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TMEM106B gene appears to protect against frontotemporal lobar degeneration

Neuroscientists had assumed that a mutation in the progranulin gene, which makes the progranulin protein and supports brain neurons, was sufficient to produce a kind of dementia known as frontotemporal lobar degeneration. But now an international team of scientists led by researchers at Mayo Clinic's campus in Florida have found another genetic factor they say appears to protect against the disorder in progranulin mutation carriers.

23 Dec 2010

Bloomberg: The politics, investments of judges

Three federal judges overseeing challenges to the Obama administration's health-care overhaul own shares of companies in the industry, including insurers and medical-device makers, the government watchdog group Center for Public Integrity reported.

23 Dec 2010

FDA approves Novartis' Amturnide for treatment of high blood pressure

Today Novartis announced that the US Food and Drug Administration (FDA) approved Amturnide (aliskiren, amlodipine and hydrochlorothiazide) tablets for the treatment of high blood pressure. Amturnide combines the only approved direct renin inhibitor worldwide, Tekturna (aliskiren), with the widely used calcium channel blocker amlodipine and the diuretic hydrochlorothiazide (HCTZ).

23 Dec 2010

Immunomedics announces additional claim for RS7 antibodies patent family

Immunomedics, a biopharmaceutical company primarily focused on the development of monoclonal antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases, today announced that additional claims for the patent family, "RS7 antibodies," were issued as Patent No. 1,002,443 in Korea.

23 Dec 2010

Today's Opinions: Congressional funding vote leaves out health law; Price controls on health; Tough choices in Washington State

The Senate passed the Continuing Resolution 79-16 this afternoon. Another way of saying that: The Senate voted to defund the implementation of both health-care reform and financial-regulation reform.

23 Dec 2010

Minorities with MS may face risk of developing depressive symptoms

Multiple sclerosis can cause significant physical impairment, including fatigue, pain, muscle spasms, tremors and dizziness. For many with MS, the disease wreaks havoc with emotional well-being, too, and according to a new study, minorities might especially be at risk for developing depressive symptoms.

23 Dec 2010

People with high RBC folate levels more likely to have two tumor-suppressing genes

People with higher levels of folate in their red blood cells were more likely to have two tumor-suppressing genes shut down by methylation, a chemical off switch for genes, researchers report in the December issue of Cancer Prevention Research.

22 Dec 2010

Researchers identify class of drugs that can promote RBC formation in anemic patients

By determining how corticosteroids act to promote red blood cell progenitor formation, Whitehead Institute researchers have identified a class of drugs that may be beneficial in anemias, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

22 Dec 2010

New nanoparticle-based diagnostic platform provides rapid detection of sepsis

Blood poisoning can be fatal. If you suffer from sepsis, you used to have to wait as much as 48 hours for laboratory findings. A new diagnostic platform as big as a credit card will now supply the analysis after as little as an hour. This system is based on nanoparticles that are automatically guided by magnetic forces.

22 Dec 2010

Researchers perform cord blood cell transplantation to treat child with ischemic brain injury

In three monthly injections, researchers transplanted neurally-committed, autologous cord blood derived cells tagged with iron oxide nanoparticles into the lateral cerebral ventricle of a 16-month old child with severe global hypoxic ischemic brain injury.

22 Dec 2010

Gene changes during brain development can lead to male genitalia formation in female embryo

Australian scientists have discovered that changes to a gene involved in brain development can lead to testis formation and male genitalia in an otherwise female embryo.

22 Dec 2010

New era for anticoagulant therapy

In a Guest Editorial published in the new publication Clinical Investigation, Dr Jeffrey Weitz and Dr John Eikelboom of McMaster University in Hamilton, Canada highlight the importance of the approval in October by the FDA of dabigatran etexilate (Pradaxa®; Boehringer Ingelheim). This new oral thrombin inhibitor provides an alternative to warfarin for long-term stroke prevention in patients with non-valvular atrial fibrillation.

