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Approaches designed to motivate drug development for children needed

Recent legislative and regulatory actions make great strides toward establishing much needed incentives for pharmaceutical companies and others to develop and test more medications for pediatric rare diseases, including pediatric cancers, according to commentary by experts from Children's National Medical Center. The commentary appears in the January 19 issue of Science Translational Medicine.

21 Jan 2011

Math may help assess how rapidly stem cells and cancer-causing cousins increase numbers

The difficult task of sorting and counting prized stem cells and their cancer-causing cousins has long frustrated scientists looking for new ways to help people who have progressive diseases.

21 Jan 2011

inVentiv Health to acquire Campbell Alliance and i3

inVentiv Health, Inc., a leading provider of outsourced clinical development, launch and commercialization services to the global healthcare industry, today announced that it has signed a definitive agreement to acquire Campbell Alliance, a leading management consulting firm specializing in serving the pharmaceutical and biotech industries. Yesterday, inVentiv announced that it has signed a definitive agreement to purchase i3 from Ingenix.

From Thermo Fisher Scientific Inc. 21 Jan 2011

How Dems who voted against the health law decided their repeal positions

Three House Democrats voted with Republicans to repeal the health law. But others, who voted against the legislation the first time around, chose to side with their party caucus.

21 Jan 2011

EMA CHMP issues negative opinion against Biogen Idec's FAMPYRA for multiple sclerosis

Biogen Idec announced today that the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has issued a negative opinion recommending against approval of FAMPYRA to improve walking ability in adult patients with multiple sclerosis (MS) in the European Union. Biogen Idec intends to appeal this opinion and request a re-examination of the decision by the CHMP.

21 Jan 2011

Researchers map complex choreography used by immune system's T cells to recognize pathogens

Researchers have for the first time mapped the complex choreography used by the immune system's T cells to recognize pathogens while avoiding attacks on the body's own cells.

21 Jan 2011

What protects certain diabetics from complications?

Much research has been carried out on why diabetics develop complications. Now researchers are asking the question the other way around. They want to know why some diabetic patients do not develop complications. What is it that protects them? The PROLONG study could provide the answer.

21 Jan 2011

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

The anti-diuretic hormone "vasopressin" is released from the brain, and known to work in the kidney, suppressing the diuresis.

21 Jan 2011

Researchers discover several key mutations in pancreatic neuroendocrine tumors

Through a grant provided by the Caring for Carcinoid Foundation, researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center have discovered several key mutations in pancreatic neuroendocrine tumors.

21 Jan 2011

MedImmune announces MEDI-573 preclinical results against many solid tumors

MedImmune's Oncology group announced today preclinical results showing that MEDI-573, a targeted monoclonal antibody, broadly suppresses pathways that have been shown to play a critical role in the development and progression of many solid tumors.

21 Jan 2011

WSJ: Insurers' profits on the rise

Health insurers' fourth-quarter reports will provide an early glimpse into how much wind the health overhaul could take out of plans' profits—and, so far, Wall Street estimates don't look all that bad for the industry (Johnson, 1/20).

21 Jan 2011

Study highlights relationship between language and health care quality

Wayne State University researchers have found that when patients and providers speak the same language, patients report less confusion and better health care quality.

21 Jan 2011

U.S., China announce public-private health care partnership

In conjunction with the state visit to the U.S. by Chinese President Hu Jintao, the U.S. Department of Health and Human Services (HHS) and several other federal agencies on Wednesday announced a new public-private health care partnership between the U.S. and China, Modern Healthcare reports (Blesch, 1/19).

21 Jan 2011

Precision highlights role of ChemoFx test, multi-gene predictors for breast cancer

In a new study in which Precision Therapeutics' Multi-Gene Predictors were independently validated by investigators at US Oncology and MD Anderson, Precision highlights the potential role of the ChemoFx® in vitro chemosensitivity test and multi-gene predictors in determining a patient's likelihood of response to multi-drug chemotherapy regimens in breast cancer.

21 Jan 2011

House GOP passes health law repeal

In what is considered to be a symbolic vote, House Republicans joined with three Democrats to fulfill a campaign pledge to pass a bill that would undo the sweeping health overhaul.The vote represented the Republican House majority's first official rebuke of the Obama agenda. Senate action, however, is unlikely.

21 Jan 2011

Scientist receives RO1 research grant to improve blood, marrow transplantation in myeloma patients

Thea Friedman, M.D., associate scientist and director of oncology basic research at the John Theurer Cancer Center at Hackensack University Medical Center was recently awarded a National Cancer Institutes of Health-National Cancer Institute RO1 research grant to improve allogeneic blood and marrow transplantation for multiple myeloma patients.

21 Jan 2011

Adopting pharmacy carve-in approach can help 13 states realize over $11 billion savings in Medicaid

A study sponsored by Medicaid Health Plans of America (MHPA) released today by The Lewin Group finds large-scale savings can be achieved if 13 states abandoned their current pharmacy carve-out model in favor of a carve-in approach -- including prescription drugs in health plans' capitation payments.

21 Jan 2011

WHO executive board meeting addresses agency's policy on counterfeit, substandard medications

According to the news service, WHO "members … raised strong concerns that a working group they mandated last May to address problems with WHO policy on counterfeit and substandard medicines has yet to be formed - with four months remaining before it must report back to members."

21 Jan 2011

AHRQ finds 30% increase in Medicaid-covered patient hospital admissions

Hospital admissions of patients covered by Medicaid jumped by 30 percent between 1997 and 2008, compared to a 5 percent growth in those of patients with private health insurance, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

21 Jan 2011

Religious hospitals' restrictions sparking conflicts, scrutiny, The Washington Post reports

Such disputes between hospitals and church authorities appear to be arising because of a confluence of factors: Economic pressures are spurring greater consolidation in the hospital industry, prompting religiously affiliated institutions to take over or merge with secular ones, imposing church directives on them.

21 Jan 2011

Research News and Research

Approaches designed to motivate drug development for children needed

Math may help assess how rapidly stem cells and cancer-causing cousins increase numbers

inVentiv Health to acquire Campbell Alliance and i3

How Dems who voted against the health law decided their repeal positions

EMA CHMP issues negative opinion against Biogen Idec's FAMPYRA for multiple sclerosis

Researchers map complex choreography used by immune system's T cells to recognize pathogens

What protects certain diabetics from complications?

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

Researchers discover several key mutations in pancreatic neuroendocrine tumors

MedImmune announces MEDI-573 preclinical results against many solid tumors

WSJ: Insurers' profits on the rise

Study highlights relationship between language and health care quality

U.S., China announce public-private health care partnership

Precision highlights role of ChemoFx test, multi-gene predictors for breast cancer

House GOP passes health law repeal

Scientist receives RO1 research grant to improve blood, marrow transplantation in myeloma patients

Adopting pharmacy carve-in approach can help 13 states realize over $11 billion savings in Medicaid

WHO executive board meeting addresses agency's policy on counterfeit, substandard medications

AHRQ finds 30% increase in Medicaid-covered patient hospital admissions

Religious hospitals' restrictions sparking conflicts, scrutiny, The Washington Post reports

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