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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled -; a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Researchers develop new approach for studying HBV in the lab

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded effective therapeutics.

13 Apr 2023

New AI tool accurately predicts aggressiveness of colorectal cancer

A new artificial intelligence model designed by researchers at Harvard Medical School and National Cheng Kung University in Taiwan could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer, the second deadliest cancer worldwide.

13 Apr 2023

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

13 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Researchers use a quick, portable process to produce promising virus-fighting protein

A multidisciplinary research team has produced a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak.

12 Apr 2023

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Researchers examine antibiotic resistance genes and their mobility in Bifidobacteriales and Lactobacillales species.

11 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Henry Ford Health research teams are launching a series of clinical studies in partnership with Illumina Inc., a global leader in DNA sequencing and array-based technologies, to assess the impact of comprehensive genomic testing in various disease areas.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

Researchers reviewed the latest studies on nutritional exposures during prenatal and early childhood stages.

11 Apr 2023

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Researchers examine the effects of electronic cigarette (e-cigarette) vapor on gut microbiome, body weight, and systemic inflammation levels.

11 Apr 2023

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.

10 Apr 2023

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DNA News and Research

Further Reading

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Researchers develop new approach for studying HBV in the lab

New AI tool accurately predicts aggressiveness of colorectal cancer

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

Changes to tumor DNA can help predict cancer's next move

Research reveals molecular features of rare mtDNA mutations

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Researchers discover important drug target for preventing blood cancer

Researchers use a quick, portable process to produce promising virus-fighting protein

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Cornell receives $9.5 million NIH grant for chronic fatigue research

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Study expands the knowledge about gut viral diversity in healthy infants

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Immunotherapy response in patients with advanced melanoma depends on prior treatments

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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