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Researchers find mechanism that alters expression of key genes to make windows of stress-related neuroplasticity

Chronic stress can lead to changes in neural circuitry that leave the brain trapped in states of anxiety and depression. But even under repeated stress, brief opportunities for recovery can open up, according to new research at The Rockefeller University.

23 Dec 2015

Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Researchers from Boston University, the Cleveland Clinic, Banner Alzheimer's Institute and Brigham and Women's Hospital in Boston, have been awarded a $16 million grant from the National Institutes of Health/National Institute of Neurological Disorders and Stroke.

23 Dec 2015

Researchers identify child pedestrian behaviors that promote accidents

"Look both ways before you cross the street" may be sage advice, but it is also apparently necessary for children as old as 13, according to a new study by Ben-Gurion University of the Negev (BGU) researchers, who have pinpointed many of the behaviors that lead to child pedestrians being hit by cars.

23 Dec 2015

Researchers describe epigenetic mechanisms underlying the development of cerebellum

From before birth through childhood, connections form between neurons in the brain, ultimately making us who we are. So far, scientists have gained a relatively good understanding of how neural circuits become established, but they know less about the genetic control at play during this crucial developmental process.

23 Dec 2015

Novel drug shows promise in mouse models of human metastatic breast cancer

A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive to static, and no longer shedding cells that can colonize distant organs of the body. Indeed, most patients with breast and other forms of cancer who succumb to the illness do so because of the cancer's unstoppable spread.

23 Dec 2015

Commonly used diabetes drug may have potential to prevent, treat preeclampsia

An article published today in the American Journal of Obstetrics and Gynecology reports that a commonly-used drug for the treatment of diabetes, metformin, may have the potential to prevent and treat preeclampsia. Metformin has long been used to treat diabetes in both non-pregnant and pregnant patients, and is considered safe during pregnancy.

22 Dec 2015

Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

Forge Therapeutics, Inc., a biotechnology company developing innovative medicines using a breakthrough drug discovery platform targeting metalloproteins, announced today it has obtained an exclusive license from the University of California San Diego to patent rights related to novel metalloprotein inhibitors discovered in the laboratory of Forge Therapeutics scientific co-founder Professor Seth Cohen, Ph.D.

22 Dec 2015

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

After observing that some gastrointestinal disease in premature human and mouse infants progresses only when certain immune system white blood cells go into inflammatory overdrive, Johns Hopkins researchers have found that giving large doses of vitamin A to mice converts those blood cells into inflammation suppressors and reduces the severity of the disease, compared to untreated mice.

22 Dec 2015

Study reveals new genetic factors linked to age-related macular degeneration

An international study of about 43,000 people has significantly expanded the number of genetic factors known to play a role in age-related macular degeneration (AMD), a leading cause of vision loss among people age 50 and older.

22 Dec 2015

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy.

22 Dec 2015

UM student awarded grant for research on human immune system

A hardworking University of Montana undergraduate student will spend the next two and half years studying the hardest-working cell in the human immune system.

22 Dec 2015

Smokers who see graphic warning labels on cigarette packs have more negative feelings about smoking

A new study is the first to provide real-world evidence of the effectiveness of smoking warning labels that include graphic photos of the damage caused by regular tobacco use.

22 Dec 2015

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

Alexza Pharmaceuticals, Inc. today announced interim results of its Phase 2a study of AZ-002 (Staccato alprazolam) in epilepsy patients. AZ-002 produced a dose-related decrease in mean Standardized Photosensivity Range (SPR), the primary endpoint in the study.

21 Dec 2015

IL obtains 510(k) clearance for ACL TOP Family 50 Series Hemostasis Testing Systems

Instrumentation Laboratory today announced the 510(k) clearance of their latest innovation, the ACL TOP Family 50 Series Hemostasis Testing Systems, by the US Food and Drug Administration.

21 Dec 2015

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

A group of Russian scientists, including Dr Elena Kostryukova, the Head of the Laboratory of Postgenomic Research in Biology of the Scientific Research Institute of Physical-Chemical Medicine and a researcher at MIPT (Moscow Institute of Physics and Technology), and Maria Vakhitova, an MIPT postgraduate student, has discovered that the presence of certain bacteria in the gut may be linked to the development of type 2 diabetes.

21 Dec 2015

Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

Luminex Corporation today announced that it has received FDA clearance for its NxTAG Respiratory Pathogen Panel that detects 20 clinically relevant viral and bacterial respiratory pathogens, including the atypical bacteria Chlamydophila pneumoniae and Mycoplasma pneumonia.

20 Dec 2015

New vaccine shows promise against Middle East respiratory syndrome in dromedary camels

An international research project with the involvement of Universitat Autònoma de Barcelona and the Animal Health Research Centre (IRTA-CReSA), has designed a vaccine shown to be effective in protecting dromedaries against the coronavirus (CoV) that causes Middle East respiratory syndrome (MERS).

18 Dec 2015

QMUL-led scientists develop new type of synthetic bone graft

Scientists led by Queen Mary University of London (QMUL) have developed a new type of synthetic bone graft that boosts the body's own ability to regenerate bone tissue and could produce better outcomes for patients.

18 Dec 2015

UCLA study may help resolve a neurological mystery

UCLA researchers have found that space-mapping neurons - the GPS system in the brain - have a strong dependence on what is being looked at when triangulating location, a finding that resolves a neurological mystery that has vexed scientists for more than four decades.

18 Dec 2015

Synthetic biomaterial aids in regeneration of skin cells to improve wound healing

Some skin wounds, such as diabetic ulcers, are chronic and may never heal; others, such as burn wounds, are often large and difficult to treat, resulting in pain, infection and scarring. Researchers at the University of California, Los Angeles, funded by the National Institutes of Health, have developed a synthetic biomaterial that fills wounds and aids in regeneration of skin cells, which ultimately improves wound healing.

18 Dec 2015

Laboratory News and Research

Researchers find mechanism that alters expression of key genes to make windows of stress-related neuroplasticity

Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Researchers identify child pedestrian behaviors that promote accidents

Researchers describe epigenetic mechanisms underlying the development of cerebellum

Novel drug shows promise in mouse models of human metastatic breast cancer

Commonly used diabetes drug may have potential to prevent, treat preeclampsia

Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

Study reveals new genetic factors linked to age-related macular degeneration

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

UM student awarded grant for research on human immune system

Smokers who see graphic warning labels on cigarette packs have more negative feelings about smoking

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

IL obtains 510(k) clearance for ACL TOP Family 50 Series Hemostasis Testing Systems

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

New vaccine shows promise against Middle East respiratory syndrome in dromedary camels

QMUL-led scientists develop new type of synthetic bone graft

UCLA study may help resolve a neurological mystery

Synthetic biomaterial aids in regeneration of skin cells to improve wound healing

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