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Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

Washington State University researchers have determined how a protein that helps cells fight viruses can also cause genetic mutations that lead to cancer.

10 Feb 2016

ESCMID gathers more solid data to better assess Zika virus risks, prepares for possible outbreak in Africa, Europe

Experts at the European Society of Clinical Microbiology and Infectious Diseases – an organization promoting research, risk assessment, knowledge sharing and best practices in the fight against infectious diseases – are developing tools to monitor the spread of the Zika virus and are conducting research to gather more solid data to better assess the risks associated with the infection.

10 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Muscle protein titin plays vital role in Frank-Starling mechanism

Researchers at Illinois Institute of Technology and Loyola University have discovered new clues in the 100-year-old mystery of the Frank-Starling law of the heart: What makes the heart contract more strongly at longer lengths given the same level of calcium activation?

10 Feb 2016

Penn investigators devise new method to map 'transcriptome'

A new way of mapping the "transcriptome" -- the collection of RNA read-outs that are expressed by a cell's active genes -- has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2016

Structural movie reveals step-by-step creation of chemical that plays important role in some cancers

An international team of scientists led by the University of Liverpool has produced a 'structural movie' revealing the step-by-step creation of an important naturally occurring chemical in the body that plays a role in some cancers.

10 Feb 2016

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

Cadavers have long been one of the most important resources for anatomy teaching in medical school. Now, they are also at the forefront of cutting-edge genetics teaching, thanks to innovative thinking by professors at the Lewis Katz School of Medicine at Temple University.

10 Feb 2016

ZAO provides platform for scientists, clinicians to share new research and clinical data on Zika

ZAO provides a platform for scientists and clinicians to publish their findings and source data on Zika and its mosquito vectors within days of submission, so that research, medical and government personnel can keep abreast of the rapidly evolving outbreak.

10 Feb 2016

Yale study examines sex-related social differences in infants at risk for autism

Infant girls at risk for autism pay more attention to social cues in faces than infant boys, according to a Yale School of Medicine study -- the first one known to prospectively examine sex-related social differences in at-risk infants.

10 Feb 2016

Mayo Clinic researchers discover new bacterial species that triggers Lyme disease in people

Mayo Clinic researchers, in collaboration with the Centers for Disease Control and Prevention and health officials from Minnesota, North Dakota and Wisconsin, have discovered a new bacterial species that causes Lyme disease in people. The new species has been provisionally named Borrelia mayonii. Prior to this finding, the only species believed to cause Lyme disease in North America was Borrelia burgdorferi.

9 Feb 2016

$Certain genes could lead to stress fracture injuries$

Certain genes could lead to stress fracture injuries

In a paper published in The Official Journal of the International Purine Club University of Liverpool researchers have successfully identified how certain genes can contribute towards a person's susceptibility to stress fracture injuries. This research provides a platform for further research into providing a personalised health approach to this common sports injury.

9 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

Scientists set to develop new wearable technology to help stroke patients

Scientists at the University of Southampton are to develop and trial a new wearable technology to help people who have had a stroke recover use of their arm and hand.

9 Feb 2016

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts.

9 Feb 2016

Study shows association between traffic-related air pollution and dark spots on the skin

A largescale study that included women from Germany and China has demonstrated a link between levels of traffic-related air pollution and air pollution-associated gases with the formation of dark spots on the skin, known as lentigenes. The most pronounced changes were observed on the cheeks of Asian women over the age of 50.

8 Feb 2016

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels.

8 Feb 2016

University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

The University of Oxford and SomaLogic announced today that they have agreed to undertake a number of collaborative projects that will employ SomaLogic's proprietary SOMAmer reagents and SOMAscan assay technologies to discover and characterize protein biomarkers for a range of clinical diseases and conditions.

8 Feb 2016

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science.

8 Feb 2016

Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

New personalized DNA-based digital assay has potential to dramatically impact CML management

The outcomes of chronic myeloid leukemia (CML) have dramatically improved as the result of tyrosine kinase inhibitor (TKI) treatment. Use of a TKI regimen can lower the blood CML biomarker to levels imperceptible by current detection methods. For patients in "molecular remission," however, uncertainties remain regarding whether they will relapse or if treatment should be discontinued.

8 Feb 2016

Laboratory News and Research

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

ESCMID gathers more solid data to better assess Zika virus risks, prepares for possible outbreak in Africa, Europe

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

Muscle protein titin plays vital role in Frank-Starling mechanism

Penn investigators devise new method to map 'transcriptome'

Structural movie reveals step-by-step creation of chemical that plays important role in some cancers

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

ZAO provides platform for scientists, clinicians to share new research and clinical data on Zika

Yale study examines sex-related social differences in infants at risk for autism

Mayo Clinic researchers discover new bacterial species that triggers Lyme disease in people

Certain genes could lead to stress fracture injuries

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

Scientists set to develop new wearable technology to help stroke patients

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

Study shows association between traffic-related air pollution and dark spots on the skin

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Aggression influences new nerve cell production in the brain

New personalized DNA-based digital assay has potential to dramatically impact CML management

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