22 Dec 2010

Children with autism may have problem with visual skills: Study

A new study suggests that children with autism may lack certain visual skills needed to be independent in adulthood. Researchers at the University of Bristol in the United Kingdom said they might find it difficult to spot something.

22 Dec 2010

NIH Clinical Center opens doors to Damon Runyon Clinical Investigators

A new pilot partnership between the National Institutes of Health Clinical Center, the National Cancer Institute's Center for Cancer Research, and the Damon Runyon Cancer Research Foundation will offer some of the capabilities and expertise of America's research hospital to an external group of clinical investigators in cancer research. The special talent and resources of the NIH will allow Damon Runyon-funded investigators to undertake studies and collaborations that will advance understanding of the prevention, diagnosis, and treatment of cancer.

22 Dec 2010

Vote For Kids Health calls for voting support to help win December Pepsi Refresh Project

Critically ill and disadvantaged children are counting on the generosity of strangers Thursday, December 23, 2010, asking for 100,000 votes to help win their grant ideas in the December Pepsi Refresh Project. Securing the thousands of votes needed to finish in winning spots is an uphill challenge for many organizations, but eight enterprising charities have joined forces to help each other into the winners circle.

22 Dec 2010

First Edition: December 22, 2010

Today's headlines include a number of reports regarding a new proposed rule by the Department of Health and Human Services that will require insurers to justify large premium hikes.

22 Dec 2010

RadNet to acquire Imaging On Call

RadNet, Inc., a national leader in providing high-quality, cost-effective, fixed-site outpatient diagnostic imaging services through a network of 198 fully-owned and operated outpatient imaging centers, today reported it has executed a definitive agreement to acquire Imaging On Call, LLC for $5.5 million plus contingent compensation of up to an additional $2.5 million if Imaging On Call achieves certain 2011 performance milestones.

22 Dec 2010

Virtual technology to train social workers to help address mental health needs of veterans

Real-life application of revolutionary virtual technology to train and teach in the classroom will be the focus of the University of Southern California's display and presentations at the Consumers Electronics Show (CES) Jan. 6-10 at the Las Vegas Convention Center.

22 Dec 2010

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Using fruit flies as a model to study embryo formation, scientists report in Nature Cell Biology that molecular breakdown of a protein called Bicoid is vital to normal head-to-tail patterning of the insect's offspring.

22 Dec 2010

Global Business Forum on health care at University of Miami

The University of Miami will bring together some of the most influential leaders in business and government, along with hundreds of professionals from across industries, Jan. 12 - 14, 2011 for a Global Business Forum entitled "The Business of Health Care: Defining the Future."

22 Dec 2010

Research News and Research

TMEM106B gene appears to protect against frontotemporal lobar degeneration

Bloomberg: The politics, investments of judges

FDA approves Novartis' Amturnide for treatment of high blood pressure

Immunomedics announces additional claim for RS7 antibodies patent family

Today's Opinions: Congressional funding vote leaves out health law; Price controls on health; Tough choices in Washington State

Minorities with MS may face risk of developing depressive symptoms

People with high RBC folate levels more likely to have two tumor-suppressing genes

Researchers identify class of drugs that can promote RBC formation in anemic patients

New nanoparticle-based diagnostic platform provides rapid detection of sepsis

Researchers perform cord blood cell transplantation to treat child with ischemic brain injury

Gene changes during brain development can lead to male genitalia formation in female embryo

New era for anticoagulant therapy

Children with autism may have problem with visual skills: Study

NIH Clinical Center opens doors to Damon Runyon Clinical Investigators

Vote For Kids Health calls for voting support to help win December Pepsi Refresh Project

First Edition: December 22, 2010

RadNet to acquire Imaging On Call

Virtual technology to train social workers to help address mental health needs of veterans

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Global Business Forum on health care at University of Miami

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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