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New molecular pathway identified for early onset coronary artery disease

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s – with normal cholesterol levels and no other risk factors -; to develop coronary artery disease has been identified, according to researchers with UTHealth Houston.

7 Jul 2023

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

In a new study, National Institutes of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to a weaker and less diverse antibody response to viral infections.

7 Jul 2023

‘It was a bloodbath’: Rare dialysis complication can kill, and more could be done to stop it

Nieltje Gedney was half-asleep in her West Virginia home, watching murder mysteries over the hum of a bedside hemodialysis machine, when she felt something warm and wet in her armpit.

7 Jul 2023

Patient aggression causes lasting harm to medical receptionists

University of Queensland research has found verbal and physical abuse of medical receptionists by patients is rife, and causing lasting harm.

6 Jul 2023

Multiple discoveries open new paths for early prediction of Parkinson's disease trajectories

Hand tremors and slowed movements are two of the most widely recognized hallmarks of Parkinson's disease, and for many sufferers the first indication that something is amiss.

6 Jul 2023

Study provides insights into the molecular mechanism of Batten disease

Neuronal Ceroid Lipofuscinosis are a group of devastating neurodegenerative lysosomal storage disorders that begin in childhood. Mutations in CLN3 gene lead to a NCL called Batten disease, characterized by the progressive loss of vision, movement, and cognition.

6 Jul 2023

Does a healthy diet protect against dementia and slow the pace of biological aging?

Study tested whether healthy diets slowed biological aging and, thus, dementia.

6 Jul 2023

Medicaid expansion under the ACA linked to increased palliative care use

More people with advanced cancers in the United States received critical palliative care services, according to new findings by researchers at the American Cancer Society (ACS).

5 Jul 2023

TBI-associated depression may be a distinct disorder

A new study led by Shan Siddiqi, MD, from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

5 Jul 2023

Reproductive impact of changes in the vaginal microbiome of obese women

Study explores the impact of obesity on vaginal microbiota and reproduction.

5 Jul 2023

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

Researchers present the mechanisms by which SARS-CoV-2 could infect the brain and affect memory.

5 Jul 2023

Black individuals who experience racial discrimination more likely to crave alcohol

Alcohol craving is associated with relapse following alcohol use disorder (AUD) treatment. A new study is the first to examine how distinct experiences of interpersonal racial discrimination contribute to elevated alcohol craving.

4 Jul 2023

Climate change's impact on health and healthcare in Northern NSW: Urgent action needed

A systematic review published in the International Journal of Environmental Research and Public Health describes the impact of climate change on health and health services in Northern New South Wales, Australia. This region is considered a “hotspot” for floods and bushfires in Australia.

4 Jul 2023

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

Research explores the potential benefits of herbs and spices in rheumatic diseases, highlighting their bioactive compounds and medicinal properties. It provides an updated review of their mechanisms of action and summarizes human studies in Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia.

4 Jul 2023

Growth factor study reveals potential breakthrough in obesity management

Study discusses the effects of a growth factor that showed promising results in mice in an obesity trial.

4 Jul 2023

Was there a change in the incidence of diabetes in children and adolescents after the onset of the COVID-19 pandemic?

Study compares the incidence rates of pediatric T1D and 2D during and before SARS-CoV-2.

4 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

SIRT1: Unlocking the secrets to better vascular health through resveratrol and energy restriction

Research investigates the effects of SIRT1 activation through resveratrol supplementation and energy restriction on vascular function in adults. The study reveals that both interventions increase circulating SIRT1, reduce sympathetic activity, and have positive impacts on vascular reactivity, indicating potential benefits for vascular health.

3 Jul 2023

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Regular physical exercise, such as resistance training, can prevent Alzheimer's disease, or at least delay the appearance of symptoms, and serves as a simple and affordable therapy for Alzheimer's patients.

3 Jul 2023

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Stress News and Research

New molecular pathway identified for early onset coronary artery disease

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

‘It was a bloodbath’: Rare dialysis complication can kill, and more could be done to stop it

Patient aggression causes lasting harm to medical receptionists

Multiple discoveries open new paths for early prediction of Parkinson's disease trajectories

Study provides insights into the molecular mechanism of Batten disease

Does a healthy diet protect against dementia and slow the pace of biological aging?

Medicaid expansion under the ACA linked to increased palliative care use

TBI-associated depression may be a distinct disorder

Reproductive impact of changes in the vaginal microbiome of obese women

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

Black individuals who experience racial discrimination more likely to crave alcohol

Climate change's impact on health and healthcare in Northern NSW: Urgent action needed

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

Growth factor study reveals potential breakthrough in obesity management

Was there a change in the incidence of diabetes in children and adolescents after the onset of the COVID-19 pandemic?

Smoking and HPV found to increase risk of head and neck cancer

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

SIRT1: Unlocking the secrets to better vascular health through resveratrol and energy restriction

Resistance training could be a simple and affordable therapy for Alzheimer's patients

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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