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Roche files direct de novo application to FDA for Anti-Mullerian assay

Roche announced today that it has filed a direct de novo application to the U.S. Food and Drug Administration for a fully automated Anti-Mullerian (AMH) assay for use on Roche's full portfolio of laboratory analyzers. The determination of AMH is useful for the assessment of ovarian reserve in women presenting to infertility clinics for evaluation in conjunction with other clinical and laboratory findings.

17 Dec 2015

Wearable exoskeletons: what interactions are possible? An interview with Dr Juan C. Moreno

Wearable exoskeletons are coming to stay. Technological advancements in embedded computation and wearable mechatronics are enabling the production of new wearable exoskeletons that were not feasible a decade ago

17 Dec 2015

RBHS Chancellor leads study to eliminate chronic viral hepatitis

Chronic viral hepatitis has a reputation for being a silent killer. The infection often goes undetected until the symptoms of advanced liver cancer appear. By that point, a patient has a five-year survival rate, according to the American Cancer Society.

17 Dec 2015

New study suggests that musclin may promote muscle health

A new study in mice shows that exercise causes muscle to release a peptide that builds the muscle's capacity for energy production and increases physical endurance, allowing for longer and more intense exercise.

17 Dec 2015

Understanding how thought arises from brain structure

Using 20 years of functional magnetic resonance imaging (fMRI) data from tens of thousands of brain imaging experiments, computational neuroscientists Hava Siegelmann and a postdoctoral colleague at the University of Massachusetts have created a geometry-based method for massive data analysis to reach a new understanding of how thought arises from brain structure.

17 Dec 2015

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery.

17 Dec 2015

Slow eating keeps childhood obesity at bay, study finds

Waiting 30 seconds in between bites of food allows children to realize they're no longer hungry before they overeat--preventing excessive weight gain. That's the conclusion of a study published in the Dec. 15 issue of the journal Pediatric Obesity by an international team of researchers, including bioengineers at the University of California, San Diego.

17 Dec 2015

Berkeley Lab researchers develop new mouse model for most common form of breast cancer

The first clinically-relevant mouse model of human breast cancer to successfully express functional estrogen receptor positive (ER+) adenocarcinomas has been developed by researchers at Lawrence Berkeley National Laboratory.

17 Dec 2015

Diamonds may hold key to the future for NMR and MRI technologies

Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California Berkeley have demonstrated that diamonds may hold the key to the future for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) technologies.

17 Dec 2015

Standing up or walking for just five minutes could help prevent Type 2 diabetes

Women who have an inactive daily routine and are at high risk of Type 2 diabetes can help prevent the condition by regularly standing up or walking for five minutes at a time, a new study has found.

17 Dec 2015

Researchers find new way to prevent or reduce pathologies caused by malformed proteins

Improperly formed proteins can cause a host of serious illnesses, from muscular dystrophy to cystic fibrosis. A question of enormous import in research, beyond the challenge of determining how malformed proteins contribute to specific disease processes, is figuring out ways to prevent or reduce the pathologies they cause.

16 Dec 2015

Study offers new view of how cancer cells transform normal cells through 'metastatic hijacking'

Metastasis - or the spread of cancer from one part of the body to other parts - accounts for more than 90 percent of cancer-related deaths. Although the cells that seed metastasis and the sites that they tend to travel to have been increasingly studied over the years, little has been known about how cancer migrates from a primary site, such as breast tissue, to a secondary site, such as the brain or bone marrow.

16 Dec 2015

Study paves way for development of novel cancer therapeutics

A team of scientists, comprising researchers from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, and the VIB Laboratory of Molecular Cancer Biology, has revealed the mechanism by which tumor cells elevate levels of MDM4, a protein that is highly expressed in cancer cells but not in normal adult tissues.

16 Dec 2015

Human-gut-on-a-chip model offers hope for patients suffering from IBD

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications.

16 Dec 2015

Bile acid may help treat fatty liver disease and obesity

A bile acid that can turn off a receptor in the gut has prevented and reversed fatty liver disease in mice, according to an international team of researchers. The compound may help treat certain metabolic disorders, such as Type 2 diabetes and obesity, as well.

16 Dec 2015

TSRI scientists track how HIV-fighting antibodies develop over time

In a new study, a team led by scientists at The Scripps Research Institute tracked how a family of these HIV-fighting antibodies develops over time. The research shows how a future vaccine might trigger the immune system to produce these antibodies more effectively.

16 Dec 2015

Heloise Anne Pereira named 2016 National Academy of Inventors Fellow

University of Oklahoma Health Sciences Center Professor Heloise Anne Pereira has been named a 2016 National Academy of Inventors Fellow, a high professional distinction awarded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society.

16 Dec 2015

Molecular signatures can predict flu vaccine responses in young and old

What factors inhibit strong responses to seasonal flu vaccines in the elderly? Why do anti-flu antibodies last longer after vaccination in some people? Answers are emerging from an Emory University-based systems biology analysis of blood samples from more than 400 volunteers who received seasonal flu vaccines. Bali Pulendran, PhD, led a team of researchers who tracked patterns of gene expression, known as molecular signatures, of strong immune responses in volunteers' blood across five consecutive seasons from 2007 to 2011.

16 Dec 2015

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015

Four UC Santa Barbara engineers named 2015 NAI fellows

Four UC Santa Barbara engineers have been elected to the National Academy of Inventors for 2015. Recognized for their "highly prolific spirit of invention," professors John Bowers, Craig Hawker, Umesh Mishra and Galen Stucky are among the newest fellows elected by the organization.

16 Dec 2015