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Presence of circulating tumor cells in early-stage breast cancer doubles risk of relapse and death

The presence of one to four circulating tumor cells (CTCs) in the blood of early-stage breast cancer patients almost doubled patient's risk of cancer relapse and death, and five or more CTCs increased recurrence by 400 percent and death by 300 percent, according to Phase III results of the SUCCESS trial. These cells were found in patients after surgery but before chemotherapy treatment.

13 Dec 2010

New groundbreaking research advances understanding of HIV

It is estimated that 38 million people worldwide are currently infected with HIV and that 4.1 million more are added each year. For scientists to design treatment therapies that are effective over the long-term it is essential to learn more about how the virus mutates and develops resistance to medications.

13 Dec 2010

News outlets examine flooding in Pakistan four months on

"More than four months after the worst flooding in Pakistan's history, vast stretches of land are still under water in the province of Sindh, isolating many communities. ... The world's attention has long since moved on from the Pakistani flood story, but there are still more than 1 million people who remain displaced in Sindh alone, said U.N. humanitarian affairs chief Valerie Amos last Friday after touring the flood zone.

13 Dec 2010

Higher co-payments lead to early discontinuation of life-saving therapy for breast cancer

A higher prescription co-payment, especially among older women, is associated with both early discontinuation and incomplete use of adjuvant aromatase inhibitor therapy, a life-saving therapy for women with hormone sensitive early stage breast cancer.

13 Dec 2010

New DNA-based testing technology for tuberculosis treatment

The driving force behind the rapid tuberculosis test that received World Health Organization endorsement this week is Dr. David Alland, chief of the Division of Infectious Disease at UMDNJ-New Jersey Medical School.

13 Dec 2010

EMEA calls for Europe-wide ban on blood donation from ME/CFS patients

The European ME Alliance (EMEA) is calling on Europe's health ministers to initiate an immediate Europe-wide prohibition of blood donation from people who have been diagnosed with myalgic encephalomyelitis (ME/CFS).

13 Dec 2010

Small amounts of mobility can reduce hospital stay for elderly patients

"You'll be back on your feet in no time" is a phrase familiar to anyone who's ever had to spend time in a hospital. Now, a new study has shown that hospitalized elderly patients who literally "get back on their feet" by taking even short walks around a hospital unit tend to leave the hospital sooner than their more sedentary peers.

13 Dec 2010

Lowering legal drinking age would be ineffective in reducing binge drinking in colleges

Although presidents at some U.S. colleges have argued that lowering the minimum legal drinking age could help curb binge drinking on campuses, a new study in the January issue of the Journal of Studies on Alcohol and Drugs suggests such a measure would be ineffective.

13 Dec 2010

Xeloda may reduce recurrence of faster growing breast cancers: Study

Joyce O'Shaughnessy, M.D., medical director and co-chair of the Breast Cancer Research Committee, US Oncology Research, and medical oncologist with Texas Oncology-Baylor Sammons Cancer Center, presented her study findings today at the 33rd Annual San Antonio Breast Cancer Symposium (SABCS), an international scientific symposium for interaction and exchange among basic scientists and clinicians in breast cancer

13 Dec 2010

Study finds Haitian cholera strain resembles one from South Asia, carries mutation that increases severity

"Detailed genetic tests confirm that the cholera strain that has killed more than 2,000 people in Haiti came from South Asia and most closely resembles a strain circulating in Bangladesh," according to a study published Thursday in the New England Journal of Medicine (NEJM), Reuters reports (12/9).

13 Dec 2010

New initiative launched to fight cystic fibrosis

The University of British Columbia, in partnership with the Canadian Cystic Fibrosis Foundation (CCFF) and the Centre for Drug Research and Development (CDRD), today launches the Cystic Fibrosis Technology Initiative (CFTI) to advance Canadian technologies that will help combat cystic fibrosis (CF).

13 Dec 2010

Research programs embody the promise of anti-aging medicine.

Sometimes the value of research lies as much in exposing false remedies as in discovering true breakthroughs. Scientists at the country's first school of gerontology and in laboratories around the University of Southern California do both, mindful of their responsibility to a society focused on healthful aging.

