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Global Fund approves 79 grants with two-year commitment of $1.7B

The Global Fund to Fight AIDS, Tuberculosis and Malaria Board of Directors on Wednesday approved 79 grants with a two-year commitment of "$1.7 billion dollars for projects against the diseases, amid warnings that some hard-hit African countries were being left out," Agence France-Presse reports. The commitment, according to Ethiopian Health Minister Tedros Adhanom Ghebreyesus, who chairs the Global Fund's board, "shows that even in hard economic times, we can continue to expand the fight against the three diseases" (12/15).

17 Dec 2010

Catalyst receives $4.0M milestone payment from Pfizer under hemophilia Factor VIIa program

Catalyst Biosciences, Inc., the leading company in the discovery and development of engineered proteases, today announced the receipt of a $4.0 million milestone payment from Pfizer Inc. under the terms of the collaboration agreement for the development of improved recombinant human Factor VIIa variants for the treatment of hemophilia and other bleeding disorders.

17 Dec 2010

Study suggests blood test may detect persons with CKD

An infrequently used blood test can effectively identify individuals at increased risk of developing complications associated with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

17 Dec 2010

MDA awards Repligen $1.4M for research of new compound with therapeutic potential for SMA

The Muscular Dystrophy Association today announced it has awarded $1.4 million in new research funding to the biopharmaceutical firm Repligen of Waltham, Mass., to complete the preclinical work needed to begin human clinical trials of a promising therapeutic compound for spinal muscular atrophy (SMA).

17 Dec 2010

Merck, sanofi-aventis enter global cancer research and development agreement

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that Merck, has signed a worldwide research and development agreement with sanofi-aventis U.S. Inc., under which Merck Serono and sanofi-aventis U.S. Inc. will collaboratively investigate novel experimental combinations of agents that could block specific pathways in cancer cells. This collaboration could deliver novel targeted oncology treatments with high therapeutic potential.

17 Dec 2010

Researchers discover new molecular mechanism of Alzheimer's disease through protein interaction

Through a complex analysis of protein interactions, researchers from IRB Barcelona and the Joint Programme IRB-BSC have discovered new molecular mechanisms that may be involved in the development of Alzheimer's disease.

17 Dec 2010

President signs one-year 'pay-fix'; Medicare tests competitive bidding for common medical equipment

The Kansas City Star reports on a new Medicare program that will apply competitive bidding to common medical equipment and supplies. Meanwhile, President Obama signed into law yesterday a one-year delay in Medicare payment cuts for physicians.

17 Dec 2010

Pediatric cancer researchers study medulloblastoma for new treatment

Pediatric cancer researchers at The Children's Hospital of Philadelphia contributed important expertise to a new landmark study of medulloblastoma, a type of brain tumor typically found in children.

17 Dec 2010

Human fetal immune system entirely different from adult immune system

UCSF researchers have shown for the first time that the human fetal immune system arises from an entirely different source than the adult immune system, and is more likely to tolerate than fight foreign substances in its environment.

17 Dec 2010

Alnylam Pharmaceuticals progress in delivery and translation of RNAi therapeutics

Alnylam Pharmaceuticals, a leading RNAi therapeutics company, presented new data at the 2010 International Chemical Congress of Pacific Basin Societies, being held in Honolulu, Hawaii, December 15-20.

17 Dec 2010

U.S., South Africa sign PEPFAR partnership agreement

Secretary of State Hillary Rodham Clinton and South African International Relations and Cooperation Minister Maite Nkoana-Mashabane on Tuesday signed a "partnership agreement that will guide efforts on fighting HIV/AIDS in the African nation," Bloomberg BusinessWeek reports (Wessels, 12/15).

17 Dec 2010

First comprehensive guide to hospital emergency preparedness exercise development

With the publication of the nation's first comprehensive, federally funded guide to hospital emergency preparedness exercise development, Dr. Nathaniel Hupert at Weill Cornell Medical College and his collaborators have provided a new toolset for strengthening hospitals' ability to protect communities nationwide against public health disasters, such as creating care centers during an influenza pandemic or treating casualties in the wake of a bioterrorism attack.

17 Dec 2010

Genetic biomarker linked to increased risk for breast cancer found in 'junk' DNA

A new genetic biomarker that indicates an increased risk for developing breast cancer can be found in an individual's "junk" (non-coding) DNA, according to a new study featuring work from researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues.

