Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

Fujitsu announces development of molecular simulation technology for drug discovery

Fujitsu Laboratories Ltd. and Fujitsu Limited today announced the development of molecular simulation technology for drug discovery that can accurately estimate binding affinity, which represents the degree to which proteins that can cause diseases (target proteins) bind to chemical substances that could become candidate drugs.

7 May 2018

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials.

4 May 2018

Charles River Laboratories Expands Services for Early Discovery Screening

Charles River Laboratories International, Inc. recently announced the expansion of its service capabilities in early discovery screening.

4 May 2018

Researchers characterize new protein that plays key role in genetic stability of cells

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterized a new protein that is important to the genetic stability of our cells.

3 May 2018

Sylentis presents clinical study results of new treatment for dry eye syndrome

Sylentis, Pharmaceutical Company belonging to the PharmaMar Group, has presented results from the clinical studies carried out with tivanisiran for the treatment of dry eye syndrome and that has enabled the start-up of the Phase III "Helix" clinical trial.

3 May 2018

Moving beyond traditional 'magic bullet' approach for discovering new drugs

It's time to move beyond the traditional 'magic bullet' approach for discovering new drugs and start leveraging the full complexity of Mother Nature, say Vanderbilt Professor of Chemistry Brian Bachmann and Assistant Professor of Cell and Developmental Biology Jonathan Irish.

3 May 2018

UCLA researchers report promising drug strategy to block tau transmission

Alzheimer's disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau.

3 May 2018

Following five lifestyle behaviors could prolong life expectancy for men and women

Maintaining a healthy lifestyle, including eating a healthy diet, regular exercise and not smoking, could prolong life expectancy at age 50 by 14 years for women and just over 12 years for men, according to new research in the American Heart Association's journal Circulation.

30 Apr 2018

Novel cell-based screening array reduces time and cost of drug discovery

Porvair Sciences has collaborated with Persomics Inc. to develop and supply ANSI/SLAS format Arrays as an OEM product for their ImagineArray™ platform.

From Porvair Sciences Limited 28 Apr 2018

Insilico’s CEO to deliver presentation on “Artificial Intelligence for Aging Research”

Insilico Medicine, a Baltimore-based company specializing in the application of next-generation artificial intelligence for drug discovery, biomarker development and aging research, announces the presentation of its CEO, Alex Zhavoronkov, at the Pioneers 18 Conference, May 25, 2018, Vienna, Austria.

28 Apr 2018

Researchers discover significant distortions in leading genetics study method

Many conclusions drawn from a common approach to the study of human genetics could be distorted because of a previously overlooked phenomenon, according to researchers at the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai and collaborators from Massachusetts General Hospital and the Broad Institute.

25 Apr 2018

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression.

19 Apr 2018

Finding the 'keyhole' to beat obesity at the cellular level

An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.

19 Apr 2018

Bio-Techne expands automation capabilities of popular RNAscope ISH technology

Bio-Techne has expanded the automation capabilities of its popular Advanced Cell Diagnostics -branded RNAscope in situ hybridization technology with the launch of several new and updated assays.

From Bio-Techne 18 Apr 2018

New black Porvair Krystal UV Quartz microplates for Circular Dichroism measurements

Porvair Sciences introduces new black Krystal UV Quartz bottomed microplates that offer excellent optical transmission in the wavelength range 185 nm to 1100 nm making them ideal for labs looking to make Circular Dichroism (CD) measurements.

From Porvair Sciences Limited 17 Apr 2018

SYGNIS AG extends manufacturing capability for Lightning-Link technology

SYGNIS AG, the Group which includes Expedeon Holdings, Expedeon, and C.B.S. Scientific Company, today announced it has extended the manufacturing capability for its Lightning-Link technology, currently marketed under the Expedeon brand, to support scalability and bulk production of antibodies.

16 Apr 2018

Tradeshow Talks with POREX

News Medical talk to POREX to find out why they are exhibiting at analytica 2018.

From Porex Corporation 11 Apr 2018

UT Southwestern's Dr. Nijhawan selected for ASCI's 2018 Seldin-Smith Award

UT Southwestern's Dr. Deepak Nijhawan became a co-recipient of the 2018 Donald Seldin-Holly Smith Award for Pioneering Research. The award recognizes Dr. Nijhawan's work identifying targets for cancer treatment.

10 Apr 2018

Drug Discovery News and Research

Further Reading

New model based on combination of GANs with reinforcement learning for drug discovery

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

Fujitsu announces development of molecular simulation technology for drug discovery

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Charles River Laboratories Expands Services for Early Discovery Screening

Researchers characterize new protein that plays key role in genetic stability of cells

Sylentis presents clinical study results of new treatment for dry eye syndrome

Moving beyond traditional 'magic bullet' approach for discovering new drugs

UCLA researchers report promising drug strategy to block tau transmission

Following five lifestyle behaviors could prolong life expectancy for men and women

Novel cell-based screening array reduces time and cost of drug discovery

Insilico’s CEO to deliver presentation on “Artificial Intelligence for Aging Research”

Researchers discover significant distortions in leading genetics study method

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

Finding the 'keyhole' to beat obesity at the cellular level

Bio-Techne expands automation capabilities of popular RNAscope ISH technology

New black Porvair Krystal UV Quartz microplates for Circular Dichroism measurements

SYGNIS AG extends manufacturing capability for Lightning-Link technology

Tradeshow Talks with POREX

UT Southwestern's Dr. Nijhawan selected for ASCI's 2018 Seldin-Smith Award

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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