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p53 activation offers a novel strategy for cancer therapy

A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.

9 Dec 2010

Exergen's TemporalScanner demonstrates accuracy in temperature assessment for surgical patients

Temperatures taken orally or by temporal artery thermometry "are an accurate means of temperature assessment for adult patients undergoing colorectal or gynecology surgery," according to analysis published by the Journal of PeriAnesthesia Nursing. Accurate temperature readings are necessary to determine when to intervene for patients at all stages of their hospitalizations but especially during and immediately after surgical procedures to avoid post-operative complications.

9 Dec 2010

Texas leaders cut spending for Medicaid, Wyo. begins to set up state exchange

"State leaders, trying to dig out of a hole in the current two-year budget before the next one has to be whacked, ordered agencies Tuesday to further curb spending. Agency chiefs were told in a letter that they must reduce expenditures by 2.5% in the remaining nine months of the fiscal year. Managers of the state Medicaid program immediately announced they would cut another 1% from the fees paid to doctors, dentists and hospitals, along with 2% in payments to nursing homes and home health care providers. The decreases take effect Feb. 1, and they come on top of 1% cuts that kicked in just before Labor Day" (Garrett, 12/8).

9 Dec 2010

New objective criteria for evaluating hemostatic efficacy in treatment of VWD

Octapharma USA researchers presented new stringent, objective criteria used in the evaluation of hemostatic efficacy in the treatment of von Willebrand disease and reported on their application of these criteria in clinical trials during the recently completed National Hemophilia Foundation Annual Meeting.

9 Dec 2010

Annual survey ranks states on health, health care

An annual survey ranks state's overall health and gives snap shots of specific measures including crime, air pollution and smoking rates.

9 Dec 2010

New technique jumpstarts growth of nerve fibers to reverse stroke damage

A new technique that jumpstarts the growth of nerve fibers could reverse much of the damage caused by strokes, researchers report in the Jan. 7, 2011 issue of the journal Stroke.

9 Dec 2010

Senators announce deal to 'fix' Medicare doctor payments - for now

Senate leaders announced a deal late Tuesday to stave off deep cuts to physicians' Medicare payments by repurposing money set aside for the health law, Politico reports. The deal, announced by Senate Majority Leader Harry Reid, D-Nev., and Minority Leader Mitch McConnell, R-Ky., changes ... "how much money consumers would have to repay if they receive too large a subsidy in the health insurance exchanges after 2014.

9 Dec 2010

Home health care technology could help patients improve their health, overall well-being: Study

Home health care technology may provide one important solution to global concerns about how to sustain health care systems threatened by rising costs and manpower shortages, but such a change faces multiple obstacles to adoption, according to a new RAND Corporation study.

9 Dec 2010

Personalized medicine advocates push for better reimbursement system

The U.S. reimbursement for diagnostic tests is outdated and inhibits the development of more personalized tests for patients, according to a report released Tuesday by the Personalized Medicine Coalition.

9 Dec 2010

Anchor Therapeutics announces publication describing pepducin technology as novel approach to target GPCR

Anchor Therapeutics today announced the publication of new research in the Proceedings of the National Academy of Sciences USA. The paper describes the identification and characterization of a pepducin-based allosteric agonist that targets CXCR4, a chemokine G protein-coupled receptor found on hematopoietic stem cells and other bone marrow-derived cells.

9 Dec 2010

Expert panel explores how to engage pediatricians, primary care physicians in preventing childhood obesity

As the prevalence of childhood obesity approaches epidemic levels, physicians on the "front line" need to become more involved in obesity prevention and weight management to reverse this dangerous trend among their young patients. But several obstacles discourage pediatricians and other primary care physicians from taking a more active role in managing childhood obesity.

9 Dec 2010

ADHD, developmental RD have common genetic influences: Study

Attention Deficit Hyperactivity Disorder and developmental reading disability are complex childhood disorders that frequently occur together; if a child is experiencing trouble with reading, symptoms of ADHD are often also present.

