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PBS-Bio announces three new contracts to develop cancer therapy

In an industry that faces increasing challenges in delivering new drugs to patients, Predictive Biomarker Sciences (PBS-Bio) today announced three new contracts aimed at bringing new medicines to the marketplace.

20 Oct 2010

More education and attention needed on inflammatory breast cancer

Inflammatory breast cancer (IBC), an aggressive and rare malignancy, is often initially misdiagnosed as an infection or rash. However, getting the correct diagnosis quickly is critical for patients because the disease spreads beyond the breast in a matter of just days or weeks.

20 Oct 2010

$More studies needed on bisphosphonates therapy and fracture risk$

More studies needed on bisphosphonates therapy and fracture risk

On October 13, the Food and Drug Administration published a warning to doctors and patients about an increased risk of thigh fractures with a widely used group of bone-strengthening drugs called bisphosphonates. This warning was much awaited in the light of a report published in the American Journal of Bone and Mineral Research in September titled "Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Report of a Task Force of the American Society for Bone and Mineral Research."

20 Oct 2010

Study finds massive blood transfusion associated with severe complications

A study presented at this year's American Society of Anesthesiologists Annual Meeting indicates that massive blood transfusion is associated with a significant increase in perioperative risk for mortality, cardiopulmonary complications, and wound-related and infectious complications in the long term.

20 Oct 2010

First in vivo screening system for complete human nuclear hormone receptor family

The InDanio screening system can be used, for example, to functionally characterize 'orphan' receptors - those for which their natural ligands or specific function are unknown - and thus qualify them as potential targets for drug discovery. The system can also be used to screen compound libraries in order to identify and refine potential new drugs that target NR proteins.

20 Oct 2010

New sandwich wheat bread is an excellent source of antioxidants

In its continuing commitment as a leader in the bread industry, Texas-based Mrs Baird's becomes the first major baking company in its region to fortify its line of sandwich wheat breads, now providing an excellent source of antioxidant vitamins A and E.

20 Oct 2010

Researchers to develop tailor-made pain management strategies for chronic pain

Research presented at this year's American Society of Anesthesiologists Annual Meeting offers new data in the quest to develop tailor-made pain management strategies based upon a patient's genetic predisposition and other important factors.

20 Oct 2010

Neuralstem updates Phase I human clinical trial of spinal cord stem cells for ALS

Neuralstem, Inc. updated the progress of its ongoing Phase I human clinical trial of the company's spinal cord stem cells in the treatment of ALS (Amyotrophic Lateral Sclerosis, or Lou Gehrig's disease) at Emory University in Atlanta, Georgia.

20 Oct 2010

Microsulis tissue ablation systems presented at London meeting

Dr Peter Clegg, from the University of Bath microwave science team, who invented and developed the Microsulis microwave tissue ablation systems for destroying tumours, presented an overview of the success of this technology at the recent 'Changing Worlds Showcase Impact of University Research' meeting held in London.

20 Oct 2010

Carbon dioxide plays a role in gene regulation: Research

UCD Conway researchers have found that carbon dioxide (CO2) is not only involved in climate change and a waste product of respiration in cells but also plays an active role in regulating the genes involved in inflammation and innate immunity. Their research findings were highlighted recently in the The Journal of Immunology.

20 Oct 2010

Prostate cancer can risk of colon cancer: Study

Men with prostate cancer should be especially diligent about having routine screening colonoscopies, results of a new study by gastroenterologists at the University at Buffalo indicate.

20 Oct 2010

EPO grants new patent to Silence Therapeutics’ RNAi structural modification technology

Silence Therapeutics plc announces that the European Patent Office (EPO) has granted a new patent that provides broad protection on novel aspects of the RNAi structural modification technology known as the Zamore Design Rules.

20 Oct 2010

New approaches to explore causes of autoimmunity and immune deficiency diseases

A newly identified regulatory process affecting the biology of immune system T cells should give scientists new approaches to explore the causes of autoimmunity and immune deficiency diseases.

20 Oct 2010

FDA approves Boehringer Ingelheim's Pradaxa for stroke risk reduction in patients with non-valvular AF

The US Food and Drug Administration (FDA) has approved Pradaxa® (dabigatran etexilate), Boehringer Ingelheim's novel, oral direct thrombin inhibitor for stroke risk reduction in patients with non-valvular atrial fibrillation (AF) marking the first approval of a new oral anticoagulant in the U.S. in more than 50 years.

20 Oct 2010

Study reveals how cells crank up cancer activators

A new technique that searches blood for the tiniest remnants of broken down proteins has revealed new information about how cells crank up cancer activators called proteases. The results improve researchers' understanding of the mechanics of breast cancer and point to where to look for possible indicators of early disease.

20 Oct 2010

Cataract surgery also reduces car crashes

Cataract surgery not only improves vision and quality of life for older people, but is also apparently a way to reduce the number of car crashes. The research will be presented today's at the Scientific Program of the 2010 American Academy of Ophthalmology (AAO) - Middle East-Africa Council of Ophthalmology (MEACO) Joint Meeting.

20 Oct 2010

Aspirin before cardiac surgery reduces postoperative cardiocerebral complications

A study presented at the American Society of Anesthesiologists 2010 Annual Meeting revealed that use of aspirin before cardiac surgery reduced postoperative cardiocerebral complications, including stroke, myocardial ischemia, heart block and cardiac arrest by more than 33 percent when compared to patients who did not use aspirin.

20 Oct 2010

Smokers have more complications and higher death rate after surgery than non-smokers

Results from a clinical study presented at ANESTHESIOLOGY 2010 found that smokers have significantly more complications post-surgery than non-smokers, including a higher death rate.

20 Oct 2010

Study finds ketamine-propofol combination effective for pediatric procedural sedation

Procedural sedation and analgesia is an essential element of care for children requiring painful procedures in the emergency department. The practice of combining ketamine and propofol, two common medications used in emergency departments, has become more popular. However, until recently, it was unclear whether this practice was superior to the use of either agent alone, especially in children.

20 Oct 2010

NIAID announces four new contracts for clinical trials to address problem of antimicrobial resistance

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced four new contracts for large-scale clinical trials that address the problem of antimicrobial resistance.

20 Oct 2010

Research News and Research

PBS-Bio announces three new contracts to develop cancer therapy

More education and attention needed on inflammatory breast cancer

More studies needed on bisphosphonates therapy and fracture risk

Study finds massive blood transfusion associated with severe complications

First in vivo screening system for complete human nuclear hormone receptor family

New sandwich wheat bread is an excellent source of antioxidants

Researchers to develop tailor-made pain management strategies for chronic pain

Neuralstem updates Phase I human clinical trial of spinal cord stem cells for ALS

Microsulis tissue ablation systems presented at London meeting

Carbon dioxide plays a role in gene regulation: Research

Prostate cancer can risk of colon cancer: Study

EPO grants new patent to Silence Therapeutics’ RNAi structural modification technology

New approaches to explore causes of autoimmunity and immune deficiency diseases

FDA approves Boehringer Ingelheim's Pradaxa for stroke risk reduction in patients with non-valvular AF

Study reveals how cells crank up cancer activators

Cataract surgery also reduces car crashes

Aspirin before cardiac surgery reduces postoperative cardiocerebral complications

Smokers have more complications and higher death rate after surgery than non-smokers

Study finds ketamine-propofol combination effective for pediatric procedural sedation

NIAID announces four new contracts for clinical trials to address problem of antimicrobial resistance

A guide to advancing biotherapeutic research eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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