Adolescents News and Research

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New drug regimen is safe and effective in children with cystic fibrosis

An international, open-label Phase 3 study, co-led by Susanna McColley, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, found that a regimen of three drugs (elexacaftor/tezacaftor/ivacaftor) that targets the genetic cause of cystic fibrosis was safe and effective in 6-11-year-olds with at least one copy of F508del mutation in the CFTR gene, which is estimated to represent almost 90 percent of the cystic fibrosis population in the United States.

19 Mar 2021

UNH study: More than 50% of at-risk children are not receiving behavioral health services

Researchers at the University of New Hampshire have found that more than 50% of children in high-risk populations in the United States are not receiving behavioral health services that could improve their developmental outcomes when it comes to mental and physical health problems.

18 Mar 2021

Adverse childhood experiences predict greater performance-enhancing substance use in young adults

A new study published in the journal Substance Use and Misuse has found that adverse childhood experiences, such as physical and sexual abuse and neglect, predict greater performance-enhancing substance use in young adults.

17 Mar 2021

A complete genetic and clinical analysis of individuals with SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

17 Mar 2021

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

The COVID-19 pandemic has claimed over 2.67 million lives in less than a year and a half. However, it is uncommon in children, with less than 2% of the cases being in individuals below the age of 19. Most of these are of mild severity, with the clinical features of severe COVID-19 being rare in this age group.

17 Mar 2021

COVID-19 is more difficult to diagnose in children and adolescents, finds study

The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread to over 192 countries and territories, causing an enormous loss of lives and economic devastation.

17 Mar 2021

New report calls for comprehensive smoke-free policies

A new WHO report, Tobacco Control To Improve Child Health And Development, calls for raising awareness among practitioners and policymakers about the importance of strong tobacco control measures for protecting the health and development of children, including banning tobacco advertising, implementing 100% smoke-free environments and raising taxes on tobacco.

16 Mar 2021

Executive control differences in autism may be the result of a unique approach

A new study by UC Davis MIND Institute researchers suggests that executive control differences in autism spectrum disorder (ASD) may be the result of a unique approach, rather than an impairment.

13 Mar 2021

Exposure to COVID-19 can cause rare but life-threatening pediatric condition

Exposure to SARS-Co-V2, the virus that causes COVID-19, can put otherwise healthy children and adolescents at risk for Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but possibly life-threatening pediatric condition that can cause severe inflammation in organs like the heart, brain, lungs, kidneys and gastrointestinal system.

12 Mar 2021

Study reveals how lung alveolus forms at cellular level

Researchers from Children's Hospital of Philadelphia have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air.

11 Mar 2021

Study recommends prevention programs to address suicidal behaviors among ethnic minority adolescents

Associations between strong predictors of suicidal behaviors over the life course, such as adverse childhood events (ACEs), remain understudied among youth of color. Although not previously considered high risk, suicide attempts among Black youth increased 73% between 1991 and 2017.

11 Mar 2021

Inter-arm blood pressure differences in children could lead to wrong diagnosis

Blood pressure measurements in children and adolescents should be taken from both arms after new research showed substantial differences could be seen depending on which arm was used.

10 Mar 2021

RNA editing events influence gene expression and phenotypic manifestation

Combining computational mining of big data with experimental testing in the lab, researchers at Children's Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.

10 Mar 2021

Study finds reduction in pediatric emergency visits, hospitalizations during the pandemic

Amid the COVID-19 pandemic, children's hospitals across the United States have seen signification reductions in the number of children being treated for common pediatric illnesses like asthma and pneumonia, according to a new multicenter study led by Monroe Carell Jr. Children's Hospital at Vanderbilt.

9 Mar 2021

Study examines effects of problematic internet use on older adolescents

Most teenagers don't remember life before the internet. They have grown up in a connected world, and being online has become one of their main sources of learning, entertaining and socializing.

9 Mar 2021

Computerized, remote training program alleviates negative emotions in preadolescents

Anxiety levels in the United States are rising sharply and have especially intensified in younger populations.

9 Mar 2021

Researchers measure self-paced physical and cognitive activity to manage concussion

Concussion, a form of traumatic brain injury, is a common injury among children and teens. Concussions can have adverse effects on physical, cognitive, emotional and sleep health.

9 Mar 2021

Outdoor activities help improve mental health and well-being of teenagers during the pandemic

A study from North Carolina State University found outdoor play and nature-based activities helped buffer some of the negative mental health impacts of the COVID-19 pandemic for adolescents.

8 Mar 2021

Study identifies worrying trends between teenage screen use and lower physical activity

Two thirds of children use more than one screen at the same time after school, in the evenings and at weekends as part of increasingly sedentary lifestyles, according to new research at the University of Leicester.

5 Mar 2021

Experimental safety switch reduces severity of CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

4 Mar 2021

Adolescents News and Research

New drug regimen is safe and effective in children with cystic fibrosis

UNH study: More than 50% of at-risk children are not receiving behavioral health services

Adverse childhood experiences predict greater performance-enhancing substance use in young adults

A complete genetic and clinical analysis of individuals with SCN2A-related disorders

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

COVID-19 is more difficult to diagnose in children and adolescents, finds study

New report calls for comprehensive smoke-free policies

Executive control differences in autism may be the result of a unique approach

Exposure to COVID-19 can cause rare but life-threatening pediatric condition

Study reveals how lung alveolus forms at cellular level

Study recommends prevention programs to address suicidal behaviors among ethnic minority adolescents

Inter-arm blood pressure differences in children could lead to wrong diagnosis

RNA editing events influence gene expression and phenotypic manifestation

Study finds reduction in pediatric emergency visits, hospitalizations during the pandemic

Study examines effects of problematic internet use on older adolescents

Computerized, remote training program alleviates negative emotions in preadolescents

Researchers measure self-paced physical and cognitive activity to manage concussion

Outdoor activities help improve mental health and well-being of teenagers during the pandemic

Study identifies worrying trends between teenage screen use and lower physical activity

Experimental safety switch reduces severity of CAR-T immunotherapy-related side effects

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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