9 Dec 2010

NIH to create new translational science center

National Institutes of Health (NIH) Director Francis Collins on Tuesday announced the agency is moving forward on plans to create a new research center focused on translational science, after NIH's advisory board voted to create the new center, Science's "Science Insider" blog reports (Kaiser, 12/7).

9 Dec 2010

Docs distrust hospitals; Americans divided over health law; Children's hospitals lose discounts on orphan drugs

"The successful implementation of the new health care reform law will hinge on physicians and hospitals working out trust issues with one another," according to a new PricewaterhouseCoopers survey. "The reform law requires increased collaboration and information sharing between physicians and hospitals, including through new accountable care organization arrangements, to reduce costs and increase quality."

9 Dec 2010

India, EU trade agreement will not restrict ability for India's pharmaceutical firms to export generic drugs, official says

"India and the European Union (EU) have agreed that the comprehensive bilateral trade agreement being negotiated by the two will not result in an intellectual property regime that restricts the ability of Indian pharmaceutical firms to export generic or off-patent drugs by being far more stringent than the TRIPS [Trade-Related Aspects of International Property Rights] regime of the World Trade Organization," LiveMint.com reports in an article that describes recent debates over the agreement.

9 Dec 2010

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Bionovo, today announced the publication of a study demonstrating that ERb causes cancer cell growth arrest by inactivating critical genes and enzymes responsible for cell growth. These results provide evidence that drugs that stimulate the production of or activate ERb are potential new therapies to prevent breast cancer.

9 Dec 2010

Three drug companies to pay $421 million in fraud settlement

Los Angeles Times: Three pharmaceutical firms — Roxane, Abbott Laboratories and B. Braun Medical — "agreed to pay more than $421 million to settle claims of defrauding Medicare and Medicaid — the latest in a string of large healthcare fraud settlements announced by the Justice Department. The drug companies charged one set of prices to doctors and pharmacies but reported another set of inflated figures that were used as benchmarks by government insurers reimbursing healthcare providers, authorities said" (Zajac, 12/8).

9 Dec 2010

Medulloblastoma subtypes are separate diseases with different origins

International effort led by St. Jude Children's Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancers.

8 Dec 2010

Private insurers, employee wellness programs seek to control costs

Modern Healthcare: "Private insurers may be better at controlling healthcare costs than Medicare, according to a Health Affairs study of two Texas cities. The study is a follow-up to a widely read 2009 New Yorker article by Atul Gawande that showed per-capita Medicare spending in McAllen, Texas, was 86% higher than in El Paso.

8 Dec 2010

WHO endorses rapid TB test

"The World Health Organization endorsed a new, rapid test for tuberculosis Wednesday that cuts the diagnosis time for patients from months to hours," CNN reports (Gray, 12/8).

8 Dec 2010

Research News and Research

p53 activation offers a novel strategy for cancer therapy

Exergen's TemporalScanner demonstrates accuracy in temperature assessment for surgical patients

Texas leaders cut spending for Medicaid, Wyo. begins to set up state exchange

New objective criteria for evaluating hemostatic efficacy in treatment of VWD

Annual survey ranks states on health, health care

New technique jumpstarts growth of nerve fibers to reverse stroke damage

Senators announce deal to 'fix' Medicare doctor payments - for now

Home health care technology could help patients improve their health, overall well-being: Study

Personalized medicine advocates push for better reimbursement system

Anchor Therapeutics announces publication describing pepducin technology as novel approach to target GPCR

Expert panel explores how to engage pediatricians, primary care physicians in preventing childhood obesity

ADHD, developmental RD have common genetic influences: Study

NIH to create new translational science center

Docs distrust hospitals; Americans divided over health law; Children's hospitals lose discounts on orphan drugs

India, EU trade agreement will not restrict ability for India's pharmaceutical firms to export generic drugs, official says

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Three drug companies to pay $421 million in fraud settlement

Medulloblastoma subtypes are separate diseases with different origins

Private insurers, employee wellness programs seek to control costs

WHO endorses rapid TB test

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