17 Dec 2010

White House to hold meetings with stakeholders on overhaul implementation

News outlets offer reports about action on the implementation front, including White House stakeholder meetings and a vote by state insurance officials regarding the information health plans should provide consumers.

17 Dec 2010

AFFiRiS AG receives 475,000 MJFF grant for Parkinson vaccine development

With a grant of USD 475,000, the Michael J. Fox Foundation is funding preclinical development of a vaccine against Parkinson's disease by AFFiRiS AG. The vaccine, known as PD01, targets the protein alpha-synuclein and might offer for the first time a possibility for a treatment that can slow or stop the progression of Parkinson's disease.

17 Dec 2010

Study: Biomarkers may aid in early diagnosis of breast cancer

Using a new, powerful method for rapidly screening molecules associated with disease, proteomics expert Joshua LaBaer and colleagues from the Biodesign Institute at Arizona State University have identified a broad panel of 28 early predictors, or biomarkers, that may one day aid in the early diagnosis of breast cancer.

17 Dec 2010

Iowa moves forward on health exchange; Texas medical school highlights geriatrics; Concerns grow about prisoners' mental health needs

Republican lawmakers on the state level are largely against the new health reform law—but they aren't against all of the behemoth legislation. Virginia dominated headlines this week when a federal judge ruled the individual mandate to buy insurance unconstitutional on Monday. Much less noticed: the very next day, a task force appointed by Republican Gov. Bob McDonnell recommended that the state implement a health insurance exchange earlier than federal guidelines require (Kliff, 12/16).

17 Dec 2010

Accelr8 reports $466,362 net sales revenue for first fiscal quarter ended October 31, 2010

Accelr8 Technology Corporation announced its financial results for the first fiscal quarter ended October 31, 2010. Net sales revenues totaled $466,362; net income from operations was $49,974 with total net income of $67,250. For the previous quarter, net sales were $15,549 with a loss from operations of $(423,373) and a total net loss of $(411,981). Shareholders' equity totaled $4,985,682 at the current quarter's end, up from $4,909,778 at the end of the previous fiscal quarter.

17 Dec 2010

Florida Judge hears arguments in 20-state health law challenge; says ruling will take time

The Associated Press: Attorneys for 20 states involved in a challenge to the new health law argued Thursday morning before U.S. District Judge Roger Vinson that it will "expand the government's powers in dangerous and unintended ways." The states were seeking "a summary judgment throwing out the health care law without a full trial. They argue it violates people's rights by forcing them to buy health insurance by 2014 or face penalties."

17 Dec 2010

Collaboration seeks to uncover the best strategies to improve health care, lower costs

A group of health care organizations are joining forces to compile evidence on the strategies the work best to address a variety of common, and usually expensive, medical conditions. Meanwhile, the nation's new Medicare chief is hitting the road to hear ideas about improving the health care system.

17 Dec 2010

Research News and Research

Global Fund approves 79 grants with two-year commitment of $1.7B

Catalyst receives $4.0M milestone payment from Pfizer under hemophilia Factor VIIa program

Study suggests blood test may detect persons with CKD

MDA awards Repligen $1.4M for research of new compound with therapeutic potential for SMA

Merck, sanofi-aventis enter global cancer research and development agreement

Researchers discover new molecular mechanism of Alzheimer's disease through protein interaction

President signs one-year 'pay-fix'; Medicare tests competitive bidding for common medical equipment

Pediatric cancer researchers study medulloblastoma for new treatment

Human fetal immune system entirely different from adult immune system

Alnylam Pharmaceuticals progress in delivery and translation of RNAi therapeutics

U.S., South Africa sign PEPFAR partnership agreement

First comprehensive guide to hospital emergency preparedness exercise development

Genetic biomarker linked to increased risk for breast cancer found in 'junk' DNA

White House to hold meetings with stakeholders on overhaul implementation

AFFiRiS AG receives 475,000 MJFF grant for Parkinson vaccine development

Study: Biomarkers may aid in early diagnosis of breast cancer

Iowa moves forward on health exchange; Texas medical school highlights geriatrics; Concerns grow about prisoners' mental health needs

Accelr8 reports $466,362 net sales revenue for first fiscal quarter ended October 31, 2010

Florida Judge hears arguments in 20-state health law challenge; says ruling will take time

Collaboration seeks to uncover the best strategies to improve health care, lower costs

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Automating research - solutions and best practices

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