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Blocking release of VEGFs may inhibit tumor growth

Researchers at the University of Helsinki, Finland, and the Paul Scherrer Institute (PSI) in Villigen, Switzerland, have determined the crystal structure of the ligand binding domain of a vascular endothelial growth factor (VEGF) receptor in complex with one of its ligands (VEGF-C).

19 Jan 2010

Calsed earns proprietary clinical gold standard status from Decision Resources

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Celgene/Nippon Kayaku's Calsed earns Decision Resources' proprietary clinical gold standard status in 2013 for the treatment of extensive-disease small-cell lung cancer, following its approval for the indication in 2012.

19 Jan 2010

New study indicates appendicitis may be caused by viral infection

The researchers evaluated data over a 36-year period from the National Hospital Discharge Survey and concluded in a paper appearing in the January issue of Archives of Surgery that appendicitis may be caused by undetermined viral infection or infections, said Dr. Edward Livingston, chief of GI/endocrine surgery at UT Southwestern and senior author of the report.

19 Jan 2010

Preventing two oestrogen influencing receptors from 'conversing' may prevent breast cancer

CANCER RESEARCH UK scientists have shown for the first time how preventing two receptors - 'cell antennae' - communicating with each other can influence the activity of oestrogen, the hormone that fuels the progression of breast cancer in many women. The research is published in Genes and Development.

19 Jan 2010

Unique partnership leverages funds and technology to track and improve breast screening program

The Canadian Breast Cancer Foundation - Atlantic announced today a first-of-its-kind partnership between the breast screening programs of Nova Scotia and Newfoundland and Labrador that yield benefits that could extend to the rest of Canada and beyond.

19 Jan 2010

Foresters renews commitment as the international underwriter of Children’s Miracle Network’s Radiothon program

Foresters™, a life insurance provider that champions the well-being of families, has renewed its commitment as the international underwriter of Children’s Miracle Network’s Radiothon program. Foresters support of Children’s Miracle Network, a children’s charity that raises funds for more than 170 children’s hospitals, spans 20 years and three countries - the US, Canada and the UK.

19 Jan 2010

Study of link between vitamin D deficiency and hypertension uses SunTech Medical’s Oscar 2 ABPM

A study led by Dr. William White and Dr. Pooja Luthra at the University of Connecticut Health Center is using the Oscar 2™, 24 hour ambulatory blood pressure monitor (ABPM) to investigate a possible link between vitamin D deficiency and hypertension.

19 Jan 2010

New findings support the development of vaccine against malaria

Walter and Eliza Hall Institute researchers have uncovered a group of proteins that could form the basis of an effective vaccine against malaria.

19 Jan 2010

Sodium oxybate to garner over 15% of the fibromyalgia drug market despite safety concerns

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, despite potential safety concerns, Jazz Pharmaceuticals/UCB's sodium oxybate (JZP-6) will account for more than 15 percent of the fibromyalgia drug market in 2018 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan. Sodium oxybate has demonstrated robust efficacy in Phase III clinical trials for fibromyalgia and interviewed thought leaders are impressed with its effect on several key symptom domains of fibromyalgia, which include pain, sleep and fatigue.

18 Jan 2010

Boehringer Ingelheim, Priaxon announce collaboration in development of mdm2/p53 inhibitors for cancer

Boehringer Ingelheim and Priaxon entered into a worldwide collaboration to research and develop mdm2/p53 inhibitors for the treatment of cancer. Priaxon is providing its innovative and proprietary small molecule drug discovery expertise which is particularly suited to investigate inhibition of protein-protein interactions. p53 is a human tumor suppressor protein.

18 Jan 2010

US hospital emergency departments treat an average 31,500 table saw-related injuries per year

Woodworking is a popular hobby, with table saws being owned and used by an estimated 6 million to 10 million people in the United States. Although table saws are associated with more injuries than any other woodworking tool, there have been no previously published national studies of table saw-related injuries.

18 Jan 2010

Organization of the brain's dictionary

Two hundred years ago, archaeologists used the Rosetta Stone to understand the ancient Egyptian hieroglyphs. Now, a team of Carnegie Mellon University scientists has discovered the beginnings of a neural Rosetta Stone. By combining brain imaging and machine learning techniques, neuroscientists Marcel Just and Vladimir Cherkassky and computer scientists Tom Mitchell and Sandesh Aryal determined how the brain arranges noun representations. Understanding how the brain codes nouns is important for treating psychiatric and neurological illnesses.

