing allocation.

13 Sep 2016

Researchers develop novel technique to generate hiNSCs for multiple tissue engineering applications

Tufts University researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain, according to a paper published today in Stem Cell Reports

13 Sep 2016

Cold plasma therapy may help treat non-healing wounds

Russian scientists at the Moscow Institute of Physics and Technology, the Joint Institute for High Temperatures of the Russian Academy of Sciences, and Gamaleya Research Centre of Epidemiology and Microbiology found that treating cells with cold plasma leads to their regeneration and rejuvenation.

13 Sep 2016

Learning to downregulate amygdala activity could help gain control of emotional responses

Training the brain to treat itself is a promising therapy for traumatic stress. The training uses an auditory or visual signal that corresponds to the activity of a particular brain region, called neurofeedback, which can guide people to regulate their own brain activity.

12 Sep 2016

Study provides insight into how weight-loss drug acts in the brain

A weight-loss drug dampened the response to food cues in regions of the brain associated with attention and emotion, leading to decreases in caloric intake, weight and body mass index (BMI), a team led by scientists at Beth Israel Deaconess Medical Center reported.

12 Sep 2016

Cone snail venom could hold key to efficient therapies for diabetes

New research has found that venom extracted from a species of marine cone snail could hold the key to developing 'ultra-fast-acting' insulins, leading to more efficient therapies for diabetes management.

12 Sep 2016

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children's Hospital Los Angeles have isolated human nephron progenitor (NP) cells.

12 Sep 2016

Male signals trigger female animals for reproduction but with harmful effects

A research team led by a Northwestern University scientist has discovered that male animals, through their invisible chemical "essence," prime female animals for reproduction but with the unfortunate side effect of also hastening females' aging process.

12 Sep 2016

Rutgers researchers disprove eating dropped food within safe five-second window

Turns out bacteria may transfer to candy that has fallen on the floor no matter how fast you pick it up.

9 Sep 2016

Experts develop urine-based method to diagnose conditions in newborn babies

Experts from the V. I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology and the Moscow Institute of Physics and Technology have devised a method that uses the urinary proteome to diagnose conditions in newborn babies.

9 Sep 2016

Laboratory News and Research

Implementation of value-driven outcomes tool in health care system can lead to lower costs, better quality

Belief about nicotine in cigarette may influence brain signals linked to cravings

Discovery of immune antibody could lead to development of improved influenza vaccines

BET inhibitors could be powerful new therapeutic strategy for ovarian cancer

Study finds South Africans living with HIV more resilient despite chronic pain

IRB Barcelona researchers reveal new strategy to obtain barrel-shaped amyloid-beta aggregates

Researchers discover network of neural regions involved in spread of seizures

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

Stiff, hypoxic regions of tumors trigger cancer progression

ATR inhibitors show improved survival and effectiveness in animal models of cancer

New scoring system may help expand pool of available kidneys in two ways

Researchers develop novel technique to generate hiNSCs for multiple tissue engineering applications

Cold plasma therapy may help treat non-healing wounds

Learning to downregulate amygdala activity could help gain control of emotional responses

Study provides insight into how weight-loss drug acts in the brain

Cone snail venom could hold key to efficient therapies for diabetes

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

Male signals trigger female animals for reproduction but with harmful effects

Rutgers researchers disprove eating dropped food within safe five-second window

Experts develop urine-based method to diagnose conditions in newborn babies

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