Immune System News and Research

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Possible risk factors for brain aneurysm development in adults living with HIV

With advances in antiretroviral therapy (ART), outcomes for adults living with human immunodeficiency virus (ALWH) have largely improved, drastically decreasing the risk of death from opportunistic infections.

26 Apr 2023

Understanding how biological sex and immune system contribute to shaping the developing brain

Researchers have established that biological sex plays a role in determining an individual's risk of brain disorders.

26 Apr 2023

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

26 Apr 2023

Understanding the cervical microbiome: a promising frontier in HPV treatment

A recent feature published in PNAS provided emerging insights into microflora associated with human papillomavirus (HPV) infections.

26 Apr 2023

Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

For 30% to 40% of lymphoma patients who receive CAR T therapy, the treatment is a godsend.

25 Apr 2023

Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

A new approach to chimeric antigen receptor T-cell (CAR T) therapy has shown great promise against small cell lung cancer (SCLC) in a preclinical study.

25 Apr 2023

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity.

25 Apr 2023

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

The first in-human-study of a new immunotherapy that blocks a natural enzyme tumors commandeer for their protection was well tolerated by children with relapsed brain tumors and enabled many to have unexpected months of a more normal life, researchers say.

25 Apr 2023

New class of immunotherapy shows promise against aggressive skin cancer

A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.

25 Apr 2023

Depressed? Anxious? Air pollution may be a factor

In the 1990s, residents of Mexico City noticed their dogs acting strangely — some didn't recognize their owners, and the animals' sleep patterns had changed.

25 Apr 2023

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Researchers reviewed the impact of ultra-processed foods (UPFs) on the microbiota-gut-brain axis.

25 Apr 2023

Improving cancer treatment outcomes: the potential use of fermented food interventions

Researchers reviewed the use of fermented food interventions to alter the gut microbiome composition and improve immunotherapy.

25 Apr 2023

Novel gel offers hope for patients with glioblastoma

Medication delivered by a novel gel cured 100% of mice with an aggressive brain cancer, a striking result that offers new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans.

24 Apr 2023

Maintaining normal vitamin D levels may benefit patients receiving anti-cancer immunotherapy

New research indicates that for patients with advanced skin cancer, it may be important to maintain normal vitamin D levels when receiving immunotherapy medications called immune checkpoint inhibitors.

24 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

RSV infection in the first year of life associated with increased risk of childhood asthma

Severe respiratory syncytial virus (RSV) infection has long been associated with the onset of childhood wheezing diseases, but the relationship between RSV infection during infancy and the development of childhood asthma has remained unclear.

24 Apr 2023

Bioengineered drug candidate can counter S. aureus infection in early tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

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Immune System News and Research

Possible risk factors for brain aneurysm development in adults living with HIV

Understanding how biological sex and immune system contribute to shaping the developing brain

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

Understanding the cervical microbiome: a promising frontier in HPV treatment

Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

Previously unknown mechanisms may lead to new approaches to fight viral infections

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

New class of immunotherapy shows promise against aggressive skin cancer

Depressed? Anxious? Air pollution may be a factor

Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications?

Improving cancer treatment outcomes: the potential use of fermented food interventions

Novel gel offers hope for patients with glioblastoma

Maintaining normal vitamin D levels may benefit patients receiving anti-cancer immunotherapy

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

RSV infection in the first year of life associated with increased risk of childhood asthma

Bioengineered drug candidate can counter S. aureus infection in early tests

Deciphering immunological imprinting in the context of COVID-19

Researchers develop a backpack-based myeloid cell therapy for MS patients

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