Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Drug repositioning strategy identifies potential new treatments for epilepsy

Drug repositioning-- taking known drugs and identifying new applications for them--is an attractive concept for speeding up the process of bringing drugs to human testing for unmet medical needs.

11 Dec 2018

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

Cancer Research UK and AstraZeneca have announced today (Monday) that they are opening a new center in the UK, dedicated to realizing the full potential of functional genomics in the discovery and development of new drugs for patients with cancer.

10 Dec 2018

Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to research published in the December 7, 2018 online issue of Neurology.

10 Dec 2018

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Researchers at the University of Maryland School of Medicine's Maryland Psychiatric Center and Institute for Genome Sciences, along with researchers at the University of Maryland School of Pharmacy, have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia.

5 Dec 2018

Latest advances in AI for aging and longevity research

Insilico Medicine, one of the leaders in artificial intelligence for drug discovery, biomarker development, digital medicine, and aging research announced today the publication of its recent paper titled "Artificial Intelligence for Aging and Longevity Research: Recent Advances and Perspectives" in Ageing Research Reviews, one of the highest-impact journals in the field.

3 Dec 2018

Scientist.com and Allele Biotechnology partner to develop therapeutic nanoantibodies

Scientist.com, the world's leading marketplace for outsourced scientific services, and Allele Biotechnology & Pharmaceuticals Inc., a leading San Diego-based preclinical-stage biopharmaceutical company, have partnered to develop nanoantibodies for therapeutic applications.

3 Dec 2018

Aurora Biomed organizes 2018 Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the "2018 Shunde Biomedical Industry Investment Promotion Conference" which ran in parallel with the Precision Medicine and Ion Channel Retreat was successfully held at the Ramada Plaza Hotel, Shunde, Guang Dong, China.

3 Dec 2018

Insilico Medicine to present work on AI for Drug Discovery at the AI World Conference

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at the AI World Conference in Boston on December 4th.

30 Nov 2018

First-of-its-kind undertaking to study genetic, biological factors that contribute to development of opioid use disorder

The Coriell Institute for Medical Research, Cooper University Health Care and Cooper Medical School of Rowan University (CMSRU) are launching the Camden Opioid Research Initiative (CORI), a first-of-its-kind undertaking to investigate the genetic and biological factors that contribute to the development of opioid use disorder (also referred to as opioid dependence or addiction).

29 Nov 2018

The Native Antigen Company launches ground-breaking Zika virus immunoassays

The Native Antigen Company has launched a series of ground-breaking immunoassays for Zika virus, offering researchers in academia, public health and drug discovery the capability to work with unprecedented levels of specificity and sensitivity.

29 Nov 2018

Insights from the Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the 2018 Shunde Biomedical Industry Investment Promotion Conference was successfully held at the Ramada Plaza Hotel, Shunde, GuangDong, China

From Aurora Biomed Inc. 29 Nov 2018

Researchers create largest publicly available virtual library of macrolide scaffolds

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library - called V1M - contains chemical structures and computed properties for 1 million macrolide scaffolds with potential for use as antibiotics or cancer drugs.

29 Nov 2018

Scientists develop new technique for identifying small molecules

A UCLA-led team of scientists has developed a new technique that will enable researchers to easily and quickly determine the structures of organic molecules using very small samples.

28 Nov 2018

New nanoscale technique developed to get more information from the blood of cancer patients

A technique to get more information from the blood of cancer patients than previously possible has been developed.

28 Nov 2018

CytoReason announces publication of new model for translating data from mouse models to human disease

CytoReason, developer of the world's first machine learning platform for human immune system cell-level simulation, today announces publication of a groundbreaking new model for translating data from mouse models to human disease.

27 Nov 2018

Photographic aging clock uses advances in Artificial Intelligence to predict human age

There are many factors that influence the aging process. Unlocking these factors can lead to valuable insights into what impacts the condition and health of the human body and reveal how to minimize these impacts.

26 Nov 2018

AXT to introduce LUMICKS’ product lines for dynamic single-molecule analysis to Australia

AXT is pleased to announce that they have recently signed a distribution agreement with LUMICKS (Netherlands) that further strengthens their life science product portfolio.

From SPT Labtech 26 Nov 2018

Researchers harness visible light to develop safer building block for drug discovery

When you reach for a bottle of acetaminophen, you may be looking for relief from a headache. But if you take more than what is recommended, the drug can damage your liver.

22 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Cytocybernetics receives NIMH award to move into neuronal drug development

Cytocybernetics, a University at Buffalo spinoff, has received a $250,000 Small Business Innovation Research award from the National Institute of Mental Health (NIMH) to move into a new market: neuronal drug development.

20 Nov 2018

Drug Discovery News and Research

Further Reading

Drug repositioning strategy identifies potential new treatments for epilepsy

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Latest advances in AI for aging and longevity research

Scientist.com and Allele Biotechnology partner to develop therapeutic nanoantibodies

Aurora Biomed organizes 2018 Shunde Biomedical Industry Investment Promotion Conference

Insilico Medicine to present work on AI for Drug Discovery at the AI World Conference

First-of-its-kind undertaking to study genetic, biological factors that contribute to development of opioid use disorder

The Native Antigen Company launches ground-breaking Zika virus immunoassays

Insights from the Shunde Biomedical Industry Investment Promotion Conference

Researchers create largest publicly available virtual library of macrolide scaffolds

Scientists develop new technique for identifying small molecules

New nanoscale technique developed to get more information from the blood of cancer patients

CytoReason announces publication of new model for translating data from mouse models to human disease

Photographic aging clock uses advances in Artificial Intelligence to predict human age

AXT to introduce LUMICKS’ product lines for dynamic single-molecule analysis to Australia

Researchers harness visible light to develop safer building block for drug discovery

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Cytocybernetics receives NIMH award to move into neuronal drug development

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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