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Women with ovarian cancer do not benefit from CA-125 and transvaginal ultrasound

In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened, according to a study in the June 8 issue of JAMA, a theme issue on cancer.

6 Jun 2011

Older adults with subclinical hyperthyroidism may face higher risk of dying

A common hormone abnormality in older adults—a mild form of overactive thyroid called subclinical hyperthyroidism—is linked to a much higher risk of dying, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

HRT reduces risk of breast cancer in women with BRCA mutations after ovary removal

Women with the BRCA1 or BRCA2 gene mutations, which are linked to a very high risk of breast and ovarian cancer, can safely take hormone-replacement therapy (HRT) to mitigate menopausal symptoms after surgical removal of their ovaries, according to new research from the Perelman School of Medicine at the University of Pennsylvania which will be presented Monday, June 6 during the American Society for Clinical Oncology's annual meeting.

4 Jun 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

A new therapy for type 1 diabetes? A promising treatment for deadly viruses? Does a common treatment for children with severe infection actually cause more harm than good? These are important questions being investigated by pediatric researchers at Mattel Children's Hospital UCLA.

4 Jun 2011

Hospitals need to measure quality of care

Hospitals that provide quality care for young people do not always provide the same quality care for the elderly, a new study has found.

4 Jun 2011

Research roundup: More spending can lead to better care; Calif. exchange lessons; high-volume hospitals

Medical Spending And The Health Of The Elderly -- Does more medical spending lead to better health care for people over age 64? To answer that question, "researchers from George Mason University and the Urban Institute used data of 17,438 elderly who entered the Medicare Current Beneficiary Survey in the fall of each year from 1991 to 1999, and conducted multiple interviews over three years," according to one description of the study.

4 Jun 2011

Many women over 70 with stage I breast cancer opt for radiation therapy: ASCO

Patterns of radiation usage in breast conserving therapy for women 70 years and older with stage I breast cancer are changing: more women are opting for radioactive implants and those with estrogen positive tumors are opting out of radiation therapy, according to an abstract being presented at the American Society of Clinical Oncology annual meeting in Chicago by Thomas Jefferson University Hospital researchers on Saturday, June 4.

3 Jun 2011

U-M study shows decline in surgery mortality for eight different high-risk operations

Surgery death rates have dropped nationwide over the past decade, according to a University of Michigan Health System study that reveals cancer surgeries have seen the most dramatic improvement in safety.

3 Jun 2011

New Kaiser Family Foundation tool shows which global health interventions are working

Today, the Kaiser Family Foundation unveiled an innovative, online tool that allows users to learn quickly and easily about which global health interventions work. The Global Health Intervention Review (GHIR) compiles the latest information on the efficacy of key global health interventions, including the strength of the evidence, and presents the information in a variety of accessible formats. Users can view a comprehensive overview and a key findings table.

2 Jun 2011

Relatives of women who died in childbirth in Uganda sue government

"Relatives of two woman who died in childbirth launched a landmark lawsuit against the Ugandan government Friday to highlight the failure to provide adequate maternal healthcare," Sapa/Agence France-Presse/IOL reports.

2 Jun 2011

Cardiac resynchronization therapy improves sexual health in men with chronic heart failure

A new study published in the journal Clinical Cardiology reveals that in men with chronic heart failure, cardiac resynchronization therapy improves patients' libido, erectile dysfunction, and sexual performance.

2 Jun 2011

HbA1c glucose monitoring test not effective for diagnosing diabetes patients with kidney failure

The gold standard long-term glucose monitoring test for patients with diabetes proved to be of limited value in dialysis patients, according to a new study at Wake Forest Baptist Medical Center.

1 Jun 2011

Hospitals facing pressure to hold down costs and cut infections; drug shortages reported

For the first time in its history, Medicare will soon track spending on millions of individual beneficiaries, reward hospitals that hold down costs and penalize those whose patients prove most expensive. The administration plans to establish "Medicare spending per beneficiary" as a new measure of hospital performance, just like the mortality rate for heart attack patients and the infection rate for surgery patients.

1 Jun 2011

Bowel cancer strikes early - strikes hard

Recent figures show that the incidence of bowel cancer in young people has surged in the past decade, more than doubling in some age categories. But doctors have been unable to explain the increase.

1 Jun 2011

First Edition: May 31, 2011

Today's headlines include articles on the federal efforts to improve hospital quality, the politics of Medicare and the move by some GOP governors to set up health exchanges.

31 May 2011

Novel treatment safe and effective for patients with intracerebral hemorrhage

A new treatment that treats a subset of stroke patients by combining minimally invasive surgery, an imaging technique likened to "GPS for the brain," and the clot-busting drug t-PA appears to be safe and effective, according to a multicenter clinical trial led by Johns Hopkins researchers.

30 May 2011

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

5% to 10% of all breast cancers are monogenic in origin. In other words, there is a mutation of the genes BRCA1, BRCA2 or other high-risk genes. In this edition of Deutsches Ärzteblatt International, Alfons Meindl of the Klinikum rechts der Isar and coauthors report on new insights into the pathogenesis and treatment of hereditary breast and ovarian cancer and newly-discovered risk genes.

30 May 2011

Research Roundup: Medicaid co-payments, access to docs causes worse health

Disparities In Child Access To Emergency Care For Acute Oral Injury -- This study looked at the "impact of insurance status on dental practices' willingness to schedule an appointment for a child with a symptomatic fractured permanent front tooth." Six researchers posed as mothers of 10-year-old boys who all had the same injury but different coverage: Medicaid/Children's Health Insurance Program (CHIP) or private Blue Cross dental insurance.

27 May 2011

Molecular mechanism of selected autophagy elucidated

Salmonella is widely prevalent in the animal kingdom. The reason we do not suffer from severe intestinal infections very often is due to our body's defence system, which manages to digest invading bacteria. This is why, generally speaking, a healthy human being will only fall ill if he consumes more than 100.000 salmonella bacteria via a contaminated food source, such as eggs or meat.

27 May 2011

WGO to focus on diarrheal disease prevention, management during World Digestive Health Day

Diarrheal disease, a common gastrointestinal problem with potentially fatal implications in the developing world is the focus of World Digestive Health Day on May 29. Infections that cause diarrhea are serious public health challenges, both in the United States and globally.

27 May 2011

Mortality News and Research

Women with ovarian cancer do not benefit from CA-125 and transvaginal ultrasound

Older adults with subclinical hyperthyroidism may face higher risk of dying

HRT reduces risk of breast cancer in women with BRCA mutations after ovary removal

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

Hospitals need to measure quality of care

Research roundup: More spending can lead to better care; Calif. exchange lessons; high-volume hospitals

Many women over 70 with stage I breast cancer opt for radiation therapy: ASCO

U-M study shows decline in surgery mortality for eight different high-risk operations

New Kaiser Family Foundation tool shows which global health interventions are working

Relatives of women who died in childbirth in Uganda sue government

Cardiac resynchronization therapy improves sexual health in men with chronic heart failure

HbA1c glucose monitoring test not effective for diagnosing diabetes patients with kidney failure

Hospitals facing pressure to hold down costs and cut infections; drug shortages reported

Bowel cancer strikes early - strikes hard

First Edition: May 31, 2011

Novel treatment safe and effective for patients with intracerebral hemorrhage

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

Research Roundup: Medicaid co-payments, access to docs causes worse health

Molecular mechanism of selected autophagy elucidated

WGO to focus on diarrheal disease prevention, management during World Digestive Health Day

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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