Immune System News and Research

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Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Updated booster shots vital for keeping COVID-19 in check

Between natural infection and a global vaccination campaign, most people now have some immunity against the virus that causes COVID-19.

3 Apr 2023

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

Probiotic E. coli secretes proteins of therapeutic value into its surroundings

Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.

31 Mar 2023

Targeting bad bacteria and the immune system in isolation may help fight deadly infections

Twenty to 50 per cent of all critically ill patients contract potentially deadly infections during their stay in the intensive care unit or in hospital after being in the ICU – markedly increasing the risk of death.

31 Mar 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

31 Mar 2023

New model can speed up the evaluation process for drugs used to combat cervical cancer

Researchers at Oregon State University have created a means of speeding up and improving the evaluation process for drugs used to combat cervical cancer.

31 Mar 2023

Music therapy proves effective in treating depression for ADHD in children and adolescents

How music therapy can improve the treatment of depression in children with Attention deficit-hyperactivity disorder (ADHD).

30 Mar 2023

Certain T cells in human blood produce acetylcholine that regulates blood pressure and inflammation

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation.

30 Mar 2023

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

30 Mar 2023

CAR T-cell therapy improves quality of life for patients with blood cancers

Chimeric antigen receptor T-cell (CAR-T) therapy has transformed cancer treatment, yet relatively few studies have investigated the impact of the therapy on longitudinal patient quality of life – an aspect of care that often suffers from receiving traditional intensive cancer medications, such as chemotherapy.

30 Mar 2023

ERC Advanced Grant to support research on the immune system's role in Alzheimer's disease

Alzheimer's disease is traditionally regarded as neurodegenerative disease, an illness that results in progressive neuronal damage due to protein accumulation.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

New research may upend long-held scientific dogma about short telomeres and cancer risk

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

30 Mar 2023

Scientists uncover how some skin cancers resist treatment at the end of life

Scientists have found out how some skin cancers stop responding to treatment at the end of life.

30 Mar 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation -; the transplantation of living cells, tissues and organs from one species to another -; two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

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Immune System News and Research

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Updated booster shots vital for keeping COVID-19 in check

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Probiotic E. coli secretes proteins of therapeutic value into its surroundings

Targeting bad bacteria and the immune system in isolation may help fight deadly infections

Transposable elements in various cancers could be used to harness novel immunotherapies

High consumption of common artificial sweetener lowers activation of T-cells in mice

New model can speed up the evaluation process for drugs used to combat cervical cancer

Music therapy proves effective in treating depression for ADHD in children and adolescents

Certain T cells in human blood produce acetylcholine that regulates blood pressure and inflammation

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

CAR T-cell therapy improves quality of life for patients with blood cancers

ERC Advanced Grant to support research on the immune system's role in Alzheimer's disease

Study shows how neutrophils play a key role in cancer immunotherapy success

New research may upend long-held scientific dogma about short telomeres and cancer risk

Scientists uncover how some skin cancers resist treatment at the end of life

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Drugs to activate STING could help prevent cancer metastasis

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