13 Dec 2010

Combination therapy improves tumor response in HER2-positive breast cancer patients

A combination of lapatinib, trastuzumab and paclitaxel significantly improved tumor response rates than either agent alone among patients with HER2-positive breast cancers, according to data presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

More sensitive screening tests needed to reduce ovarian cancer deaths

The best currently available screening tests can only slightly reduce ovarian cancer deaths. That is the conclusion of new research published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The results suggest that strategies other than screening, such as prevention and better treatments, will be needed to significantly lower the number of women who die from ovarian cancer.

13 Dec 2010

Prostate cancer study identifies 295 genes associated with clinical recurrence following radical prostatectomy

Genomic Health, Inc. today announced the first results of a large prostate cancer study that identified 295 genes strongly associated with clinical recurrence following radical prostatectomy. Top-line findings from this study, which applied the same RT-PCR technology used in Genomic Health's Oncotype DX® breast and colon cancer tests, will be presented today at the Society for Urologic Oncology (SUO) annual meeting.

13 Dec 2010

UAB researchers pinpoint protein that causes nephrotic syndrome

University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition.

13 Dec 2010

Rate of health care-associated infections in developing countries more than double U.S., European rates, study finds

The rate of health care-associated infections in developing countries is more than three times the rate of cases in the U.S. and more than double the rate in Europe, according to a study published Friday in the Lancet, BBC reports (12/9).

13 Dec 2010

Multi-unit dwellings contribute to children's exposure to tobacco smoke

Children living in apartments are exposed to secondhand smoke even when no one smokes inside their own unit. This study, released online today by the journal Pediatrics, strongly suggests that housing type contributes to children's exposure to tobacco smoke, despite the best intentions of parents.

13 Dec 2010

Novelos NOV-002 demonstrates positive results in Phase 2 neoadjuvant breast cancer trial

Novelos Therapeutics, Inc., a biopharmaceutical company developing therapeutics to treat cancer, announced that today a poster highlighting positive results in a Phase 2 trial of NOV-002 in combination with neoadjuvant chemotherapy treatment in patients with stage IIB-IIIC HER-2/neu negative invasive breast cancer is being presented by the Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine at the AACR Breast Cancer Symposium in San Antonio, TX.

13 Dec 2010

CTCs in metastatic breast cancer patients linked to cancer recurrence, poor survival rates

Metastatic breast cancer patients who had circulating tumor cells (CTCs) in their blood before or after high-dose chemotherapy (HDCT) followed by autologous stem cell transplantation had poor outcomes, according to researchers from the University of Texas MD Anderson Cancer Center.

13 Dec 2010

Research News and Research

Presence of circulating tumor cells in early-stage breast cancer doubles risk of relapse and death

New groundbreaking research advances understanding of HIV

News outlets examine flooding in Pakistan four months on

Higher co-payments lead to early discontinuation of life-saving therapy for breast cancer

New DNA-based testing technology for tuberculosis treatment

EMEA calls for Europe-wide ban on blood donation from ME/CFS patients

Small amounts of mobility can reduce hospital stay for elderly patients

Lowering legal drinking age would be ineffective in reducing binge drinking in colleges

Xeloda may reduce recurrence of faster growing breast cancers: Study

Study finds Haitian cholera strain resembles one from South Asia, carries mutation that increases severity

New initiative launched to fight cystic fibrosis

Research programs embody the promise of anti-aging medicine.

Combination therapy improves tumor response in HER2-positive breast cancer patients

More sensitive screening tests needed to reduce ovarian cancer deaths

Prostate cancer study identifies 295 genes associated with clinical recurrence following radical prostatectomy

UAB researchers pinpoint protein that causes nephrotic syndrome

Rate of health care-associated infections in developing countries more than double U.S., European rates, study finds

Multi-unit dwellings contribute to children's exposure to tobacco smoke

Novelos NOV-002 demonstrates positive results in Phase 2 neoadjuvant breast cancer trial

CTCs in metastatic breast cancer patients linked to cancer recurrence, poor survival rates

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