18 Jan 2010

Sunlight and vitamin D deficiency linked to 17 varieties of cancer

For humans, sunlight and vitamin D is critically important for the development, growth, and maintenance of a healthy body, from birth until death. "Humans make thousands of units of vitamin D within minutes of whole body exposure to sunlight. From what we know of nature, it is unlikely such a system evolved by chance," states Dr. John Cannell, Executive Director, Vitamin D Council.

18 Jan 2010

Babraham Institute research may lead to new means of making purified T cells

Research from the Babraham Institute, reported today in the Journal of Experimental Medicine, provides new insights into how our immune system produces T cells, a type of white blood cell that is an essential part of the body's immune surveillance system for fighting infection. The findings pave the way for a new means of making purified T cells, which gets over one of many hurdles faced in the use of T cells in regenerative medicine and transplantations, and in addition will open up new avenues of research and applications in drug and toxicity testing in industry.

18 Jan 2010

Neurosurgical journals influence neurosurgeons and their patients

A compendium of articles in the Journal of Neurosurgery (JNS) provides evidence that specialty medical journals are not only an invaluable resource to physicians and researchers, but to the media and public. Clinical and basic science papers do not have to be published in large, high-impact publications to garner attention, and in fact when it comes to specialized areas of medicine such as neurosurgery, publications devoted to the subspecialty produce many citation classics. "Citation classic" is a term given to articles that have been cited more than 400 times.

18 Jan 2010

Research analyses underfunding in state retiree benefits

Research shows that, nationally, states are facing more than $550 billion in unfunded liabilities associated with health care and other non-pension benefits for retired state employees, a situation many states are now struggling to fix. New research from North Carolina State University has identified a number of trends that are consistent among those states with the biggest funding problems - information that may help states find a solution to the funding shortfall.

18 Jan 2010

NIDA researchers receive prestigious PECASE awards

Two researchers from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, have been awarded the White House Office of National Science and Technology Council's Presidential Award for Early Career Scientists and Engineers (PECASE). NIDA grantees Dr. Bruce J. Hinds, III and Dr. Gonzalo E. Torres will receive their awards today during a ceremony at the Commerce Building in Washington, DC.

18 Jan 2010

Leslie Phillips asks Facebook users to vote for NAA in the Chase Community Giving challenge

Texas mom Leslie Phillips joins parents, grandparents, and caregivers around the country in asking Facebook users to vote for the National Autism Association (NAA) in the Chase Community Giving challenge.

18 Jan 2010

Repeal of Texas helmet law results in increased motorcycle fatalities

In Texas, the repeal of a motorcycle helmet law has been followed by a sharp increase in fatal motorcycle crashes, according to a study in the January Southern Medical Journal, official journal of the Southern Medical Association.

18 Jan 2010

Medical innovation needed despite current economic problems, says Eli Lilly CEO

In the keynote address at a Town Hall Los Angeles luncheon event today, John C. Lechleiter, Ph.D., chairman and CEO of Eli Lilly and Company, said that in the current challenging economic times, sustaining our nation's edge in innovation and improving our focus on medical innovation's richest resource – people – is imperative to achieving prosperity and health in the coming decade. His speech focused on bioscience innovation, a sector in which Los Angeles boasts one of the largest concentrations of jobs in the country.

18 Jan 2010

Research News and Research

Blocking release of VEGFs may inhibit tumor growth

Calsed earns proprietary clinical gold standard status from Decision Resources

New study indicates appendicitis may be caused by viral infection

Preventing two oestrogen influencing receptors from 'conversing' may prevent breast cancer

Unique partnership leverages funds and technology to track and improve breast screening program

Foresters renews commitment as the international underwriter of Children’s Miracle Network’s Radiothon program

Study of link between vitamin D deficiency and hypertension uses SunTech Medical’s Oscar 2 ABPM

New findings support the development of vaccine against malaria

Sodium oxybate to garner over 15% of the fibromyalgia drug market despite safety concerns

Boehringer Ingelheim, Priaxon announce collaboration in development of mdm2/p53 inhibitors for cancer

US hospital emergency departments treat an average 31,500 table saw-related injuries per year

Organization of the brain's dictionary

Sunlight and vitamin D deficiency linked to 17 varieties of cancer

Babraham Institute research may lead to new means of making purified T cells

Neurosurgical journals influence neurosurgeons and their patients

Research analyses underfunding in state retiree benefits

NIDA researchers receive prestigious PECASE awards

Leslie Phillips asks Facebook users to vote for NAA in the Chase Community Giving challenge

Repeal of Texas helmet law results in increased motorcycle fatalities

Medical innovation needed despite current economic problems, says Eli Lilly CEO

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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